Numerical methods for colorimetric calculations: Sampling density requirements

This article quantifies errors arising from various integration methods and from sampling density in the numerical estimation of colorimetric integrals, e.g., tristimulus values. Both data sampling density and various numerical integration method errors will be distinguished. A test is presented to quantify sampling interval requirements for accurate colorimetric calculations for various illuminants. © 1992 John Wiley & Sons, Inc.     

Psychology and war-avoidance: On Blight's blighted view.

Criticizes J. G. Blight's (see record 1987-16803-001) use of references, his identification with the policy of deterrence, his dismissal of approaches to reversing the nuclear arms race, and his discussion of a sociobiology of war. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

On the notion of granularity

Granularity is a well known concept in parallel processing. While intuitively, the distinction between coarse-grain and fine-grain paralellism is clear, there is no rigorous definition. This paper develops two notions of granularity, each defined formally and represented by a single rational number. The two notions are compared and contrasted with each other and with previously proposed definitions of granularity.Supported, in part, by NSA OCREAE Grant MDA904-85-H-0002. Currently on leave at the National Science Foundation.     

Interleukin-1 beta-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells

Increasing the susceptibility of tumor cells to apoptotic cell death following chemotherapy is of importance to the outcome of cancer treatment. Although the tumor suppressor gene p53 is required for efficient induction of apoptosis by chemotherapeutic agents, it is not the only apoptosis mediator gene. The molecular mechanisms mediating apoptosis following chemotherapy via p53-dependent or p53-independent pathways remain unclear. We show here that cis-diamminedichloroplatinum (cisplatin) induces the expression of interleukin-1 beta-converting enzyme (ICE), a mammalian homologue of the Caenorhabditis elegans cell death gene ced-3, in murine and human malignant glioma cells during apoptosis regardless of their p53 status. Furthermore, overexpression of the murine ICE gene induces apoptosis in these tumor cells. The apoptosis induced by cisplatin treatment or murine ICE overexpression can be suppressed by the tetrapeptide ICE inhibitor Ac-YVAD-CMK or the apoptosis inhibitors bcl-2 or bcl-2-related bcl-XL gene. These findings suggest that ICE may mediate apoptosis induced by chemotherapy, and its induction could represent a novel approach for the effective treatment of malignant glioma.     

Nqr experiments on Sc-Y alloys at very low temperatures

We have performed Nuclear Quadrupole Resonance (NQR) experiments on an alloy of scandium and yttrium. We find that the characteristic resonance frequencies in zero external field are 50 percent larger than in pure scandium. This increase in frequency makes the Sc-Y alloy a better candidate for absolute thermometry below 500 µK. However, the spin-lattice relaxation time of this alloy is more than an order of magnitude longer than in the pure scandium. In addition, we have observed an abrupt increase in the Korringa constant for temperatures below 5mK.     

Evaluation of refractive index approximations used for modedetermination in multiple quantum well slab waveguides

Approximations commonly used to determine the effective indexes of the guided modes of optical waveguides formed using multiple quantum well (MQW) materials are compared to the exact solutions in the slab waveguide model. Modeling the quantum well region as a single homogeneous layer with an average index of refraction is shown to produce results in close agreement with exact values of the effective index. A geometrically weighted average of the indexes provides the most accurate approximation for typical values of index and layer thickness of GaAs-Al_xGa_1-xAs quantum well waveguides