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81.
P. Bruelemans P. Janssen K. D. Möller 《Journal of Infrared, Millimeter and Terahertz Waves》1996,17(1):51-59
The construction of a Fourier transform spectrometer to study magnetic resonances in solids is described. The spectrometer operates in the Far Infrared (maximum frequency of 500 cm?1) and is based on a wavefront dividing interferometer with circular geometry. To illustrate the performance, a water vapour spectrum is given. 相似文献
82.
MK Gutniak L Juntti-Berggren PM Hellstr?m A Guenifi JJ Holst S Efendic 《Canadian Metallurgical Quarterly》1996,19(8):857-863
OBJECTIVE: To investigate the acute effects of glibenclamide and glucagon-like peptide I (GLP-I) and their combination in perfused isolated rat pancreas and in patients with secondary failure to sulfonylureas. RESEARCH DESIGN AND METHODS: Rat islets were perfused with 10 nmol/l GLP-I in combination with 2 mumol/l glibenclamide. In human experiments, GLP-I (0.75 pmol. kg-1.min-1) was given as a continuous infusion during 240 min, while glibenclamide (3.5 mg) was administered orally. Eight patients participated in the study (age 57.6 +/- 2.7 years, BMI 28.7 +/- 1.5 kg/m2, mean +/- SE). In all subjects, blood glucose was first normalized by insulin infusion administered by an artificial pancreas (Biostator). RESULTS: GLP-I increased the insulinotropic effect of glibenclamide fourfold in the perfused rat pancreas. In human experiments, treatment with GLP-I alone and in combination with glibenclamide significantly decreased basal glucose levels (5.1 +/- 0.4 and 4.5 +/- 0.1 vs. 6.0 +/- 0.3 mmol/l, P < 0.01), while with only glibenclamide, glucose concentrations remained unchanged. GLP-I markedly decreased total integrated glucose response to the meal (353 +/- 60 vs. 724 +/- 91 mmol.l-1. min-1, area under the curve [AUC] [-30-180 min], P < 0.02), whereas glibenclamide had no effect (598 +/- 101 mmol.l-1. min-1, AUC [-30-180 min], NS). The combined treatment further enhanced the glucose lowering effect of GLP-I (138 +/- 24 mmol. l-1.min, AUC [-30-180 min], P < 0.001). GLP-I, glibenclamide, and combined treat-stimulated meal-induced insulin release as reflected by insulinogenic indexes (control 1.44 +/- 0.4; GLP-I 6.3 +/- 1.6, P < 0.01; glibenclamide 6.8 +/- 2.1, P < 0.01; combination 20.7 +/- 5.0, P < 0.001). GLP-I inhibited basal but not postprandial glucagon responses. Using paracetamol as a marker for gastric emptying rate of the test meal, treatment with GLP-I decreased gastric emptying at 180 min by approximately 50% compared with the control subjects (P < 0.01). CONCLUSIONS: In acute experiments on overweight patients with NIDDM, GLP-I exerted a marked antidiabetogenic action on the basal and postprandial state. The peptide stimulated insulin, suppressed basal glucagon release, and prolonged gastric emptying. The glucose-lowering effect of GLP-I was further enhanced by glibenclamide. This action may be at least partially accounted for by a synergistic effect of these two compounds on insulin release. Glibenclamide per se enhanced postprandial but not basal insulin release and exerted a less pronounced antidiabetogenic effect compared with GLP-I. 相似文献
83.
Three different techniques for measurement of plaque-pH--the sampling, the microtouch, and the telemetric methods--were compared after subjects had consumed different starch products. Ten volunteers, equipped with partial lower prostheses, incorporating a miniature glass pH electrode, refrained from toothbrushing for 3 days. Four products were tested: (1) soft bread, (2) potato chips, (3) 5% starch, and (4) 5% sucrose. The pH of plaque was measured for 45 min by means of all three of the methods. The results showed that the mean pH at 10 min was 1.5 units lower with the telemetric than with the sampling method and 1.0 unit lower with the telemetric than with the microtouch method. Relatively small differences were found among the effects of the four test products for all three methods, with the clearest distinctions among the pH curves being with the microtouch and telemetric methods. The main conclusions from the present investigation are: (1) that there were large differences in pH levels measured with the sampling, the microtouch, and the telemetric methods, even though they ranked the test products in about the same order, and (2) that the two starchy foods, bread and potato chips, were both easily fermented by dental plaque. 相似文献
84.
J Barreto J Liljestrand C Palha de Sousa S Bergstr?m B B?ttiger G Biberfeld F De la Cruz 《Canadian Metallurgical Quarterly》1993,25(6):685-688
The seroprevalence of HIV-1 and HIV-2 among pregnant women in Maputo, the capital of Mozambique, was compared between the years 1982/83, 1988 and 1990. None of the 432 serum samples collected in 1982/83 was positive for HIV antibodies whereas in 1988 the HIV-1 and HIV-2 seroprevalence was 0.4% (2/500) and 0.6% (3/500), respectively, and in 1990 0.6% (12/2014) and 0.2% (4/2014), respectively. These results indicate that HIV infection has been introduced recently in Maputo and is spreading at a slow rate among women. 相似文献
85.
86.
S. Brabetz R. Weidl F. Klemm L. Dörrer F. Schmidl P. Seidel 《Journal of Low Temperature Physics》1997,106(3-4):527-532
We investigated different types of high-Tc DC-SQUID gradiometers with the aim to develop an one-channel heart monitoring system for non-invasive measurements in unshielded
environment. This system could be used to obtain information about the patients condition in serial examinations and in emergency
cases fast and stable. Step-edge and bicrystal Josephson junctions were used to prepare planar galvanically coupled thin film
gradiometers and magnetometers. These sensors were used to carry out measurements in well-shielded and non-shielded environment
and we compared the different noise properties and field gradient resolutions. With different types and sizes of high-Tc DC-SQUID sensors magnetocardiograms were measured in a magnetically shielded room. The influence of antenna configurations,
SQUID parameters, and cooling conditions on the measurement of magnetocardiograms will be discussed. We investigated possibilities
to suppress the earth magnetic field (with pairs of Helmholtz coils) and for noise field compensation in unshielded environment. 相似文献
87.
88.
89.
M. Sanganeria D. T. Grider M. C. öztürk J. J. Wortman 《Journal of Electronic Materials》1992,21(1):61-64
In-situ doped polycrystalline SixGe1-x
(x = 0.7) alloys were deposited by rapid thermal chemical vapor deposition (RTCVD) using the reactive gases SiH2Cl2, GeH4 and B2H6 in a H2 carrier gas. The depositions were performed at a total pressure of 4.0 Torr and at temperatures 600° C, 650° C and 700° C
and different B2H6 flow rates. The conditions were chosen to achieve high doping levels in the deposited films. Our results indicate negligible
effect of B2H6 flow on the deposition rate. The depositions follow an Arrhenius type behavior with an activation energy of 25 kcal/mole.
Boron incorporation in the films was found to follow a simple kinetic model with higher boron levels at lower deposition rates
and higher B2H6 flow rates. As-deposited resistivities as low as 2 mΩ-cm were obtained. Rapid thermal annealing (RTA) in the temperature
range 800-1000° C was found to reduce the resistivity only marginally due to the high levels of boron activation achieved
during the deposition process. The results indicate that polycrystalline SixGe1-x films can be deposited by RTCVD with resistivities comparable to those reported for in-situ doped polysilicon. 相似文献
90.
Vergleich der Extrakte und des Lignins aus frischem und gelagertem Kiefernholz (Pinus sylvestris L.)
The degradation processes of the extractives of pine wood caused by aging are only noticeable in the heartwood. In seasoned sapwood the percentages of the water extracts and the cyclohexane-ethanol extract increase compared with the green sample; the alkali extracts, however, do not vary. The contents of acid lignin as well as the UV and IR spectra of MWL do not show differences. The amount of OCH3/C9 is in all samples 0.96, but the degree of oxidation is higher in the seasoned wood than in the green one. 相似文献