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51.
Shahzad Akbar Muhammad Sharif Muhammad Usman Akram Tanzila Saba Toqeer Mahmood Mahyar Kolivand 《Microscopy research and technique》2019,82(2):153-170
Retina is the interior part of human's eye, has a vital role in vision. The digital image captured by fundus camera is very useful to analyze the abnormalities in retina especially in retinal blood vessels. To get information of blood vessels through fundus retinal image, a precise and accurate vessels segmentation image is required. This segmented blood vessel image is most beneficial to detect retinal diseases. Many automated techniques are widely used for retinal vessels segmentation which is a primary element of computerized diagnostic systems for retinal diseases. The automatic vessels segmentation may lead to more challenging task in the presence of lesions and abnormalities. This paper briefly describes the various publicly available retinal image databases and various machine learning techniques. State of the art exhibited that researchers have proposed several vessel segmentation methods based on supervised and supervised techniques and evaluated their results mostly on publicly datasets such as digital retinal images for vessel extraction and structured analysis of the retina. A comprehensive review of existing supervised and unsupervised vessel segmentation techniques or algorithms is presented which describes the philosophy of each algorithm. This review will be useful for readers in their future research. 相似文献
52.
Syed N. Shah Mushtaq Ahmad Muhammad Zafar Fazal Ullah Wajid Zaman Khafsa Malik Neelam Rashid Saba Gul 《Microscopy research and technique》2019,82(8):1326-1333
Spore morphology of Thelypteridaceae species growing in Malakand Division, Northern Pakistan, was studied using both light microscopy and scanning electron microscopy. The taxa are Christella dentata and Glaphyropteridopsis erubescens in the subfamily Thelypteridoideae, and Phegopteris connectilis, Pseudophegopteris pyrrhorhachis, and Pseudophegopteris levingei in the subfamily Phegopteridoideae. The studied species exhibit differences in spore size, exospore thickness, color, and ornamentation. Spores of the studied species are monolete and medium‐sized, and shape is ellipsoidal in both polar and equatorial views. The average measurement of the polar diameter ranges from 27 μm to 31 μm, whereas in the equatorial direction it varied from 20 μm to 40 μm. The exospore thickness ranges from 1.2 μm to 2.4 μm. Reticulate, laevigate with microgranules, cristate, and coarsely echinate surface ornamentation are observed among the species. Multivariate analysis including unweighted pair group method with arithmetic mean and principal component analysis was used for the grouping and discrimination of species and genera. 相似文献
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Ali Farman Ali Zulfiqar Li Bing-Zhao Qamar Sadia Nazeer Amna Riaz Saba Khan Muhammad Asif Fayyaz Rabia Nawaz Abbasi Javeria 《Water Resources Management》2022,36(9):2989-3005
Water Resources Management - Drought is recurrently occurring in many parts of the globe. In contrast to other natural hazards, drought has complex climatic characteristics. Several environmental... 相似文献
56.
Francesco Traccis Valeria Serra Claudia Sagheddu Mauro Congiu Pierluigi Saba Gabriele Giua Paola Devoto Roberto Frau Joseph Francois Cheer Miriam Melis 《International journal of molecular sciences》2021,22(4)
Cannabis use among pregnant women is increasing worldwide along with permissive sociocultural attitudes toward it. Prenatal cannabis exposure (PCE), however, is associated with adverse outcome among offspring, ranging from reduced birth weight to child psychopathology. We have previously shown that male rat offspring prenatally exposed to Δ9-tetrahydrocannabinol (THC), a rat model of PCE, exhibit extensive molecular, cellular, and synaptic changes in dopamine neurons of the ventral tegmental area (VTA), resulting in a susceptible mesolimbic dopamine system associated with a psychotic-like endophenotype. This phenotype only reveals itself upon a single exposure to THC in males but not females. Here, we characterized the impact of PCE on female behaviors and mesolimbic dopamine system function by combining in vivo single-unit extracellular recordings in anesthetized animals and ex vivo patch clamp recordings, along with neurochemical and behavioral analyses. We find that PCE female offspring do not show any spontaneous or THC-induced behavioral disease-relevant phenotypes. The THC-induced increase in dopamine levels in nucleus accumbens was reduced in PCE female offspring, even when VTA dopamine activity in vivo and ex vivo did not differ compared to control. These findings indicate that PCE impacts mesolimbic dopamine function and its related behavioral domains in a sex-dependent manner and warrant further investigations to decipher the mechanisms determining this sex-related protective effect from intrauterine THC exposure. 相似文献
57.
Mass spectrometry in the diagnosis of thyroid disease and in the study of thyroid hormone metabolism
Marco Borsò Patrizia Agretti Riccardo Zucchi Alessandro Saba 《Mass spectrometry reviews》2022,41(3):443-468
The importance of thyroid hormones in the regulation of development, growth, and energy metabolism is well known. Over the last decades, mass spectrometry has been extensively used to investigate thyroid hormone metabolism and to discover and characterize new molecules involved in thyroid hormones production, such as thyrotropin-releasing hormone. In the earlier period, the quantification methods, usually based on gas chromatography–mass spectrometry, were complicated and time consuming. They were mainly focused on basic research, and were not suitable for clinical diagnostics on a routine basis. The development of the modern mass spectrometers, mainly coupled to liquid chromatography, enabled simpler sample preparation procedures, and the accurate quantification of thyroid hormones, of their precursors, and of their metabolites in biological fluids, tissues, and cells became feasible. Nowadays, molecules of physiological and pathological interest can be assayed also for diagnostic purposes on a routine basis, and mass spectrometry is slowly entering the clinical laboratory. This review takes stock of the advancements in the field of thyroid metabolism that were carried out with mass spectrometry, with special focus on the use of this technique for the quantification of molecules involved in thyroid diseases. 相似文献
58.
This article investigates the nano-milling of multi-grooves on single crystalline copper. To explore the material removal mechanisms, molecular dynamics (MD) simulations were carried on both sequential and simultaneous nano-milling processes. It was found that to obtain quality grooves; a simultaneous multi-grooving requires a larger wall thickness between two adjacent grooves. Under sequential nano-millings or a simultaneous nano-milling with same rotational direction of the tools, the minimum wall thickness can be identified by residual stress distribution analysis. Under a simultaneous nano-milling with opposite rotational direction of the tools, this requirement of minimum wall thickness is better identified by strain rate distribution analysis. Overall, the simultaneous nano-milling with opposite rotational direction of the tools gives the best groove quality. A detailed machinability analysis showed that the groove quality by nano-milling can be improved by increasing the depth of cut and wall thickness between two adjacent grooves. 相似文献
59.
Hosain Darvishi Nasser Behroozi-Khazaei Mahmoud Koushesh Saba Zakaria Alimohammadi Himan Nourbakhsh 《International Journal of Food Science & Technology》2021,56(9):4789-4798
The antioxidant, phenol, ascorbic acid, electrode corrosion and engineering factors of concentration process of kiwifruit juice by ohmic heating-vacuum conditions (OHVC) were evaluated and compared with ohmic heating under atmospheric conditions (OHAC). Results showed that the total phenol content was decreased with an increasing voltage gradient for both heating modes. The OHVC can better save the antioxidant capacity and ascorbic acid of concentrated samples than the OHAC. The processing time of OHVC was significantly higher than the OHAC at the same voltage gradient (P < 0.05). The electrode corrosion rate at the vacuum mode was 7- to 40-fold higher than the atmospheric mode. The energy efficiency at OHAC was lower than the OHVC. The energy consumption was found in the range of 3.37 to 3.75 MJ kg−1 water for OHAC and 4.08 to 11.09 MJ kg−1 water for OHVC. The electrical conductivity under the vacuum mode was lower than the atmospheric mode. 相似文献
60.
Minimizing transmission delays in vehicular ad hoc networks by optimized placement of road-side unit
Wireless Networks - In a vehicular ad hoc network (VANET), a road side unit (RSU) is a network traffic transmitter statically placed along the route to facilitate communication between vehicles and... 相似文献