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101.
González-Coloma A Reina M Medinaveitia A Guadaño A Santana O Martínez-Díaz R Ruiz-Mesía L Alva A Grandez M Díaz R Gavín JA De la Fuente G 《Journal of chemical ecology》2004,30(7):1393-1408
We have tested the insect antifeedant and toxic activity of 43 norditerpenoid alkaloids on Spodoptera littoralis and Leptinotarsa decemlineata including eserine (physostigmine), anabasine, and atropine. Antifeedant effects of the test compounds were structure- and species-dependent. The most active antifeedants to L. decemlineata were 1,14-diacetylcardiopetaline (9) and 18-hydroxy- 14-O-methylgadesine (33), followed by 8-O-methylconsolarine (12), 14-O-acetyldelectinine (27), karakoline (7), cardiopetaline (8), 18-O-demethylpubescenine (13), 14-O-acetyldeltatsine (18), takaosamine (21), ajadine (24), and 8-O-methylcolumbianine (6) (EC50 < 1 microg/cm2). This insect showed a moderate response to atropine. S. littoralis had the strongest antifeedant response to 24, 18, 14-O-acetyldelcosine (19), and delphatine (29) (EC50 < 3 microg/cm2). None of the model substances affected the feeding behavior of this insect. The most toxic compound to L. decemlineata was aconitine (1), followed by cardiopetalidine (10) (% mortality > 60), 14-deacetylpubescenine (14), 18-O-benzoyl-18-O-demethyl-14-O-deacetylpubescenine (17), 14-O-acetyldelcosine (19), 14-deacetylajadine (25) and methyllycaconitine (30) (% mortality > 45). Orally injected S. littoralis larvae were negatively affected by 1, cardiopetaline (8), 10, 1,14-O-acetylcardiopetalidina (11), 12, 14, 1,18-O-diacetyl-19-oxo-gigactonine (41), olivimine (43), and eserine in varying degrees. Their antifeedant or insecticidal potencies did not parallel their reported nAChR binding activity, but did correlate with the agonist/antagonist insecticidal/antifeedant model proposed for nicotininc insecticides. A few compounds [14, tuguaconitine (38), 14-demethyldelboxine (40), 19, dehydrodelsoline (36), 18-O-demethylpubescenine (13), 41, 9, and delcosine (23)] had selective cytotoxic effects to ward insect-derived Sf9 cells. None were cytotoxic to mammalian CHO cells and none increased Trypanosoma cruzi mortality. The selective cytotoxic effects of some structures indicate that they can act on biological targets other than neuroreceptors. 相似文献
102.
Experiments were performed to assess the reduction of Campylobacter spp. and Escherichia coli in commercial broiler carcasses by postchill dip applications of acidified sodium chlorite. Carcass rinses were collected before the inside-outside-bird washer (IOBW), post-IOBW, postchill, and after the postchill application of acidified sodium chlorite. Prevalence and counts of Campylobacter spp. and E. coli were determined. The mean values for Campylobacter spp. and E. coli counts differed significantly at sampling sites. The IOBW reduced the bacterial counts significantly in only one experiment. The chiller reduced Campylobacter counts significantly in both experiments but failed to significantly reduce the counts of E. coli in one experiment. No major reduction in the prevalence after enrichment for Campylobacter spp. was detected post-IOBW or postchill. However, a significant reduction in Campylobacter spp. and in E. coli counts and Campylobacter spp. prevalence was seen after the postchill application of acidified sodium chlorite. These results demonstrate that the antimicrobial effect of acidified sodium chlorite applied postchill may be used to significantly reduce Campylobacter spp. and E. coli in commercial broiler carcasses. Postchill systems may eventually be used in different applications, such as mist, spray, or bath, which could be applied closer to the final stages in processing. 相似文献
103.
Ismail Omar Hababeh Muthu Ramachandran Nicholas Bowring 《The Journal of supercomputing》2007,39(1):3-18
Enhancing the performance of the DDBs (Distributed Database system) can be done by speeding up the computation of the data allocation, leading to higher speed allocation decisions and resulting
in smaller data redundancy and shorter processing time. This paper deals with an integrated method for grouping the distributed
sites into clusters and customizing the database fragments allocation to the clusters and their sites. We design a high speed
clustering and allocating method to determine which fragments would be allocated to which cluster and site so as to maintain
data availability and a constant systemic reliability, and evaluate the performance achieved by this method and demonstrate
its efficiency by means of tabular and graphical representation. We tested our method over different network sites and found
it reduces the data transferred between the sites during the execution time, minimizes the communication cost needed for processing
applications, and handles the database queries and meets their future needs. 相似文献
104.
Compacts made from chemically grade Fe2O3 were fired at 1473K for 6 hrs. The fired compacts were isothermally reduced either by hydrogen or carbon monoxide at 1073–1373K. The O2 weight‐loss resulting from the reduction process was continuously recorded as a function of time using TGA technique, whereas the volume change at different reduction conditions was measured by displacement method. Porosity measurements, microscopic examination and X‐ray diffraction analysis were used to characterize the fired and reduced products. The rate of reduction at both the initial and final stages was increased with temperature. The reduction mechanism deduced from the correlations between apparent activation energy values, structure of partially reduced compacts and application of gas‐solid reaction models revealed the reduction rate (dr/dt) at both the initial and final stages. At early stages, the reduction was controlled by a combined effect of gaseous diffusion and interfacial chemical reaction mechanism, while at the final stages the interfacial chemical reaction was the rate determining step. In H2 reduction, maximum swelling (80%) was obtained at 1373K, which was attributed to the formation of metallic iron plates. In CO reduction, catastrophic swelling (255%) was obtained at 1198K due to the formation of metallic iron plates and whiskers. 相似文献
105.
106.
Omar Tahri Helder Araujo François Chaumette Youcef Mezouar 《Robotics and Autonomous Systems》2013,61(12):1588-1600
This paper deals with the use of invariant visual features for visual servoing. New features are proposed to control the 6 degrees of freedom of a robotic system with better linearizing properties and robustness to noise than the state of the art in image-based visual servoing. We show in this paper that by using these features the behavior of image-based visual servoing in task space can be significantly improved. Several experimental results are provided and validate our proposal. 相似文献
107.
In this paper, we address the problem of clustering in Vehicular Ad hoc Networks (VANETs) using Quality of Service Optimized Link State Routing (QoS-OLSR) protocol. Several clustering algorithms have been proposed for VANET and MANET. However, the mobility-based algorithms ignore the Quality of Service requirements that are important for VANET safety, emergency, and multimedia services while the QoS-based algorithms ignore the high speed mobility constraints since they are dedicated for Mobile Ad hoc Networks (MANETs). Our solution is a new QoS-based clustering algorithm that considers a tradeoff between QoS requirements and high speed mobility constraints. The goal is to form stable clusters and maintain the stability during communications and link failures while satisfying the Quality of Service requirements. This is achieved by: (1) considering the high mobility metrics while computing the QoS, (2) using Ant Colony Optimization for MPRs selection, and (3) using MPR recovery algorithm able to select alternatives and keep the network connected in case of link failures. Performance analysis and simulation results show that the proposed model can maintain the network stability, reduce the end-to-end delay, increase the packet delivery ratio, and reduce the communications overhead. 相似文献
108.
Sazia Parvin Farookh Khadeer Hussain Omar Khadeer Hussain Thandar Thein Jong Sou Park 《Computing》2013,95(10-11):927-948
With the rapid growth of wireless communication, the deployment of cyber-physical system (CPS) is increasing day by day. As a cyber physical system involves a tight coupling between the physical and computational components, it is critical to ensure that the system, apart from being secure, is available for both the cyber and physical processes. Traditional methods have generally been employed to defend an infrastructure system against physical threats. However, this does not guarantee that the availability of the system will always be high. In this paper, we propose a multi-cyber (computational unit) framework to improve the availability of CPS based on Markov model. We evaluate the effectiveness of our proposed framework in terms of availability, downtime, downtime cost and reliability of the CPS framework. 相似文献
109.
This chapter examines issues concerned with supporting managers and organizations with information and communication technologies
as they decide and act in turbulent and high-velocity environments. In particular, the chapter identifies five key tensions
in this context: (1) the tension between the need for quick decisions and the need for analytical decision processes; (2)
the tension involving managerial need for action and the need for the safest execution of decisions that may be bold and risky;
(3) the tension around empowering middle managers and management teams at various organizational levels in the midst of powerful
and impatient top executives; (4) the tension between programmed, quick-action learning loops and the increased requirement
for emergence and improvisation; and (5) the tension between expending effort to eliminate the digital divide with other organizations
versus finding expedient ways to communicate through heterogeneous digital infrastructures. Each of the tensions, and how
it can be managed, is illustrated through a case example. The chapter ends by suggesting that the management of these critical
tensions needs to be fused into the day-to-day fabric of management practices for decision support processes.
This article is part of the “Handbook on Decision Support Systems” edited by Frada Burstein and Clyde W. Holsapple (2008)
Springer. 相似文献
110.
Yifeng Lei Omar F. Zouani Lila Rami Christel Chanseau Marie‐Christine Durrieu 《Small (Weinheim an der Bergstrasse, Germany)》2013,9(7):1086-1095
How endothelial cells (ECs) express the particular filopodial or lamellipodial form of the actin machinery is critical to understanding EC functions such as angiogenesis and sprouting. It is not known how these mechanisms coordinately promote lumen formation of ECs. Here, adhesion molecules (RGD peptides) and inductor molecules (BMP‐2 mimetic peptides) are micropatterned onto polymer surfaces by a photolithographic technique to induce filopodial and lamellipodial migration modes. Firstly, the effects of peptide microgeometrical distribution on EC adhesion, orientation and morphogenesis are evaluated. Large micropatterns (100 μm) promote EC orientation without lumen formation, whereas small micropatterns (10–50 μm) elicit a collective cell organization and induce EC lumen formation, in the case of RGD peptides. Secondly, the correlation between EC actin machinery expression and EC self‐assembly into lumen formation is addressed. Only the filopodial migration mode (mimicked by RGD) but not lamellipodial migration mode (mimicked by BMP‐2) promotes EC lumen formation. This work gives a new concept for the design of biomaterials for tissue engineering and may provide new insight for angiogenesis inhibition on tumors. 相似文献