Preparation of TiO2-enriched CaCu3Mn0.1Ti3.9O12 ceramics and their dielectric properties

TiO₂-enriched CaCu₃(Mn_0.1Ti_3.9)O₁₂ (CCMTO) ceramics have been prepared by a two-step method. X-ray diffraction (XRD) and TEM results indicate that TiO₂ particles were partially coated on the surface of CCMTO powders. The dielectric spectra of TiO₂-enriched CCMTO samples showed that the dielectric constant was almost independent of the measured frequency and the dielectric loss was markedly suppressed by increasing the addition of TiO₂. The grain activation energy was calculated and an increase in energy was observed with the addition of TiO₂. This transformation gave influence to grain charge mobility and resulted in transformed dielectric behaviors.     

Chemical Modification of Phage-Displayed Helix-Loop-Helix Peptides to Construct Kinase-Focused Libraries

Conformationally constrained peptides hold promise as molecular tools in chemical biology and as a new modality in drug discovery. The construction and screening of a target-focused library could be a promising approach for the generation of de novo ligands or inhibitors against target proteins. Here, we have prepared a protein kinase-focused library by chemically modifying helix-loop-helix (HLH) peptides displayed on phage and subsequently tethered to adenosine. The library was screened against aurora kinase A (AurA). The selected HLH peptide Bip - 3 retained the α-helical structure and bound to AurA with a K_D value of 13.7 μM. Bip - 3 and the adenosine-tethered peptide Bip - 3 - Adc provided IC₅₀ values of 103 μM and 7.7 μM, respectively, suggesting that Bip - 3 - Adc bivalently inhibited AurA. In addition, the selectivity of Bip - 3 - Adc to several protein kinases was tested, and was highest against AurA. These results demonstrate that chemical modification can enable the construction of a kinase-focused library of phage-displayed HLH peptides.     

Genetic variation of Listeria monocytogenes isolates from domestic and imported foods in Japan

Phylogenetic analyses were carried out on a total of 118 Listeria monocytogenes isolates from foods or food processing environments, and 7 isolates from listeriosis patients in Japan to evaluate the genetic variation in the pathogen in this country. Isolates of serotypes 1/2a, 1/2b and 4b were mainly examined to assess the risk of exposure of humans to L. monocytogenes from foods in Japan. The nucleotide sequences of the part of the iap gene that contains the region encoding the threonine-asparagine repeat units were determined in order to construct phylogenetic trees of the isolates investigated. A phylogram showed high genetic diversity among lineage 2 isolates, while the lineage 1 isolates showed clonal characteristics. The results of the genetic analyses suggested the presence of rare putative lineage 3 isolates and epidemic clone I (ECI) isolates in foods in Japan. The results showed that ECI was also isolated from listeriosis patients. The genetic variation in L. monocytogenes in Japan reported here suggests the necessity of monitoring the pathogen in foods and environments in addition to surveillance of listeriosis patients.     

A pilot survey of 39 Victorian WWTP effluents using a high speed luminescent umu test in conjunction with a novel GC-MS-database technique for automatic identification of micropollutants

In 2007, samples of treated effluent were collected at point of discharge to the environment from 39 wastewater treatment plants (WWTPs) located across Victoria, Australia grouped by treatment type. Sample genotoxicity was assessed with a high-throughput luminescent umu test method using Salmonella typhimurium TL210 strain, with and without addition of a commercially available metabolic activation system. Samples were also screened using a gas chromatographic-mass spectrometric mass-structure database recognition method. A genotoxic response was observed in half of the samples tested without metabolic activation system (相似文献   

Gas absorption into “string-of-beads” liquid flow with chemical reaction: application to carbon dioxide separation

This study examines the performance of “string-of-beads” liquid flow on vertical wires as a novel gas-liquid contact device for gas absorption using a chemically reacting liquid absorbent. The string-of-beads flow is a distinct on-wire liquid-flow pattern consisting of annular thin liquid films sheathing a wire and teardrop-shaped liquid beads alternately aligned on the wire at regular intervals. We have performed experiments of CO₂ absorption by an aqueous monoethanolamine solution in string-of-beads flow on a single wire and have developed an analytic gas-absorption model relevant to the experiments. The model well simulates the CO₂-absorption characteristics observed in the experiments, thereby suggesting the utility of the model in predicting the chemical gas-absorption performance of multiple-wire gas-liquid contactors.     

FIR system identification based on a nonparametric Bayesian model using the Indian buffet process

In this paper, we propose a nonparametric Bayesian model combined with the Indian buffet process (IBP) for a finite impulse response (FIR) system. We develop an FIR system identification method that can simultaneously estimate the number of FIR taps and coefficients. In the proposed model, each FIR tap consists of a coefficient and a gain, and the gain is a binary value. An infinite-dimensional binary vector is composed of binary values, and we assume that this binary vector is generated by the IBP. To identify the FIR system, we specify the likelihood function and prior distributions of the parameters and derive their posterior distributions. We can simultaneously estimate the number of FIR taps and coefficients by sampling from posterior distributions using the Gibbs sampler. Our simulations demonstrate that although the number of FIR taps is unknown, the identification performance of the proposed method in a high signal-to-noise ratio environment is similar to or better than that of the conventional least square solution.     

Study on high performance evaporator with micro‐grooves (Measurement of capillary force in a single groove and modeling of heat and mass transfer)

A micro‐grooved evaporator is composed of µm‐wide grooves on a heat transfer plate in which the inter‐line regions at the liquid–vapor meniscus of coolant become identifiable. The high‐heat performance of the evaporator is realized by this inter‐line region (ILR) where the liquid thin film reduces the thermal resistance on the heat transfer surface. In this report, we propose a numerical simulation model of heat and mass transfer in a single groove to predict its capillary force and heat flux. The capillary force performance (capillary‐rise length in a groove) of a single groove was measured for samples of varying width, superheat, and inclination. The performance was found to be a maximum at a specific groove width of 200–400 µm, which is in good agreement with the predicted results calculated by the proposed model. For a better prediction of capillary‐rise length, the effective capillary force and the effective flow resistance were considered. © 2009 Wiley Periodicals, Inc. Heat Trans Asian Res; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/htj.20257     

Mesophase structure discovered through in-situ X-ray measurement in drawing process of poly(ethylene 2,6-naphthalene dicarboxylate) fiber

The structure development in the continuous laser-heated drawing process of poly(ethylene 2,6-naphthalene dicarboxylate) (PEN) fiber was analyzed by in-situ X-ray diffraction measurement. Because of the rapid and uniform laser heating, and the resultant steady-state nature of the necking-drawing, the structure development after the on-set of necking could be measured in the time resolution of several hundred microseconds. We found for the first time the temporal appearance of meridional (001′) diffraction at several milliseconds after the on-set of necking indicating that the mesophase structure similar to the one reported for poly(ethylene terephthalate) was also formed in the initial stage of fiber structure development of PEN. The d-spacing of the (001′) diffraction 1.230 ± 0.003 nm was shorter than the c-axis lengths of both α and β crystals.