Millisecond-order rapid micromixing with non-equilibrium electrokinetic phenomena

We report an active micromixer utilizing vortex generation due to non-equilibrium electrokinetics near micro/nanochannel interfaces. Its design is relatively simple, consisting of a U-shaped microchannel and a set of nanochannels. We fabricated the micromixer just using a two-step reactive ion etching process. We observed strong vortex generation in fluorescent microscopy experiments. The mixing performance was evident in a combined pressure-driven and electroosmotic flows, compared with the case with a pure pressure-driven flow. We characterized the micromixer for several conditions: different applied voltages, ion concentrations, flow rates, and nanochannel widths. The experimental results show that the mixing performance is better with a higher applied voltage, a lower ion concentration, and a wider nanochannel width. We quantified the mixing characteristics in terms of mixing time. The lowest mixing time was 2 milliseconds with the voltage of 230 V and potassium chloride solutions of 0.1 mM. We expect that the micromixer is beneficial in several applications requiring rapid mixing.     

燃气轮机在线状态建模与仿真研究

关于燃气轮机在线监测优化问题,状态监测对于燃气轮机的安全运行起着至关重要的作用。为了实现对燃机状态监测和性能评估的优化,应对燃机机组热力性能诊断、各部件性能精确预测。根据单轴燃气轮机的工作特点,进行系统建模,通过牛顿迭代法确定燃机各部件的共同工作点,实现对各种运行状态的监测和评估,并针对某型燃机编制了状态监测和性能评估软件进行仿真。结果表明,运算收敛速度较快,得到的结果与型燃机运行数据趋势基本一致,满足燃气轮机在线状态监测的需要,可以投入工程应用。     

信息化进程中计算机硬件学科建设的持续自主创新

目前,我国的信息产业也在不断的飞速发展,而信息化发展的进程中,计算机硬件学科也加入了其发展的行列,并长期以来一直坚持着可持续发展的自主创新理念。本文首先介绍了信息化的发展进程,接着分析了计算机硬件学科的建设的自主创新的坚持的主要原则,最后明确的阐述了计算机硬件学科,在建设的持续自主创新中采取的有利措施。     

纳米晶镁铝尖晶石透明微晶玻璃的晶化行为研究

利用DTA、XRD和TEM研究了制备工艺对微晶玻璃晶化行为的影响，并制备出具有纳米镁铝尖晶石为晶相的微晶玻璃。     

基于CPSO-BP神经网络的风电并网暂态电压稳定评估

针对目前传统方法难以快速、准确判断风电并网后系统暂态电压稳定性的问题,提出了一种基于CPSO-BP组合的风电并网暂态电压稳定评估方法。首先采用混沌理论对粒子群算法的不足进行改善,应用改进后的算法对神经网络的初始权值和阈值进行优化,然后利用系统故障前后采集的传统物理量和风电场相关的物理量作为BP神经网络输入特征量进行监督学习,最后将训练得到的模型应用于风电并网系统的暂态电压稳定评估中。利用英格兰10机39节点系统标准算例进行风电并网仿真分析,结果证明了所提方法的有效性。     

考虑多元可控负荷协调的配网鲁棒优化经济调度模型

为有效应对大规模分布式可再生能源和可控负荷接入配网后在经济优化调度方面所带来的挑战,本文建立考虑多元可控负荷协调的配网鲁棒优化经济调度模型.首先考虑电池储能系统、电动汽车及可参与需求侧管理的电负荷的能量转移特性,建立多元可控负荷可调模型;进而考虑配网中多元可控负荷的调峰能力及动态约束以运行成本最低建立配网鲁棒经济优化调度模型;最后,以蒙东某配网实际数据为例,在改进IEEE 14节点配电系统上进行调度仿真分析,验证本文所提出模型可充分利用多元可控负荷的调节能力,有效提升配网运行经济性.     

The GNAQ T96S Mutation Affects Cell Signaling and Enhances the Oncogenic Properties of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC), the most common malignant tumor in the liver, grows and metastasizes rapidly. Despite advances in treatment modalities, the five-year survival rate of HCC remains less than 30%. We sought genetic mutations that may affect the oncogenic properties of HCC, using The Cancer Genome Atlas (TCGA) data analysis. We found that the GNAQ T96S mutation (threonine 96 to serine alteration of the Gαq protein) was present in 12 out of 373 HCC patients (3.2%). To examine the effect of the GNAQ T96S mutation on HCC, we transfected the SK-Hep-1 cell line with the wild-type or the mutant GNAQ T96S expression vector. Transfection with the wild-type GNAQ expression vector enhanced anchorage-independent growth, migration, and the MAPK pathways in the SK-Hep-1 cells compared to control vector transfection. Moreover, cell proliferation, anchorage-independent growth, migration, and the MAPK pathways were further enhanced in the SK-Hep-1 cells transfected with the GNAQ T96S expression vector compared to the wild-type GNAQ-transfected cells. In silico structural analysis shows that the substitution of the GNAQ amino acid threonine 96 with a serine may destabilize the interaction between the regulator of G protein signaling (RGS) protein and GNAQ. This may reduce the inhibitory effect of RGS on GNAQ signaling, enhancing the GNAQ signaling pathway. Single nucleotide polymorphism (SNP) genotyping analysis for Korean HCC patients shows that the GNAQ T96S mutation was found in only one of the 456 patients (0.22%). Our data suggest that the GNAQ T96S hotspot mutation may play an oncogenic role in HCC by potentiating the GNAQ signal transduction pathway.     

从锌锗浸出液中提取锗的研究进展

锗资源开发对通讯和航空航天行业的发展具有重要的战略意义,由于提取锗的原料有限,所以开发和优化锗提取工艺受到日益关注.通过综述国内外从锌锗浸出液中提取锗的研究进展,对比多种锗的提取方法,总结出单宁沉锗法为应用最广泛的提锗方法.该方法具有绿色环保、操作简单的优点,但也存在单宁用量大,锗直收率低等问题亟待解决.基于超声波具有频率高、方向性好等优点,且已成功应用于湿法冶金工业中,因此进一步提出将超声外场引入单宁沉锗工艺中,并详细分析了超声外场强化的可行性和机理,以期降低单宁酸用量,提高锗直收率.指出超声外场强化单宁沉锗新工艺具有很好的研究和应用前景.     

电动车用永磁同步电机变频控制系统研究

为进一步达到电动车用高效率、宽调速范围的性能要求和高效节能的使用要求,提出电动车用永磁同步电机变频控制系统。结合永磁同步电机数学模型,分别对电动车用永磁同步电机变频控制系统进行硬件设计和软件设计。实验结果表明,永磁同步电机变频控制系统对于电动车用具有良好的适用性、可行性和一定的优势性。     

计及护层环流的电缆温升分析与故障定位方法研究

由于传统IEC热路法无法计算复杂工况下环流变化后电缆温度,因此,采用有限元法并结合电磁场与传热学原理,针对不同接地方式与运行工况下的三相电缆,计算与分析不同常见护层故障下环流变化后的电缆温升情况,为电缆运行状况判断提供参考。结果表明:对于护层交叉互联接地电缆,交叉互联箱进水地或护层接头故障后,故障相电缆温升高达10℃,且故障相电缆在故障点前后出现5℃的温差;对于护层单端接地电缆,发生两相护层故障后,故障点前段电缆较正常运行温升高达13℃以上,故障点前后段电缆存在10℃的温差;三相电缆温升及各相之间温差情况可为电缆温度在线监测提供参考,并根据电缆前后温差出现点对电缆故障点进行定位,尽快检修处理,从而减少后续击穿烧毁事故的发生。