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11.
Multicasting applications such as multimedia conferencing, online multiplayer interactive games, and distance learning are becoming increasingly popular. With multiprotocol label switching, Internet protocol networks can offer quality of service and traffic engineering capabilities. This article introduces several approaches for multisource multicast sessions in the context of IP over WDM networks and evaluates their performance in terms of blocking probability, time complexity, and memory consumption. Our simulation study shows that among all the approaches, the newly proposed approach, known as one Bidirectional Tree with Just enough bandwidth reserved on each link of the tree, achieves the best overall performance. 相似文献
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Krizkova S Fabrik I Huska D Adam V Babula P Hrabeta J Eckschlager T Pochop P Darsova D Kukacka J Prusa R Trnkova L Kizek R 《International journal of molecular sciences》2010,11(12):4826-4842
The drugs based on platinum metals represent one of the oldest, but also one of the most effective groups of chemotherapeutic agents. Thanks to many clinical studies it is known that resistance of tumor cells to drugs is a frequent cause of chemotherapy failure. With regard to platinum based drugs, multidrug resistance can also be connected with increased expression of low-molecular weight protein metallothionein (MT). This study aimed at investigating the interactions of MT with cisplatin or carboplatin, using the adsorptive transfer technique coupled with differential pulse voltammetry Brdicka reaction (AdTS DPV Brdicka reaction), and a comparison of in vitro results with results obtained in vivo. The results obtained from the in vitro study show a strong affinity between platinum based drugs and MT. Further, we analyzed extracts of neuroblastoma cell lines treated with cisplatin or carboplatin. It is clear that neuroblastoma UKF-NB-4 cisplatin-resistant and cisplatin-sensitive cell lines unlikely respond to the presence of the platinum-based cytostatics cisplatin and carboplatin. Finally, we determined the level of MT in samples from rabbits treated with carboplatin and patients with retinoblastoma treated with the same drug. 相似文献
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The statistical properties of a radiation field (either Gaussian or laser) have been investigated by photon counting distributions. Two methods (nonlinear and linear) are here introduced and compared from the viewpoint of the accuracy of the measurement and of the associated information capacity. Finally, the method of the "joint photocount distributions" is here introduced as a new tool for the investigation of the time evolution of a random field. 相似文献
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Bhavesh D. Gajbhiye Sona C. S. Channamallikarjun S. Mathpati Ashwin W. Patwardhan Ananta Borgohain Naresh K. Maheshwari 《亚洲传热研究》2019,48(8):4354-4372
Molten salts have potential application as an efficient heat transfer medium in a primary and secondary heat exchanger in high temperature next‐generation nuclear power plant. Thermal hydraulic studies are vital for reliable and cost‐effective design of the nuclear power plant. Therefore heat transfer study of molten salts will play a vital role in this area. In this work, an experimental system was designed to study thermal hydraulics of the molten salt system up to 700°C. This work describes the pretest results of the experimental facility for extremely corrosive molten fluoride salts with a simulant thermia‐B as the working fluid. In the present work, the details of the system are discussed and thermal‐hydraulic data for heat transfer fluid thermia‐B has been presented. Experiments were carried out at Reynolds number in the range of 4500 to 40 500 and Prandtl number in the range of 34 to 144. Effect of Reynolds number, melting tank temperature, and heat input to test section on forced convective heat transfer was studied under turbulent conditions. Comparison of the experimental data with different empirical correlations has been presented. 相似文献
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Martina Culenova Andreas Nicodemou Zuzana Varchulova Novakova Michaela Debreova Veronika Smolinsk Sona Bernatova Dana Ivanisova Olga Novotna Jaromir Vasicek Ivan Varga Stanislav Ziaran Lubos Danisovic 《International journal of molecular sciences》2021,22(22)
Mesenchymal stem cells (MSCs) represent an attractive source within the field of tissue engineering. However, their harvesting often requires invasive medical procedures. Urine-derived stem cells (UDSCs) display similar properties to MSCs, and their obtention and further processing is non-invasive for the donors as well as low cost. Here, we offer a comprehensive analysis of their biological properties. The goal of this study was to analyze their morphology, stemness, differentiation potential and cytokine profile. We have successfully isolated UDSCs from 25 urine samples. First colonies emerged up to 9 days after the initial seeding. Cell doubling time was 45 ± 0.24 SD, and when seeded at the density of 100 cells/cm2, they formed 42 ± 6.5 SD colonies within 10 days. Morphological analyzes revealed that two different types of the cell populations have been present. The first type had a rice-grain shape and the second one was characterized by a polyhedral shape. In several cell cultures, dome-shaped cells were observed as well. All examined UDSCs expressed typical MSC-like surface markers, CD73, CD90 and CD105. Moreover, conditioned media from UDSCs were harvested, and cytokine profile has been evaluated showing a significantly higher secretory rate of IL-8, IL-6 and chemokines MCP-1 and GM-CSF. We have also successfully induced human UDSCs into chondrogenic, osteogenic and myogenic cell lineages. Our findings indicate that UDSCs might have immense potential in the regeneration of the damaged tissues. 相似文献