Antitumor, immunomodulatory and anti-HIV effect of mangiferin, a naturally occurring glucosylxanthone

We proposed previously a cyclic code made of 22 triplets, which we now call the AB code. It is made up of the following chain: AUGGUGCCAUUCAAGACUAUGA. The letters A, U, C, G represent the classical symbols of the (purine and pyrimidine) bases of the genetic code. This chain presents the following features: (1) when it is in cyclic form, it begins with the initiation codon AUG, ends with the termination codon UGA, and it can be read triplet after triplet by choosing 1 and only 1 representative of each synonymy class in the classical degenerate genetic code made of 64 triplets. The chain, therefore, possesses 1 and only 1 codon for each amino-acid; (2) except for the doublet CG, triplets of the chain begin with the 15 other possible doublets of bases (satisfying the "wobble" hypothesis presented by Crick); (3) it corresponds (except for 1 base) to the "loop" part of the CEnothera mitochondrial Gly-tRNA; (4) it can be modified, without loss of the properties (1) and (2), in such a way as to have 15 bases in common with the loop part of other mitochondrial tRNA's considered as primitive, like Ala-, Pro- and Arg-tRNA; (5) it contains the most frequent triplets, but not the most rare ones, appearing in the genome of numerous species; (6) it exhibits a coherent internal structure with respect to the molecular weight of its triplets. This structure, also found in the loop part of mitochondrial tRNA's, contains an excess of AU bases with respect to GC bases. This fact has no explanation in the classical probabilistic model of the tRNA's. Therefore, we propose the cyclic AB code as a primitive genetic structure with the essential coding properties of the present genetic code.     

An investigation of the origin of the main electron trap in GaAs

The origin of the main electron trap (0.83 eV) in GaAs is investigated by creating conditions to favour the formation of Ga-vacancy-oxygen complex in the material. Two specific schemes have been used, (1) Liquid phase epitaxial (LPE) growth of the material at high temperatures (≈1000°C) with oxygen doping and (2) Electron bombardment of LPE material and subsequent annealing. The traps have been characterised by transient capacitance technique. The results show that the main electron trap cannot be produced by either of the schemes thereby implying that a complex involving Ga-vacancy and oxygen may not be responsible for the trap.     

Analysis of steady-state characteristics of misaligned hydrodynamic journal bearings with isotropic roughness effect

The present work deals with the concept of a stochastic process to solve the problem of isotropic steady-state characteristics of hydrodynamic journal bearings of finite width, considering two types of misalignment, axial (vertical displacement) and twisting (horizontal displacement). Using a finite-difference method, the steady-state film pressures are obtained by solving a Reynolds type equation based on the principle of isotropic roughness pattern. With the help of the steady-state film pressures, the steady-state performance characteristics, in terms of load-carrying capacity, attitude angle, leakage flow-rate, friction coefficient and misalignment moment of a journal bearing with the slenderness ratio of unity, are obtained for various values of isotropic roughness parameter, eccentricity ratio and degree of misalignment.     

Linear stability analysis of hydrodynamic journal bearings under micropolar lubrication

The dynamic characteristics of hydrodynamic journal bearings lubricated with micropolar fluids are presented. The modified Reynolds equation is obtained using the micropolar lubrication theory. Applying the first order perturbation of the film thickness and steady state film pressure, the dynamic characteristics in terms of the components of stiffness and damping coefficients, critical mass parameter and whirl ratio are obtained with respect to the micropolar property for varying eccentricity ratios and slenderness ratios. The results show that micropolar fluid exhibits better stability in comparison with Newtonian fluid.     

Enhanced granulation by natural ionic polymer additives in UASB reactor treating low-strength wastewater

Effect of natural ionic polymer additives on granulation in lab-scale UASB reactors treating low-strength synthetic wastewater (COD 750-850 mg/L) was examined. The organic loading rate was 1.477+/-0.118 kgCOD/m3/day. Under identical conditions four similar reactors were operated in parallel with the following additives: control with no additive, anionic part of Reetha (Sapindus trifoliata) extract, cationic part of Reetha extract, and Chitosan. By the end of the study period, Chitosan as an additive produced largest granules with mean size of 0.15 mm closely followed by the cationic fraction of the Reetha extract with mean size of 0.144 mm, and anionic fractions of the Reetha extract with 0.139 mm. Control reactor with no additives had the smallest size granules with mean size of 0.128 mm. The fraction of granules in the sludge bed of size >0.1 mm showed similar trend. The largest granule size observed in the reactors with additives was 4-5mm as compared to 2 mm in the control reactor. Cationic polymers were more effective additives for enhancing sludge granulation. Exo-cellular protein, lipid, sugar and total polymer increased with granulation in the reactors. A COD removal efficiency of 95-98% was achieved in all the reactors.     

Phase equilibrium relations in the binary system Bi2O3-ZnO

Phase equilibria in the binary system Bi₂O₃-ZnO were studied by quenching technique. Heat-treated compositions were subjected to X-ray diffraction for phase identification, and differential thermal analysis, optical and scanning electron microscopy were used to determine the solid-liquid equilibria occurring in this system. The data thus obtained revealed that incorporation of a small amount of ZnO to the high-temperature face-centered cubic lattice of Bi₂O₃ leads to the formation of a body-centered cubic solid solution (-Bi₂O₃), which extends up to a composition of 2.2 mol% ZnO at a temperature near 750°C. On cooling, the -Bi₂O₃ solid solution undergoes a eutectoid transformation at a temperature of 710°C to yield the low-temperature monoclinic polymorph of Bi₂O₃ (-Bi₂O₃) and Bi₃₈ZnO₅₈. The eutectoid occurs at a composition of 1.8 mol% ZnO. The compound Bi₃₈ZnO₅₈ has a crystal structure analogous to the body-centered cubic -Bi₂O₃ solid solution and melts incongruently at a temperature near 753 ± 2°C to yield -Bi₂O₃ and liquid. A binary eutectic occurs between Bi₃₈ZnO₅₈ and ZnO at a composition near 25 ± 1.0 mol% ZnO with a melting temperature of 738 ±2°C. Based on the data obtained in this study, a revised phase diagram of the binary system Bi₂O₃-ZnO is proposed.     

Non-destructive evaluation of mechanical properties of poly (vinyl) alcohol-hydroxyapatite nanocomposites

Hydroxyapatite-poly (vinyl) alcohol nanocomposite powder was synthesized using varying poly (vinyl) alcohol concentrations. The dried powder was compacted into micro-porous disks at a load of 4 tons. The disks were sintered at 1200°C to evolve porous nanocomposites. Size and shape of the pores observed in the scanning electron micrographs were quantified by using image processing software. Ultrasound velocity measurements were done to evaluate mechanical properties non-destructively.     

A single variable shear deformable nonlocal theory for transversely loaded micro- and nano-scale rectangular beams

In this paper, a simple single variable shear deformable nonlocal theory for bending of micro- and nano-scale rectangular beams is presented. To incorporate small size effects, the theory uses Eringen’s nonlocal differential constitutive relations. The theory has only one fourth-order governing differential equation involving a single unknown variable. The governing equation and the expressions for the bending moment and shear force of the present theory are strikingly similar to those of nonlocal Euler-Bernoulli Beam Theory (EBT) formulated based on Eringen’s nonlocal elasticity theory. The theory assumes that the axial and lateral displacements have bending and shear components such that the bending components do not contribute towards shear force, and the shear components do not contribute towards bending moment. Also, the chosen displacement functions of the theory give rise to a realistic parabolic transverse shear stress distribution across the beam cross-section. Efficacy of the proposed theory is demonstrated through bending of simply supported, cantilever and clamped-clamped micro- and nano-scale beams of rectangular cross-section. The numerical results obtained by using the present theory are compared with those predicted by other nonlocal first-order and higher-order shear deformation beam theories. The results obtained are quite accurate.