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排序方式: 共有307条查询结果,搜索用时 15 毫秒
51.
Yoshiaki Katada Akihiro Nishiguchi Kazuya Moriwaki Ryosuke Watakabe 《Artificial Life and Robotics》2016,21(3):295-301
One approach in swarm robotics is homogeneous system which is embedded with sensing, computing, mobile and communication components. In this study, a target detection problem, which is one of navigation problems, was employed. Once a robot detects a target, robots immediately communicate with a base station via intermediate relay robots due to the multi-hop transmission of wireless communication. Therefore, this control task is completed with connectivity of the network. In a target detection problem, we must improve the performance of exploration as well as connectivity of the network. This study investigates the performances of the two types of random walk algorithm in navigation while loosely ensuring connectivity of the robotic network based on our previous study. 相似文献
52.
Shiori Mori Rina Fujiwara-Tani Shingo Kishi Takamitsu Sasaki Hitoshi Ohmori Kei Goto Chie Nakashima Yukiko Nishiguchi Isao Kawahara Yi Luo Hiroki Kuniyasu 《International journal of molecular sciences》2021,22(15)
β-Casomorphin-7 (BCM) is a degradation product of β-casein, a milk component, and has been suggested to affect the immune system. However, its effect on mucosal immunity, especially anti-tumor immunity, in cancer-bearing individuals is not clear. We investigated the effects of BCM on lymphocytes using an in vitro system comprising mouse splenocytes, a mouse colorectal carcinogenesis model, and a mouse orthotopic colorectal cancer model. Treatment of mouse splenocytes with BCM in vitro reduced numbers of cluster of differentiation (CD) 20+ B cells, CD4+ T cells, and regulatory T cells (Tregs), and increased CD8+ T cells. Administration of BCM and the CD10 inhibitor thiorphan (TOP) to mice resulted in similar alterations in the lymphocyte subsets in the spleen and intestinal mucosa. BCM was degraded in a concentration- and time-dependent manner by the neutral endopeptidase CD10, and the formed BCM degradation product did not affect the lymphocyte counts. Furthermore, degradation was completely suppressed by TOP. In the azoxymethane mouse colorectal carcinogenesis model, the incidence of aberrant crypt foci, adenoma, and adenocarcinoma was reduced by co-treatment with BCM and TOP. Furthermore, when CT26 mouse colon cancer cells were inoculated into the cecum of syngeneic BALB/c mice and concurrently treated with BCM and TOP, infiltration of CD8+ T cells was promoted, and tumor growth and liver metastasis were suppressed. These results suggest that by suppressing the BCM degradation system, the anti-tumor effect of BCM is enhanced and it can suppress the development and progression of colorectal cancer. 相似文献
53.
Frame shuffling: a novel method for in vitro protein evolution 总被引:1,自引:0,他引:1
Kashiwagi K Isogai Y Nishiguchi K Shiba K 《Protein engineering, design & selection : PEDS》2006,19(3):135-140
We describe 'frame shuffling', a novel method for preparing artificial protein libraries. With this method, a Y-family DNA polymerase known to introduce frame shift mutations at high rates is utilized to scramble the reading frames of a parental gene. The resultant progeny produce mutant proteins having segmental sequence changes. Such frame-shuffled mutant proteins exhibit physicochemical properties that differ from those of proteins obtained using conventional mutagenesis. 相似文献
54.
Shuhei Nagayama Koichi Kajihara Kiyoshi Kanamura 《Materials Science and Engineering: B》2012,177(7):510-514
Silica glasses doped with LaF3 nanocrystals were prepared by HF-catalyzed sol–gel method. HF was used both as fluorine source and as catalyst of the sol–gel reaction, making it possible to shorten the processing time with reducing the concentration of SiOH groups to ~1018 cm?3. The resultant glasses are transparent at visible spectral range, and the optical loss at the ultraviolet absorption edge is dominated by the Rayleigh scattering from LaF3 crystallites. The size of LaF3 crystallites increases with an increase in the sintering temperature and time, and is smaller than ~40 nm in samples showing good visible transparency. Green upconversion photoluminescence is observed in an Er3+-doped sample under excitation at 980 nm. 相似文献
55.
Toshiisa Konishi Shuhei Takahashi Zhi Zhuang Kohei Nagata Minori Mizumoto Michiyo Honda Yasuhiro Takeuchi Hitomi Matsunari Hiroshi Nagashima Mamoru Aizawa 《Journal of materials science. Materials in medicine》2013,24(6):1383-1394
Novel biodegradable β-tricalcium phosphate (β-TCP) cements with anti-washout properties were created on the basis of chelate-setting mechanism of inositol phosphate (IP6) using β-TCP powders. The β-TCP powders were ball-milled using ZrO2 beads for 0–6 h in the IP6 solutions with concentrations from 0 to 10,000 ppm. The chelate-setting β-TCP cement with anti-washout property was successfully fabricated by mixing the β-TCP powder ball-milled in 3,000 ppm IP6 solution for 3 h and 2.5 mass% Na2HPO4 solution, and compressive strength of the cement was 13.4 ± 0.8 MPa. An in vivo study revealed that the above cement was directly in contact with host and newly formed bones without fibrous tissue layers, and was resorbed by osteoclast-like cells on the surface of the cement. The chelate-setting β-TCP cement with anti-washout property is promising for application as a novel injectable artificial bone with both biodegradability and osteoconductivity. 相似文献
56.
Takahiro Kozawa Hideya Hattori Shuhei Ogo Yusuke Ide Yoshikazu Suzuki 《Journal of Materials Science》2013,48(22):7969-7973
A simple and mild synthetic route via a hydrothermal treatment of Mg2TiO4 has been developed to prepare brookite-type TiO2. The hydrothermal conversion of Mg2TiO4 to brookite proceeded in 1 M HCl solution even at 100 °C. The converted brookite grains were composed of the angular particles covered on the textured surface, leaving the original morphology of Mg2TiO4 grains. Compared with the commercially available TiO2 catalysts (rutile, anatase, and P25), the brookite obtained in this study showed a good photocatalytic activity toward the oxidation of benzyl alcohol to benzaldehyde under a simulated sunlight irradiation. 相似文献
57.
58.
Shuhei Iwasaki Zen Satoh Houran Shafiee Akihiro Tagaya Yasuhiro Koike 《Polymer》2012,53(15):3287-3296
We designed and synthesized quaternary copolymers of methyl methacrylate (MMA), 2,2,2-trifluoroethyl methacrylate (TFEMA), benzyl methacrylate (BzMA), and 3,3,5-trimethylcyclohexyl methacrylate (TMCHMA) and we investigated their birefringence, thermal properties, and other optical properties. When the copolymer composition was MMA/TFEMA/BzMA/TMCHMA = 50:38:8:4, 40:30:7:23, or 30:21:7:42 (wt%), a zero–zero-birefringence polymer that exhibited neither orientational nor photoelastic birefringence was obtained. We demonstrated that such zero–zero-birefringence polymers with a variety of compositions could be successfully prepared in the quaternary system by using the same compensation method as applied in ternary random copolymerization. We also demonstrated that the glass-transition temperature (Tg) and refractive index (nD) of these copolymers could be controlled with high accuracy while retaining their zero–zero-birefringence property. We can therefore predict the type of birefringence, the Tg, and the nD of a particular copolymer before polymerization. Zero–zero-birefringence polymers with the most appropriate characteristics can then be synthesized selectively by quaternary copolymerization. 相似文献
59.
We have demonstrated the fabrication of two-dimensionally periodic non-close packed arrays of spherical polystyrene nanoparticles with controllable their structural parameters including diameter and interpartcile distance. The principle of this procedure relies on stepwise integration of spin-coat-assisted colloidal self-assembly of the single layer of close-packed polystyrene nanoparticle on a substrate, and subsequent etching of the particle under atmospheric pressure helium plasma. The plasma process converted the close-packed nanoparticle array into non-close-packed arrangement remaining with unchanged their original spherical shape and periodicity. Owing to the etching process underwent isotropically, the structural parameters could be controlled with nanometric accuracy by the treatment time. The etching rate strongly depended on the working pressure conditions, and the etching rate under 250 Torr was ca. 3 times faster than that of the 760 Torr. The effects of the working pressure indicated the neutral helium radicals and photons diffused from the plasma might be primarily responsible for the etching. 相似文献
60.
Miao‐miao Cheng Shuhei Kato Ryuichi Shimada 《IEEJ Transactions on Electrical and Electronic Engineering》2013,8(5):522-528
With increasing penetration of wind farms, power grids have responded by developing specific grid codes to maintain their stability. One of the main grid codes is the low‐voltage ride‐through (LVRT) capability, which requires the wind generator to remain connected when the grid voltage sags for a certain time period. A wind farm with squirrel cage induction generators suffers this LVRT problem the most because of their direct connection to the grid and reactive power consumption. In this paper, a new method is proposed to solve this problem by shunt‐connecting a motor‐driven mechanical load to the cage wind generator. For driving mechanical loads, the induction motor is most widely used in industries. This paper studies the terminal voltage holding effect of an induction machine during grid voltage sag due to the magnetic flux holding effect and the saturation characteristic. Taking advantage of this effect, the induction motor that is used for driving mechanical load is then proposed to improve the LVRT capability of wind turbine generators. Furthermore, the change of the rotating speed or slip of the induction machine is found to have a great impact on improving the LVRT. By adding some inertia to the motor‐driven mechanical load, an enhanced voltage holding effect, and therefore LVRT improvement, is expected for the wind farm. Both simulation and experimental results prove the effectiveness of the proposed method. © 2013 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc. 相似文献