Asymptotically reliable serial production lines with a quality control system

A model of asymptotically reliable serial production lines with a quality control system is introduced. Its performance is analyzed in the case of a two machine, one buffer system.     

Modeling the Formation of Gas Bubbles inside the Pores of Reactive Electrochemical Membranes in the Process of the Anodic Oxidation of Organic Compounds

The use of reactive electrochemical membranes (REM) in flow-through mode during the anodic oxidation of organic compounds makes it possible to overcome the limitations of plate anodes: in the case of REM, the area of the electrochemically active surface is several orders of magnitude larger, and the delivery of organic compounds to the reaction zone is controlled by convective flow rather than diffusion. The main problem with REM is the formation of fouling and gas bubbles in the pores, which leads to a decrease in the efficiency of the process because the hydraulic resistance increases and the electrochemically active surface is shielded. This work aims to study the processes underlying the reduction in the efficiency of anodic oxidation, and in particular the formation of gas bubbles and the recharge of the REM pore surface at a current density exceeding the limiting kinetic value. We propose a simple one-dimensional non-stationary model of the transport of diluted species during the anodic oxidation of paracetamol using REM to describe the above effects. The processing of the experimental data was carried out. It was found that the absolute value of the zeta potential of the pore surface decreases with time, which leads to a decrease in the permeate flux due to a reduction in the electroosmotic flow. It was shown that in the solution that does not contain organic components, gas bubbles form faster and occupy a larger pore fraction than in the case of the presence of paracetamol; with an increase in the paracetamol concentration, the gas fraction decreases. This behavior is due to a decrease in the generation of oxygen during the recombination reaction of the hydroxyl radicals, which are consumed in the oxidation reaction of the organic compounds. Because the presence of bubbles increases the hydraulic resistance, the residence time of paracetamol—and consequently its degradation degree—increases, but the productivity goes down. The model has predictive power and, after simple calibration, can be used to predict the performance of REM anodic oxidation systems.     

Boron effects on the ductility of a nano-cluster-strengthened ferritic steel

The mechanical properties of Cu-rich nano-cluster-strengthened ferritic steels with and without boron doping were investigated. Tensile tests at room temperature in air showed that the B-doped ferritic steel has similar yield strength but a larger elongation than that without boron doping after extended aging at 500 °C. There are three mechanisms affecting the ductility and fracture of these steels: brittle cleavage fracture, week grain boundaries, and moisture-induced hydrogen embrittlement. Our study reveals that boron strengthens the grain boundary and suppresses the intergranular fracture. Furthermore, the moisture-induced embrittlement can be alleviated by surface coating with vacuum oil.     

Changes in expression of genes involved in apoptosis in activated human T-cells in response to modeled microgravity

Space flights result in remarkable effects on various physiological systems, including a decline in cellular immune functions. Previous studies have shown that exposure to microgravity, both true and modeled, can cause significant changes in numerous lymphocyte functions. The purpose of this study was to search for microgravity-sensitive genes, and specifically for apoptotic genes influenced by the microgravity environment and other genes related to immune response. The experiments were performed on anti-CD3 and IL-2 activated human T cells. To model microgravity conditions we have utilized the NASA rotating wall vessel bioreactor. Control lymphocytes were cultured in static 1g conditions. To assess gene expression we used DNA microarray chip technology. We had shown that multiple genes (approximately 3–8% of tested genes) respond to microgravity conditions by 1.5 and more fold change in expression. There is a significant variability in the response. However, a certain reproducible pattern in gene response could be identified. Among the genes showing reproducible changes in expression in modeled microgravity, several genes involved in apoptosis as well as in immune response were identified. These are IL-7 receptor, Granzyme B, Beta-3-endonexin, Apo2 ligand and STAT1. Possible functional consequences of these changes are discussed.     

How lean can lean buffers be?

This paper provides a quantitative characterization of the smallest, i.e., lean, buffer capacity necessary and sufficient to attain a desired throughput in serial production lines with identical exponential machines. The development is carried out in terms of normalized buffer capacity and production line efficiency. The smallest normalized buffer capacity required to ensure the desired line efficiency is referred to as the Lean Level of Buffering (LLB). Exact formulas for the LLB in two- and three-machine lines are presented and an approximate expression for the LLB in lines with more than three machines is derived. Along with these analytical results, several qualitative insights into the nature of lean buffering in serial production lines are presented.     

Microstructure and properties of Nb3Sn superconductors for the magnet system of the international thermonuclear experimental reactor

Results of a study of promising Nb₃Sn superconductors fabricated with the use of a bronze method and a method of internal source of tin for toroidal coils of the magnet system of the international thermonuclear experimental reactor (ITER) are presented. The main structural parameters and factors of the process of manufacturing technical superconductors based on Nb₃Sn, which determine the superconducting properties, are analyzed. The current-carrying capacity and the losses to hysteresis are determined for conductors with various diameters. The structure of the layer of superconducting Nb₃Sn compound is studied, and the relation between the structural parameters and the superconducting properties of the developed conductors is described. Examples of Nb₃Sn superconductors with a reinforcing element from a nanocomposite alloy Cu - 18% Nb are presented. Strength characteristics of the reinforced conductors are studied. Prospects of further enhancement of superconducting properties of Nb₃Sn superconductors obtained by both methods are estimated.     

Using microorganisms to process liquid radioactive wastes

Kurchatov Institute, Russian Scientific Center. Microbiology Institute, Russian Academy of Sciences. Translated from Atomnaya Énergiya, Vol. 74, No. 2, pp. 123-127, February, 1993.     

Transient behavior of serial production lines with Bernoulli machines

The steady-state performance of production systems with unreliable machines has been analyzed extensively during the last 50 years. In contrast, the transient behavior of these systems remains practically unexplored. Transient characteristics, however, may have significant manufacturing implications. Indeed, if, for example, transients are sluggish and the steady state is reached only after a relatively long settling time, the production system may lose some of its throughput, thus leading to a lower efficiency. This paper is devoted to analytical and numerical investigation of the transient behavior of serial production lines with machines having the Bernoulli reliability model. The transients of the states (i.e., the probabilities of buffer occupancy) are described by the Second Largest Eigenvalue (SLE) of the transition matrix of the associated Markov chain. The transients of the outputs (i.e., production rate, PR, and work-in-process, WIP) are characterized by both the SLE and Pre-Exponential Factors (PEF). We study SLE and PEF as functions of machine efficiency, buffer capacity and the number of machines in the system. In addition, we analyze the settling times of PR and WIP and show that the former is often much shorter than the latter. Finally, we investigate production losses due to transients and show that they may be significant in serial lines with relatively large buffers and many machines. To avoid these losses, it is suggested that all buffers initially be half full. For two- and three-machine lines these analyzes are carried out analytically; longer lines are investigated by simulations.     

Influence of Electroconvection on Chronopotentiograms of an Anion-Exchange Membrane in Solutions of Weak Polybasic Acid Salts

Visualization of electroconvective (EC) vortices at the undulated surface of an AMX anion-exchange membrane (Astom, Osaka, Japan) was carried out in parallel with the measurement of chronopotentiograms. Weak polybasic acid salts, including 0.02 M solutions of tartaric (NaHT), phosphoric (NaH₂PO₄), and citric (NaH₂Cit) acids salts, and NaCl were investigated. It was shown that, for a given current density normalized to the theoretical limiting current calculated by the Leveque equation (i/i_lim^theor), EC vortex zone thickness, d_EC, decreases in the order NaCl > NaHT > NaH₂PO₄ > NaH₂Cit. This order is inverse to the increase in the intensity of proton generation in the membrane systems under study. The higher the intensity of proton generation, the lower the electroconvection. This is due to the fact that protons released into the depleted solution reduce the space charge density, which is the driver of EC. In all studied systems, a region in chronopotentiograms between the rapid growth of the potential drop and the attainment of its stationary values corresponds to the appearance of EC vortex clusters. The amplitude of the potential drop oscillations in the chronopotentiograms is proportional to the size of the observed vortex clusters.