全文获取类型
收费全文 | 816篇 |
免费 | 45篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 9篇 |
综合类 | 2篇 |
化学工业 | 420篇 |
金属工艺 | 13篇 |
机械仪表 | 15篇 |
建筑科学 | 28篇 |
矿业工程 | 1篇 |
能源动力 | 31篇 |
轻工业 | 105篇 |
水利工程 | 7篇 |
石油天然气 | 2篇 |
无线电 | 38篇 |
一般工业技术 | 97篇 |
冶金工业 | 27篇 |
原子能技术 | 1篇 |
自动化技术 | 66篇 |
出版年
2023年 | 16篇 |
2022年 | 86篇 |
2021年 | 101篇 |
2020年 | 15篇 |
2019年 | 22篇 |
2018年 | 25篇 |
2017年 | 24篇 |
2016年 | 39篇 |
2015年 | 42篇 |
2014年 | 36篇 |
2013年 | 58篇 |
2012年 | 45篇 |
2011年 | 57篇 |
2010年 | 37篇 |
2009年 | 45篇 |
2008年 | 37篇 |
2007年 | 36篇 |
2006年 | 21篇 |
2005年 | 22篇 |
2004年 | 18篇 |
2003年 | 15篇 |
2002年 | 15篇 |
2001年 | 10篇 |
2000年 | 4篇 |
1999年 | 7篇 |
1997年 | 4篇 |
1996年 | 2篇 |
1995年 | 1篇 |
1994年 | 5篇 |
1993年 | 2篇 |
1992年 | 2篇 |
1991年 | 1篇 |
1990年 | 1篇 |
1988年 | 1篇 |
1987年 | 2篇 |
1985年 | 1篇 |
1981年 | 1篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1974年 | 1篇 |
1973年 | 1篇 |
排序方式: 共有862条查询结果,搜索用时 9 毫秒
71.
The paper presents a new lossless ECG compression scheme. The short-term predictor and the coder use conditioning on a small number of contexts. The long-term prediction is based on an algorithm for R-R interval estimation. Several QRS detection algorithms are investigated to select a low complexity and reliable detection algorithm. The coding of prediction residuals uses primarily the Golomb-Rice (GR) codes, but, to improve the coding results, escape codes GR-ESC are used in some contexts for a limited number of samples. Experimental results indicate the good overall performance of the lossless ECG compression algorithms (reducing the storage needs from 12 to about 3-4 bits per sample). The scheme consistently outperforms other waveform or general purpose coding algorithms. 相似文献
72.
Organizations should look at humans as multilayered, not only as professional entities. In synergy, not only individually, we define humans as: (1) physical, (2) mental, (3) social, (4) spiritual, and (5) economic entities, marked by requisitely holistic patterns of relatively permanent characteristics, due to which individuals differ from each other; they differ also as specialized professionals. All these and other attributes form synergies. On this basis, the behavior of individuals who are willing to practice interdisciplinary cooperation becomes socially responsible and they have a high level of well-being.Individuals as well as organizations seek requisite personal holism (RPH) on the one hand and psychic well-being (PWB) on the other hand. Thus, individuals implement individual techniques and organizations implement special strategies, programs, and actions in the frame of human resource management (HRM). That is how organizations in the frame of HRM, more specifically in the frame of management well-being, are developing special programs for managing PWB. These programs are based on their RPH and organizations might help employees to feel respected and valued in their work settings, without regard to their culture, religion, ethnicity, gender, age, disability, or other individual differences. The most-often applied programs of the kind include: (1) stress management programs, (2) diversity management programs, (3) wellness programs, (4) employee assistance programs, and (5) programs for personal growth. 相似文献
73.
74.
Stefan M Marius S Hritcu L Lucian H Mihasan M Marius M Pricop D Daniela P Gostin I Irina G Olariu RI Romeo-Iulian O Dunca S Simona D Melnig V Viorel M 《Journal of materials science. Materials in medicine》2011,22(4):789-796
In the present study, we report enhanced antimicrobial properties of 29 and 23 nm silver nanoparticles (Ag NPs) obtained by
electrochemical synthesis in poly(amide-hydroxyurethane) media. Antibacterial activity assessed by disk diffusion method indicates
that silver nanoparticles produced inhibition zones for both Escherichia coli and Staphylococcus aureus depending on silver concentration. The bacterial growth curve performed in the presence of silver nanoparticles showed a
stronger antibacterial effect at lower concentrations than those described in the earlier reports. The effect was both dose
and size dependent and was more pronounced against Gram negative bacteria than Gram positive one. The smallest Ag NPs used
had a bactericidal effect resulting in killing E. coli cells. Scanning electron microscopy analysis indicated major damage and morphology changes of the silver nanoparticles treated
bacterial cells. The major mechanism responsible for the antibacterial effect probably consists in clusters formation and
nanoparticles anchorage to the bacterial cell surface. 相似文献
75.
76.
Mawase F Bar-Haim S Karniel A 《IEEE transactions on neural systems and rehabilitation engineering》2011,19(6):686-695
To date, research on the motor control of hand function in cerebral palsy has focused on children with hemiplegia, although many persons with diplegic cerebral palsy (dCP) have asymmetrically decreased hand function. We explored the predictive capabilities of the motor system in a simple motor task of lifting a series of virtual objects for five persons with spastic dCP and five age-matched controls. When a person lifts an object, s/he uses an expectation of the weight of the object to generate a motor command. We asked the study subjects to lift a series of increasing weights and determined whether they extrapolated from past experience to predict the next weight in the series, even though that weight had never been experienced. Planning of precision grasp was assessed by measurement of the grip force at the beginning of the lifting task and by estimating the motor command. Execution of precision grasp was assessed by measurement of the time interval between the onset of grip and the onset of movement. We found that persons with dCP demonstrated a lack of predictive feed-forward control in their lifting movements: they exhibited a significantly longer time between onset of grip and onset of movement than the control subjects and they did not predict the weight of the next object in the lifting task. In addition, for subjects with dCP, the time between the onset of grip and the onset of movement of the dominant hand correlated strongly with the outcome of a hand function test. We postulate that a higher-order motor planning deficit in addition to execution deficit are evident in the subjects with spastic diplegic. 相似文献
77.
Mihaela Ionescu Anca Pantea Stoian Manfredi Rizzo Dragos Serban Domenico Nuzzo Laura Mazilu Andra Iulia Suceveanu Ana Maria Dascalu Irinel Raluca Parepa 《International journal of molecular sciences》2021,22(21)
The 2019 novel coronavirus, known as severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) or coronavirus disease 2019 (COVID-19), is causing a global pandemic. The virus primarily affects the upper and lower respiratory tracts and raises the risk of a variety of non-pulmonary consequences, the most severe and possibly fatal of which are cardiovascular problems. Data show that almost one-third of the patients with a moderate or severe form of COVID-19 had preexisting cardiovascular comorbidities such as diabetes mellitus, obesity, hypertension, heart failure, or coronary artery disease. SARS-CoV2 causes hyper inflammation, hypoxia, apoptosis, and a renin–angiotensin system imbalance in a variety of cell types, primarily endothelial cells. Profound endothelial dysfunction associated with COVID-19 can be the cause of impaired organ perfusion that may generate acute myocardial injury, renal failure, and a procoagulant state resulting in thromboembolic events. We discuss the most recent results on the involvement of endothelial dysfunction in the pathogenesis of COVID-19 in patients with cardiometabolic diseases in this review. We also provide insights on treatments that may reduce the severity of this viral infection. 相似文献
78.
Maamoun Basheer Elias Saad Orly Laskar Ofir Schuster Hagai Rechnitzer Simona Zisman-Rozen David Azoulay Nimer Assy 《International journal of molecular sciences》2021,22(16)
Coronavirus disease (COVID-19) is a contagious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This case report presents a patient who had difficulty eradicating the corona virus due to being treated with Rituximab, which depletes B lymphocyte cells and therefore disables the production of neutralizing antibodies. The combined use of external anti-viral agents like convalescent plasma, IVIG and Remdesivir successfully helped the patient’s immune system to eradicate the virus without B-cell population recovery. In vitro studies showed that convalescent plasma is the main agent that helped in eradicating the virus. 相似文献
79.
Daniela Lisini Sara Lettieri Sara Nava Giulia Accordino Simona Frigerio Chandra Bortolotto Andrea Lancia Andrea Riccardo Filippi Francesco Agustoni Laura Pandolfi Davide Piloni Patrizia Comoli Angelo Guido Corsico Giulia Maria Stella 《International journal of molecular sciences》2021,22(16)
Malignant Pleural Mesothelioma (MPM) is a rare and aggressive neoplasm of the pleural mesothelium, mainly associated with asbestos exposure and still lacking effective therapies. Modern targeted biological strategies that have revolutionized the therapy of other solid tumors have not had success so far in the MPM. Combination immunotherapy might achieve better results over chemotherapy alone, but there is still a need for more effective therapeutic approaches. Based on the peculiar disease features of MPM, several strategies for local therapeutic delivery have been developed over the past years. The common rationale of these approaches is: (i) to reduce the risk of drug inactivation before reaching the target tumor cells; (ii) to increase the concentration of active drugs in the tumor micro-environment and their bioavailability; (iii) to reduce toxic effects on normal, non-transformed cells, because of much lower drug doses than those used for systemic chemotherapy. The complex interactions between drugs and the local immune-inflammatory micro-environment modulate the subsequent clinical response. In this perspective, the main interest is currently addressed to the development of local drug delivery platforms, both cell therapy and engineered nanotools. We here propose a review aimed at deep investigation of the biologic effects of the current local therapies for MPM, including cell therapies, and the mechanisms of interaction with the tumor micro-environment. 相似文献
80.
Benedetta Russo Marika Menduni Patrizia Borboni Fabiana Picconi Simona Frontoni 《International journal of molecular sciences》2021,22(10)
The role of the autonomic nervous system in obesity and insulin-resistant conditions has been largely explored. However, the exact mechanisms involved in this relation have not been completely elucidated yet, since most of these mechanisms display a bi-directional effect. Insulin-resistance, for instance, can be caused by sympathetic activation, but, in turn, the associated hyperinsulinemia can activate the sympathetic branch of the autonomic nervous system. The picture is made even more complex by the implicated neural, hormonal and nutritional mechanisms. Among them, leptin plays a pivotal role, being involved not only in appetite regulation and glucose homeostasis but also in energy expenditure. The purpose of this review is to offer a comprehensive view of the complex interplay between leptin and the central nervous system, providing further insights on the impact of autonomic nervous system balance on adipose tissue and insulin-resistance. Furthermore, the link between the circadian clock and leptin and its effect on metabolism and energy balance will be evaluated. 相似文献