Impact of floating gate dry etching on erase characteristics in NOR flash memory

We report the effects of plasma process-induced damage during floating gate (FG) dry-etching process on the erase characteristics of NOR flash cells. As compared to flash cells processed in a stable plasma condition, it is found that flash cells processed in the nonoptimized ambient show significantly degraded erase characteristics under a negative gate Fowler-Nordheim (FN) bias, exhibiting a fast-erasing bit in the distribution of erased bits. However, little differences are found in their tunneling characteristics under a positive gate biasing. The gate bias polarity dependence of FN tunneling indicates that positive charges are created near the poly-Si/SiO/sub 2/ interface during the FG dry-etching, prior to the backend processes such as metal- or via-etch.     

The First Inert and Photostable Encapsulated Lanthanide(III) Complexes Based on Dendritic 9,10‐Diphenylanthracene Ligands: Synthesis,Strong Near‐Infrared Emission Enhancement,and Photophysical Studies

A series of inert and photostable encapsulated lanthanide(III) complexes—based on dendritic anthracene ligands—is shown for the first time to exhibit strong near‐IR emission bands via efficient energy transfer from the excited states of the peripheral antenna to the Ln³⁺ ions (Er³⁺, Yb³⁺, and Nd³⁺). A significant decrease in the fluorescence of the anthracene ligand is accompanied by a strong increase in the near‐IR emission of the Ln³⁺ ions. The near‐IR emission intensities of Ln³⁺ ions in the encapsulated Ln³⁺–dendrimer complexes are dramatically enhanced on increasing the generation number (n) of dendrons, owing to site‐isolation and light‐harvesting effects. Furthermore, a first attempt is made to distinguish between the site‐isolation and light‐harvesting effects in the present complexes. Photophysical studies indicate the sensitization of Ln³⁺ luminescence by energy transfer through the excited singlet state of the anthracene ligands, and the energy‐transfer efficiency between the dendritic anthracene ligands and the Ln³⁺ ion is evaluated to be in the range of 90 to 97 %. Their energy‐transfer efficiency is in good agreement with the result that the biexponential decays contain a radiative decay of anthracene units (< ca. 10 %) and an energy‐transfer component (> ca. 90 %) from the excited state of anthracene ligands to the Ln³⁺ ions. Time‐resolved luminescence spectra show monoexponential decays with a lifetime of 2 μs for the Er³⁺ ion 11 μs for the Yb³⁺ ion and 0.7 μs for the Nd³⁺ ion in thin films, and calculated intrinsic quantum yields of the Ln³⁺ ions are in the range of ca. 0.025 to 0.55 %.     

Experimental demonstration of enhancing pump absorption rate in cladding-pumped ytterbium-doped fiber lasers using pump-coupling long-period fiber gratings

A long-period fiber grating (LPFG) was inscribed in a single-mode fiber and was spliced with a ytterbium (Yb)-doped double-clad fiber in order to couple pump radiation of the inner cladding into the core in a cladding-pumped fiber laser. The use of an LPFG permits a partial core-pumping scheme in a cladding-pumping fiber laser because a portion of the pump radiation can be coupled to the core by LPFG. The enhancement of the pump absorption of a Yb-doped cladding-pumped fiber laser as the result of pump coupling by LPFG was 35%, and the maximal output power increased by up to 55% when a 20-W pump source is used.     

Different expression patterns of MMP-2 and MMP-9 in breast cancer

The role of nitric oxide (NO) in activation of cGMP is well established. It has been proposed that the ratio of cAMP to cGMP may be important in the regulation of preimplantation embryonic growth and differentiation. Therefore, we determined the ability of murine preimplantation embryos to produce NO. In addition, NO as an endogenous smooth muscle relaxant and vasodilator is a candidate for involvement in embryo implantation because this process requires increased vascular permeability and uterine quiescence at the sites of blastocyst apposition. Nitrite assays, an indirect measure of NO production, indicate that preimplantation murine embryos produce NO. This production was reversibly inhibited by culture of embryos in medium containing a nonspecific NO synthase (NOS) inhibitor (NG-nitro-L-arginine). Additionally, inhibition of normal development was observed in embryos cultured with NOS inhibitor. NO levels increased in culture medium when ovariectomized progesterone-treated animals were exposed to estrogen for 1 h in utero. Such hormonal treatment induces implantation. These data indicate that NO levels are regulated by estrogen and may be important in regulation of implantation. In addition, these data demonstrate for the first time that NO production appears to be required for normal embryonic development.     

Low-threshold narrow-linewidth InGaAs-GaAs ridge-waveguide DBR lasers with first-order surface gratings

The design and operation of InGaAs-GaAs ridge-waveguide distributed Bragg reflector (DBR) single quantum-well lasers with first-order surface gratings fabricated using only a single growth step are presented. Uncoated devices exhibit CW threshold currents as low as 6 mA with slope efficiencies of 0.46 W/A. By varying the period of the first-order DBR grating, a wavelength range of 540 /spl Aring/ (/spl sim/15.2 THz) is obtained with the threshold currents and slope efficiencies remaining below 10 mA and above 0.40 W/A, respectively, over the entire wavelength range. High characteristic temperature, T/sub 0/, values of 450 K, as measured between T=10/spl deg/C and 40/spl deg/C, are obtained for devices with Bragg wavelengths positively detuned from the peak gain wavelength. The spectral linewidth minimum of these devices is below 25 kHz, which is the resolution limit of the self-heterodyning system used to measure the spectral linewidth.     

Predictive model of a reduced surface field p-LDMOSFET using neural network

Due to complex dynamics, it has been extremely difficult to model high power devices. A predictive model is constructed by using a backpropagation neural network (BPNN). The BPNN was applied to predict electrical characteristics of a reduced surface field p-channel lateral double-diffused MOSFET. Drain–source currents for applied drain–source voltages were measured with a HP4156A. Prediction performance of BPNN model was optimized with variations in training factors. With respect to the reference models, the optimized models demonstrated considerably improved predictions. Model predictions were highly consistent with actual measurements. Further improvement was obtained by constructing a modular network comprising multiple BPNNs.     

Retrospective comparison of infusional 5-fluorouracil, doxorubicin, and mitomycin-C (modified FAM) combination chemotherapy versus palliative therapy in treatment of advanced gastric cancer

About one-third of patients with gastric cancer are unresectable at the time of diagnosis. Their median survival is < 6 months, with a grave prognosis. The purpose of this study was to assess the efficacy of a modified FAM (mFAM) regimen in advanced gastric cancer. We retrospectively reviewed the clinical records of 409 advanced gastric cancer patients who had not received curative surgery. Among 409 patients, 202 patients were treated with an mFAM regimen (infusional 5-FU + doxorubocin + mitomycin-C), and 207 patients received no chemotherapy (control group). No differences were found in clinical parameters between the two groups. The 1-year survival rates were 34.1% for the mFAM-treated group and 22.5% for the control group (p = 0.0135). In subset analysis, a higher 1-year survival rate was demonstrated in patients with mFAM and palliative surgery. Of the 154 evaluable patients in the mFAM-treated group, the response rate was 17.5%. In these patients, median response duration was 30 weeks, and progression-free survival was 23 weeks. Overall toxicity of mFAM regimen was relatively tolerable and reversible. In conclusion, FAM combination chemotherapy, which has been used as a standard therapy, prolonged survival after modification of the administration schedule and combination with palliative surgery. A prospective randomized study is warranted to confirm this conclusion from our retrospective study.     

Multilevel voltage wave-shaping display driver for AC plasma display panel application

A new sustainer circuit with multilevel voltage wave-shaping characteristics for an AC plasma display panel (AC-PDP) drive is proposed. The proposed circuit features half the device voltage stresses and significantly reduced power losses compared with those of the conventional ones. This circuit, realizable without much increased cost of the semiconductor devices, gives a significant improvement in the power efficiency, essential for the design of a drive circuit for the AC-PDP. A comparative analysis and experimental results are presented to show the validity of the proposed sustainer circuit.