全文获取类型
收费全文 | 2205篇 |
免费 | 7篇 |
专业分类
化学工业 | 17篇 |
建筑科学 | 2篇 |
能源动力 | 1篇 |
轻工业 | 14篇 |
石油天然气 | 2篇 |
无线电 | 1篇 |
冶金工业 | 2173篇 |
自动化技术 | 2篇 |
出版年
2019年 | 1篇 |
2016年 | 1篇 |
2015年 | 2篇 |
2012年 | 1篇 |
2011年 | 2篇 |
2010年 | 3篇 |
2005年 | 1篇 |
2004年 | 2篇 |
2003年 | 7篇 |
2001年 | 1篇 |
2000年 | 1篇 |
1999年 | 68篇 |
1998年 | 739篇 |
1997年 | 427篇 |
1996年 | 266篇 |
1995年 | 153篇 |
1994年 | 112篇 |
1993年 | 116篇 |
1992年 | 13篇 |
1991年 | 20篇 |
1990年 | 15篇 |
1989年 | 28篇 |
1988年 | 16篇 |
1987年 | 19篇 |
1986年 | 21篇 |
1985年 | 22篇 |
1983年 | 1篇 |
1982年 | 8篇 |
1981年 | 13篇 |
1980年 | 11篇 |
1979年 | 2篇 |
1978年 | 3篇 |
1977年 | 33篇 |
1976年 | 66篇 |
1975年 | 4篇 |
1971年 | 1篇 |
1965年 | 1篇 |
1959年 | 3篇 |
1958年 | 1篇 |
1955年 | 1篇 |
1954年 | 1篇 |
1948年 | 2篇 |
1909年 | 1篇 |
1890年 | 3篇 |
排序方式: 共有2212条查询结果,搜索用时 15 毫秒
71.
David A. Conner Ph.D. P.E. Gary J. Grimes Ph.D. Jay Goldman D.SC. P.E. 《Journal of Systems Integration》2000,10(1):81-94
For telemedicine to reach its potential in the Internet2 environment,significant progress must be made in a number of areas. The emergingtelecommunications will include the Internet2 between medicalinstitutions and emerging broadband loop and wireless technologiesfor interconnections to homes. Within the technical environment,problems that must be addressed include the development of robotic-controlled,remote-monitoring devices unique to the various medical specialties;the encoding, transmission, and decoding of raw data specificto the specialized needs of various medical application areas;and the reduction of data for storage and retrieval in patientrecords. Institutionally, human factor and information accessissues with respect to physicians, patients, and non-physicianhealthcare providers must be addressed; healthcare insuranceprovider policies, government regulation, and state licensinglaws must be adapted for a new paradigm of healthcare delivery;and the philosophy of capital investment for the delivery ofhealthcare must be revised.Many current practiceswill be supplanted by home healthcare alternatives, the use ofpatient-initiated preventive healthcare initiatives, and remote-clinicactivity. These applications will result in central record archivingsystems; the need for encryption schemes, virus protection, andvandalism protection; extensive, additional connectivity betweenhealthcare providers and professionals; and new commercial playersin the healthcare arena.The hot applicationareas will include women's health, children's health, healthcarefor senior citizens, home healthcare, well-patient monitoring,and early-detection of medical problems. 相似文献
72.
DK Jones D Lythgoe MA Horsfield A Simmons SC Williams HS Markus 《Canadian Metallurgical Quarterly》1999,30(2):393-397
BACKGROUND AND PURPOSE: Information on the neuropathological changes underlying ischemic leukoaraiosis is only available postmortem, and there are limited data on histological appearances early in the disease. Diffusion tensor imaging allows determination of the directionality of diffusion, which is greater in the direction of white matter bundles. Therefore, the technique might be expected to show loss of anisotropy (directional diffusion) in leukoaraiosis. METHODS: Nine patients with ischemic leukoaraiosis (radiological leukoaraiosis and clinical lacunar stroke) and 10 age-matched controls were studied. Diffusion tensor imaging was performed, and maps of diffusion trace and fractional anisotropy were constructed. Mean values of trace and fractional anisotropy were determined in standard regions of the anterior and posterior white matter in both hemispheres. RESULTS: In all patients with ischemic leukoaraiosis, a characteristic abnormal pattern was found, with loss of anisotropy and increased trace in the white matter. For example, in the right anterior white matter mean (SD) trace/3 was 1.12 (0.33) x10(-3) mm2 s-1 in patients and 0.75 (0.11) in controls (P=0.001). In the same region, fractional anisotropy was 0.53 (0.11) in patients and 0.78 (0.09) in controls (P<0.001). Within the white matter regions, there was a strong negative correlation between mean diffusivity and anisotropy (r=-0.92, P<0.0001). CONCLUSIONS: The characteristic pattern found on diffusion tensor imaging in this patient group is consistent with axonal loss and gliosis leading to impairment to and loss of directional diffusion. The "in vivo histological" information obtained may be useful in monitoring disease progression and in investigating the pathogenesis of the cognitive impairment that may be present. 相似文献
73.
The Sixth International Congress on Schizophrenia Research (ICOSR) took place in Colorado Springs, Colorado, April 12-16, 1997, where over 1,000 scientists presented and listened to the latest developments in the search for the cause and treatment of schizophrenia. The ICOSR is sponsored by Maryland Psychiatric Research Center, Case Western Reserve University, and the William K. Warren Foundation. The National Institute of Mental Health and several pharmaceutical companies contributed generously to the meeting. The ICOSR is co-organized by Dr. Carol A. Tamminga, Maryland Psychiatric Research Center, University of Maryland at Baltimore, and Dr. S. Charles Schulz, Case Western Reserve University, Cleveland, Ohio. The William K. Warren Research Award is given to a senior investigator, who has made outstanding contributions to our understanding of schizophrenia. The fifth William K. Warren Research Award was presented to Dr. Philip S. Holzman in recognition of his contributions to the identification of eye-tracking abnormalities as a potential phenotypic marker of the illness and also in recognition of his work as a lifelong mentor for schizophrenia researchers. The ICOSR Young Investigator Awards are presented to junior investigators who have demonstrated the potential to make significant contributions to research on schizophrenia. These awards promote scientific development by enabling these young researchers to attend the meeting. There were 30 Young Investigator Award winners. The ICOSR meeting is organized into four sessions: (1) a morning plenary session; (2) a plenary lecture; (3) a poster session; and (4) concurrent afternoon oral sessions. The morning plenary sessions are comprised of a set of 30-minute lectures, which provide an overview of a particular topic area relevant to schizophrenia research. The plenary lecture is an invited lecture on a basic topic related to current research efforts in schizophrenia. The poster sessions provide a forum for the presentation of prepublication reports of basic and clinical science projects. The afternoon sessions are a collection of approximately 10 focused presentations on current research projects related to a specific topic area. The purpose of this report is to provide an account of the proceedings from the plenary and afternoon oral sessions. 相似文献
74.
DJ Marcellin-Little A Ferretti SC Roe DJ DeYoung 《Canadian Metallurgical Quarterly》1998,27(3):231-245
OBJECTIVE: To evaluate hinged circular external fixation for correction of antebrachial deformities in dogs. STUDY DESIGN: Uncontrolled clinical trial. ANIMAL POPULATION: Seven client-owned dogs. METHODS: Six dogs had one radius corrected and one dog had both radii corrected. Preoperative planning included measurement of the craniocaudal and mediolateral angular deformities, rotational deformity, length deficit, origin of deformity, graphical or mathematical determination of the amplitude and direction of the actual limb deformity, and frame assembly. RESULTS: Preoperatively, function and cosmesis were assessed to be fair to poor in all dogs. Deformity correction started 48 to 60 hours postoperatively and ranged from 0.46 mm to 1.36 mm twice daily. Hospitalization time ranged from 4 to 6 days. Corrections were mostly made by the owners, at home. Lengthening and angular correction ranged from 3 to 38 mm and 18 degrees to 48 degrees. Mean residual deformities were 2.7% of radial length and 2.7 degrees. The time duration with the circular external fixators in place ranged from 29 to 71 days. Two additional surgeries were necessary in one dog because of wire breakage. Mean follow-up was 40 months. Long-term function and cosmesis were good to excellent in all dogs. CONCLUSION: Although complications were present in six of seven dogs, the outcome of hinged Ilizarov external fixation was successful in all dogs treated for deformities of the antebrachium. CLINICAL RELEVANCE: Despite complex preoperative planning, the placement of hinged circular external fixators is straightforward, and allows precise correction of complex antebrachial deformities with minimal tissue trauma. 相似文献
75.
76.
C Liu AB Bahnson JT Dunigan SC Watkins JA Barranger 《Canadian Metallurgical Quarterly》1998,76(11):773-781
The majority of studies dealing with DNA analyses are made on fixed cells. In this context, the efficiency as fixatives of ethanol, methanol, acetone, Carnoy, Boehm-Sprenger and aldehydes was determined using two different DNA fluorescent probes, Hoechst 33342 and propidium iodide. The purpose of our study was to find the fixative that would provide the best results with respect to the following parameters: aggregates, cell size and granularity, and DNA staining analysis. Using murine fibroblasts, we found that 68% ethanol, 85% methanol and aldehydes did not increase aggregate formation, whereas Carnoy, acetone or Boehm-Sprenger fixatives did. The results show that aldehydes seem to alter cell size least. All fixatives induce an increase in cell granularity, which is very pronounced with alcohols, but aldehydes alter morphology less than alcohols. We observed that the fixatives giving the best resolution with Hoechst 33342 staining lead to a lower measurement variability than with propidium iodide staining. This study leads us to conclude that 68% ethanol and 85% methanol can be considered as appropriate fixatives for flow cytometry studies of DNA content. 相似文献
77.
R Ben Abraham A Blumenfeld M Stein SC Shapira G Paret A Rivkind J Shemer 《Canadian Metallurgical Quarterly》1998,163(11):747-749
Post-thyroidectomy I-131 whole-body scintigraphy is an important aspect in the management of patients with thyroid cancer. The scan is used to detect residual thyroid tissue and distant functioning metastases. Extrathyroid I-131 accumulation does not always denote metastatic disease, and several potential sources of false-positive I-131 scans have been identified. This report presents four cases of benign oral disease as a cause of false-positive I-131 uptake. Benign oral disease has not been documented previously as an important source of false-positive I-131 whole-body scans. 相似文献
78.
Post-traumatic pyogenic liver abscess is a rare disease. We present the case of a 38-year-old man with multilocular liver abscess and pleural empyema following blunt abdominal trauma. The patient had a prodrome lasting 3 months before presenting in our department. The therapy included partial hepatectomy and pleural drainage. Clinical signs, diagnosis and possible therapy are discussed in this case report. 相似文献
79.
FS vom Saal PS Cooke DL Buchanan P Palanza KA Thayer SC Nagel S Parmigiani WV Welshons 《Canadian Metallurgical Quarterly》1998,14(1-2):239-260
Two chemicals previously shown to have estrogenic activity, bisphenol A and octylphenol, were examined for their effects on accessory reproductive organs and daily sperm production in male offspring of mice fed these chemicals during pregnancy. These chemicals are used in the manufacture of plastics and other products, and have been detected in food and water consumed by animals and people. From gestation day 11-17 female mice were fed an average concentration (dissolved in oil) of bisphenol A or octylphenol of 2 ng/g body weight (2 ppb) and 20 ng/g (20 ppb). The 2 ppb dose of bisphenol A is lower than the amount reported to be swallowed during the first hour after application of a plastic dental sealant (up to 931 micrograms; 13.3 ppb in a 70 kg adult). We found that the 2 ng/g dose of bisphenol A permanently increased the size of the preputial glands, but reduced the size of the epididymides; these organs develop from different embryonic tissues. At 20 ng/g, bisphenol A significantly decreased efficiency of sperm production (daily sperm production per g testis) by 20% relative to control males. The only significant effect of octylphenol was a reduction in daily sperm production and efficiency of sperm production at the 2 ng/g dose. A new approach to studying physiologically relevant doses of environmental endocrine disruptors is discussed, particularly with regard to the development of the reproductive organs, the brain, and behavior. 相似文献
80.
SC Guru PK Goldsmith AL Burns SJ Marx AM Spiegel FS Collins SC Chandrasekharappa 《Canadian Metallurgical Quarterly》1998,95(4):1630-1634
The MEN1 gene, mutations in which are responsible for multiple endocrine neoplasia type 1 (MEN1), encodes a 610-amino acid protein, denoted menin. The amino acid sequence of this putative tumor suppressor offers no clue to the function or subcellular location of the protein. We report herein, based on immunofluorescence, Western blotting of subcellular fractions, and epitope tagging with enhanced green fluorescent protein, that menin is located primarily in the nucleus. Enhanced green fluorescent protein-tagged menin deletion constructs identify at least two independent nuclear localization signals (NLS), both located in the C-terminal fourth of the protein. Among the 68 known independent disease-associated mutations, none of the 22 missense and 3 in-frame deletions affect either of the putative NLS sequences. However, if expressed, none of the truncated menin proteins resulting from the 43 known frameshift/nonsense mutations would retain both the NLSs. The precise role(s) of menin in the nucleus remain to be understood. 相似文献