A review on current trends in potential use of metal-organic framework for hydrogen storage

Hydrogen can be a promising clean energy carrier for the replenishment of non-renewable fossil fuels. The set back of hydrogen as an alternative fuel is due to its difficulties in feasible storage and safety concerns. Current hydrogen adsorption technologies, such as cryo-compressed and liquefied storage, are costly for practical applications. Metal-organic frameworks (MOFs) are crystalline materials that have structural versatility, high porosity and surface area, which can adsorb hydrogen efficiently. Hydrogen is adsorbed by physisorption on the MOFs through weak van der Waals force of attraction which can be easily desorbed by applying suitable heat or pressure. The strategies to improve the MOFs surface area, hydrogen uptake capacities and parameters affecting them are studied. Hydrogen spill over mechanism is found to provide high-density storage when compared to other mechanisms. MOFs can be used as proton exchange membranes to convert the stored hydrogen into electricity and can be used as electrodes for the fuel cells. In this review, we addressed the key strategies that could improve hydrogen storage properties for utilizing hydrogen as fuel and opportunities for further growth to meet energy demands.     

Composite polymeric microsponge-based long-acting gel formulation for topical delivery of mupirocin

Topical delivery of medicaments in a controlled manner is still a promising area of research. Drug-containing dammar gum-ethyl cellulose composite microsponge loaded gel formulation (D-MSPG) was developed for controlled topical delivery of mupirocin. The drug-loaded microsponges (D-MSPs) were formulated by the quasi-emulsion solvent diffusion method and were evaluated for morphology, particle size distribution, entrapment efficiency, thermal properties, and crystallinity. The optimized D-MSPs (entrapment efficiency 91.5 ± 4.0% and particle size of 55.15 ± 2.9 μm) were dispersed in carbopol 934 gel (D-MSPG). The final product was characterized for pH, viscosity, texture, spreadability, consistency, syneresis, in vitro drug release, and ex vivo skin penetration study. A comparative study with marketed formulation was performed. For optimized gel formulation (G4), drug content was 104.19 ± 1.68%, and drug release was 84.19% after 24 h. The pH of the optimized gel was observed to be 6.05 ± 0.04. Viscosity of the optimized gel formulation was found to be 1212.15 ± 434.85 mPa-s at 50 s⁻¹. The steady-state flux (J) in ex vivo skin permeation was observed to be 53.96 μg cm⁻² h⁻¹ and the permeability coefficient was 2.69 cm/h for the optimized gel formulation. According to the findings, the D-MSPG-based formulation strategy can act well to prolong the topical delivery of mupirocin or similar drug molecules.     

Placement and routing in 3D integrated circuits

Three-dimension technologies offer great promise in providing improvements in the overall circuit performance. Physical design plays a major role in the ability to exploit the flexibilities offered in the third dimension, and this article gives an overview of placement and routing methods for FPGA- and ASIC-style designs. We describe CAD techniques for placement and routing in 3D ICs, developed under our 3D analysis and design optimization framework. These approaches address a dichotomy of design styles, both FPGA and ASIC. The factors that are important in each style are different, so that a one-size-fits-all approach is impractical, and therefore, we present separate approaches for 3D physical design for each of these technologies. Hence, our FPGA placement method uses a two-step optimization process that minimizes inter-tier vias first, followed by further optimization within and across tiers. In contrast, the ASIC flow uses cost function weighting to discourage, but not minimize, inter-tier crossings.     

Molecular beacon sequence analysis for detecting drug resistance in Mycobacterium tuberculosis

Strictureplasty for treatment of symptomatic intestinal strictures secondary to Crohn's disease is being performed with increasing frequency. To determine the overall clinical results after strictureplasty for Crohn's disease, all patients undergoing this procedure were prospectively studied. Between 6/1/89 and 2/1/97, 57 Crohn's disease patients underwent 60 operations utilizing strictureplasties. A total of 109 strictureplasties were performed (90 Heineke-Mikulicz, 6 Finney, and 13 side-to-side isoperistaltic). The 30-day perioperative morbidity was 12%, with complications being less common for patients undergoing elective versus unscheduled operations (p < 0.002). Recurrence of Crohn's disease requiring operation was seen in seven patients after a mean follow-up of 38 months. The estimated cumulative recurrence rate after 2 years was 15 +/- 6% (+/- standard error) and 22 +/- 10% at 5 years. A recurrence developed at the site of the previous strictureplasty in only five cases. Strictureplasty is a safe, effective means of providing long-term surgical palliation to selected patients with Crohn's disease. Perioperative complication rates are comparable to those seen with standard surgical treatment, and recurrences are not excessive.     

A 90-nm logic technology featuring strained-silicon

A leading-edge 90-nm technology with 1.2-nm physical gate oxide, 45-nm gate length, strained silicon, NiSi, seven layers of Cu interconnects, and low-/spl kappa/ CDO for high-performance dense logic is presented. Strained silicon is used to increase saturated n-type and p-type metal-oxide-semiconductor field-effect transistors (MOSFETs) drive currents by 10% and 25%, respectively. Using selective epitaxial Si/sub 1-x/Ge/sub x/ in the source and drain regions, longitudinal uniaxial compressive stress is introduced into the p-type MOSEFT to increase hole mobility by >50%. A tensile silicon nitride-capping layer is used to introduce tensile strain into the n-type MOSFET and enhance electron mobility by 20%. Unlike all past strained-Si work, the hole mobility enhancement in this paper is present at large vertical electric fields in nanoscale transistors making this strain technique useful for advanced logic technologies. Furthermore, using piezoresistance coefficients it is shown that significantly less strain (/spl sim/5 /spl times/) is needed for a given PMOS mobility enhancement when applied via longitudinal uniaxial compression versus in-plane biaxial tension using the conventional Si/sub 1-x/Ge/sub x/ substrate approach.     

Effect of water of crystallization on synthesis of nanocrystalline ceria by non-hydrolytic method

Nanocrystalline ceria has been synthesized by a non-hydrolytic method using organic solvent and precipitant. The effect of the source compound on final nanocrystalline powder was investigated. The cerium nitrate hexahydrate subjected to different vacuum/thermal treatments to get cerium source compound having different extent of water of crystallization. The nanoceria, synthesized from these compounds was characterized by TGA-MS, XRD, HR-TEM and AFM.     

Effects of enzymes in diets with varying energy levels on growth and egg production performance of Japanese quail

The present study was conducted to evaluate the effect of feed‐grade enzyme supplementation in diets with varying levels of energy on the performance of growing and laying Japanese quails. Day‐old Japanese quails, 504 in number, were subjected to six dietary treatments with six replicates at each treatment. Each replicate had 14 chicks. The dietary treatments consisted of three energy levels ie 12.15 MJ (2900 kcal), 11.30 MJ (2700 kcal) and 10.48 MJ (2500 kcal) ME kg^?1 diet and two enzyme levels (0 and 0.5 g kg^?1 diet). A metabolism trial was conducted at the fourth week of age. At the end of week 5, 10 quails (five of each sex) per treatment were sacrificed for carcass characteristics and 20 female quails from each of the six dietary groups were housed in individual laying cages and fed respective layer diet to study the laying performance and egg quality up to 20 weeks of age. Body weight gains of quails fed 12.15 MJ or 11.30 MJ ME kg^?1 diets were significantly higher (p < 0.01) than those fed diets with 10.46 MJ ME kg^?1 diet. Feed intake was significantly lower (p < 0.01) in birds that received diet with 12.15 MJ ME kg^?1 than in birds that diets containing either 11.30 or 10.46 MJ ME kg^?1 diet. Feed conversion ratio (p < 0.01) was best at 12.15, followed by 11.30 and 10.46 MJ ME kg^?1 diet. Enzyme supplementation did not improve the growth performance, feed intake or feed conversion efficiency of quails. Enzyme addition also did not influence nitrogen retention or energy or dry matter metabolizability. The carcass characteristics did not differ because of energy or enzyme supplementation. Feed intake increased significantly (p < 0.01) as the dietary energy level decreased. The egg production and quality characteristics remained almost similar in all the dietary treatments. It was concluded that the optimum dietary energy level for quail was 12.15 MJ (2900 kcal) ME kg^?1 during the growing phase and 11.30 MJ (2700 kcal) ME kg^?1 during the laying phase. Addition of feed enzymes to conventional diets containing varying levels of maize, soyabean meal, fish meal and deoiled rice bran was not beneficial to improve growth, carcass traits, egg production performance or nutrient utilization. Copyright © 2004 Society of Chemical Industry     

Ferromagnetic resonance characterization of magnetostrictive metallic glass coatings

Amorphous ferromagnetic alloys are a promising class of materials that have been successfully used as magnetostrictive elements in fiber optic magnetic sensors. We have used ferromagnetic resonance (FMR) at about 9.5 GHz to characterize highly magnetostrictive film coatings of the amorphous ferromagnetic alloy Fe₈₁B_13.5Si_3.5C_2.R.f. sputtering was used to prepare films 0.1–0.6 μm thick on glass substrates and cladded single-mode optical fibers of diameter approximately 80 μm. Because of its inherent sensitivity, the FMR technique is shown to be an excellent non-destructive probe for investigating microscopic as well as macroscopic structural inhomogeneities that may arise from the fabrication process itself, subsequent handling or thermal aging of the coatings. An added advantage of the FMR technique is that it also allows a simultaneous measurement of such material parameters as the saturation magnetostriction coefficient, the saturation magnetization, the g factor and the uniaxial magnetic anisotropy energy. The effect of thermal annealing on some of these properties is also reported.     

High voltage electron microscope irradiation and observations in metallic glasses

High voltage electron microscope (hvem) has been extensively used to produce radiation damage and to study the characteristics of defects so produced in crystalline solids. To understand the defect production in metallic glasses and to evaluate the influence of such defects on physical properties like crystallisation temperature etc., high voltage microscopy and subsequentin situ heating and observation has been extremely useful technique. This paper gives a qualitative overview of such work performed in metallic glasses. In particular results obtained on a nickel based metallic glass using ahvem and an electron accelerator are presented. The advantages and limitations ofhvem irradiation are highlighted.