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排序方式: 共有344条查询结果,搜索用时 15 毫秒
61.
Majowicz SE McNab WB Sockett P Henson TS Doré K Edge VL Buffett MC Fazil A Read S McEwen S Stacey D Wilson JB 《Journal of food protection》2006,69(3):651-659
This study estimated the health burden and costs associated with gastroenteritis in the City of Hamilton (Ontario, Canada). The number of cases, number of different resource units used, and cost per resource unit were represented by probability distributions and point estimates. These were subsequently integrated in a stochastic model to estimate the overall burden and cost in the population and to depict the uncertainty of the estimates. The estimated mean annual cost per capita was Can dollar 115. The estimated mean annual cost per case was Can dollar 1,089 and was similar to other published figures. Gastroenteritis represented a significant burden in the study population, with costs high enough to justify prevention efforts. These results, currently the most accurate available estimates for a Canadian population, can inform future economic evaluations to determine the most cost effective measures for reducing the burden and cost of gastroenteritis in the community. 相似文献
62.
Kaltman Stacey; Green Bonnie L.; Mete Mihriye; Shara Nawar; Miranda Jeanne 《Canadian Metallurgical Quarterly》2010,2(1):31
Trauma exposure is frequently overlooked as a risk factor for psychiatric morbidity among studies with Latinos. The purpose of this study was to examine the relationships among trauma history, immigration-related factors, and mental health status among Latina immigrants. The current study used baseline data from a randomized clinical trial for the treatment of depression of 64 women with comorbid posttraumatic stress disorder and depression, 69 with depression-only, and 61 with no Axis I mental disorder. Sixty-four percent of the sample was Central American and 75% reported trauma exposure. Multinomial logit analysis suggested fewer years in the United States was associated with worse mental health status. Having a nonmarried marital status was also associated with worse mental health. Reporting four or more types of traumatic events was associated with an increase in the probability of comorbidity. These findings have important implications for future research and clinical practice. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
63.
Montpetit Mignon A.; Bergeman C. S.; Deboeck Pascal R.; Tiberio Stacey S.; Boker Steven M. 《Canadian Metallurgical Quarterly》2010,25(3):631
Resilience is often considered both a trait and a process. The current study proposes a new way to conceptualize resilience-as-process based on dynamical systems modeling, which allows researchers to capture the process of stress management in real time. Coupled damped linear oscillator models succinctly describe daily stress and negative affect in terms of developmental forces (e.g., velocity, acceleration). Models were fit to 56-day daily response data from 42 aging adults (Mage = 78.8 years; SDage = 6.6 years) to observe and understand linkages between daily stress and affect. It was speculated that individuals with greater resilience would experience stress as less coupled to changes in negative affect (less stress reactivity), and would recover their affective equilibrium more quickly following a given exogenous stressor (greater stress recovery). To identify resilience resources related to reliable interindividual differences in coupling and damping between stress and negative affect, we examined possible protective factors. Aspects of personality and social support predicted both the strength and nature of this coupling, such that higher levels of these resources resulted in greater protection from the cost to negative affect from stress, as observed in damping of negative affect and decreased coupling between systems. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
64.
A casein hydrolysate protects mice against high fat diet induced hyperglycemia by attenuating NLRP3 inflammasome‐mediated inflammation and improving insulin signaling 下载免费PDF全文
Niamh P. Healy Anna M. Kirwan Maeve A. McArdle Kieran Holohan Alice B. Nongonierma Deirdre Keane Stacey Kelly Lucia Celkova Claire L. Lyons Fiona C McGillicuddy Orla M Finucane Brian A. Murray Philip M. Kelly Lorraine Brennan Richard J. FitzGerald Helen M. Roche 《Molecular nutrition & food research》2016,60(11):2421-2432
65.
Li Z Knight S Cook LJ Hyde LK Holubkov R Olson LM 《Accident; analysis and prevention》2008,40(2):835-839
Motor vehicle crashes are a leading cause of death for young people in the United States. Assessing which drivers are at a high risk of experiencing a crash is important for the implementation of traffic regulations. Illegal street racing has been associated with a high rate of motor vehicle crashes. In this study, we link Utah statewide driver license citations and motor vehicle crash data to evaluate the rate of crashes for drivers with street racing citations relative to other drivers. Using a zero-inflated negative binomial model we found that drivers with no citations are approximately three times more likely to be at zero risk of a crash compared to drivers with street racing citations. Moreover, among drivers at non-negligible risk of crash, cited street racers are more likely to be involved in a crash compared to drivers without citations or those cited for violations other than street racing. However, drivers with increased numbers of non-street-racing citations experience crash risks approaching those of the cited street racers. 相似文献
66.
67.
Kronawitter CX Bakke JR Wheeler DA Wang WC Chang C Antoun BR Zhang JZ Guo J Bent SF Mao SS Vayssieres L 《Nano letters》2011,11(9):3855-3861
Direct experimental observation of spontaneous electron enrichment of metal d orbitals in a new transition metal oxide heterostructure with nanoscale dimensionality is reported. Aqueous chemical synthesis and vapor phase deposition are combined to fabricate oriented arrays of high-interfacial-area hetero-nanostructures comprised of titanium oxide and iron oxide nanomaterials. Synchrotron-based soft X-ray spectroscopy techniques with high spectral resolution are utilized to directly probe the titanium and oxygen orbital character of the interfacial region's occupied and unoccupied densities of states. These data demonstrate the interface to possess electrons in Ti 3d bands and an emergent degree of orbital hybridization that is absent in parent oxide reference crystals. The carrier dynamics of the hetero-nanostructures are studied by ultrafast transient absorption spectroscopy, which reveals the presence of a dense manifold of states, the relaxations from which exhibit multiple exponential decays whose magnitudes depend on their energetic positions within the electronic structure. 相似文献
68.
69.
Duff SB Scott EA Mafilios MS Todd EC Krilov LR Geddes AM Ackerman SJ 《Journal of food protection》2003,66(11):2103-2115
Foodborne illnesses impose a substantial economic and quality-of-life burden on society by way of acute morbidity and chronic sequelae. We developed an economic model to evaluate the potential cost-effectiveness of a disinfection program that targets high-risk food preparation activities in household kitchens. For the United States, Canada, and the United Kingdom, we used published literature and expert opinion to estimate the cost of the program (excluding the educational component); the number of cases of Salmonella, Campylobacter, and Escherichia coli O157:H7 infections prevented; and the economic and quality-of-life outcomes. In our primary analysis, the model estimated that approximately 80,000 infections could be prevented annually in U.S. households, resulting in 138 million dollars in direct medical cost savings (e.g., physician office visits and hospitalizations avoided), 15,845 quality-adjusted life-years (QALYs) gained, 788 million dollars in program costs, and a favorable cost-effectiveness ratio of 41,021 dollars/QALY gained. Results were similar for households in Canada and the United Kingdom (21,950 dollars Can/QALY gained and 86,341 pounds sterling/QALY gained, respectively). When we evaluated implementing the program only in U.S. households with high-risk members (those less than 5 years of age, greater than 65 years of age, or immunocompromised), the cost-effectiveness ratio was more favorable (10,163 dollars/QALY gained). Results were similar for high-risk households in Canada and the United Kingdom (1,915 dollars Can/QALY gained and 28,158 pounds sterling/QALY gained, respectively). Implementing a targeted disinfection program in household kitchens in the United States, Canada, and the United Kingdom appears to be a cost-effective strategy, falling within the range generally considered to warrant adoption and diffusion (<100,000 dollars/QALY gained). 相似文献
70.
Myers Catherine E.; DeLuca John; Schultheis Maria T.; Schnirman Geoffrey M.; Ermita Brandon R.; Diamond Bruce; Warren Stacey G.; Gluck Mark A. 《Canadian Metallurgical Quarterly》2001,115(3):560
Anterior communicating artery (ACoA) aneurysm rupture can lead to an anterograde amnesia syndrome similar to that observed after damage to the hippocampus and medial temporal lobes (MT). It is currently believed that ACoA amnesia results from basal forebrain damage that disrupts hippocampal processing without direct hippocampal damage. Converging evidence from animal studies and computational modeling suggests that qualitative differences may exist in the pattern of memory impairment after basal forebrain or MT damage. For example, animals with basal forebrain but not hippocampal damage are impaired at delay eyeblink classical conditioning (EBCC). In this study, individuals with ACoA amnesia were shown to be impaired at delay EBCC compared with matched controls; this contrasts with the spared delay EBCC previously observed in MT amnesia. This finding suggests the beginning of a possible dissociation between the memory impairments in MT versus ACoA amnesia. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献