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81.
以夹竹桃科植物止泻木子的干燥种子为原材料,采用乙醇提取法对其生物碱类物质进行粗提取,通过硅胶柱层析和重结晶技术对生物碱粗提物进行分离和纯化。利用核磁共振波谱和质谱法对其一种生物碱单体进行化学结构和分子量鉴定。实验结果表明,用70%乙醇在60℃条件下静止浸取3次,每次提取6 h,得到止泻木子总生物碱提取物,其得率达到0.244%。经过硅胶柱分离和重结晶纯化,可获得3种生物碱单体。对HPLC检测纯度达到94.89%的2号生物碱单体进行核磁共振波谱和质谱检测,得知该生物碱单体是一个分子量为356.59的锥丝碱(conessine)。该结果有利于了解以止泻木子为主要成分的蒙药药剂作用机理。 相似文献
82.
Takahiro Ohgoe Takafumi Suzuki Naoki Kawashima 《Journal of Low Temperature Physics》2013,171(3-4):309-314
By performing exact quantum Monte Carlo simulations, we study the momentum distribution of the supersolid state in the two-dimensional extended Bose-Hubbard model with the nearest-neighbor repulsion. For strong nearest-neighbor repulsions, the supersolid state is stable in a broad region up to large hopping amplitudes and high particle densities. In the supersolid state, the momentum distribution shows a bimodal structure with two peaks related to the superfluidity and solidity respectively. By our calculations, we show that the bimodal structure becomes clearer as the chemical potential (or the particle density) is increased. 相似文献
83.
Satoshi Ohara Tahereh Mousavand Takafumi Sasaki Mitsuo Umetsu Takashi Naka Tadafumi Adschiri 《Journal of Materials Science》2008,43(7):2393-2396
Continuous production of highly crystalline ZnO nanorods by supercritical hydrothermal synthesis was reported in this article.
Zinc nitrate aqueous solution was pressurized to 30 MPa at room temperature and rapidly heated to 673 K by mixing with supercritical
water and then fed into a tubular reactor. Residence time is about 10 s. Production of ZnO nanorod particles with uniform
particle size distribution showed a strong ultraviolet light emission at room temperature. This article also reported in-situ
surface modification of ZnO nanorods with organic reagents by the supercritical hydrothermal synthesis. 相似文献
84.
Jun Suzurikawa Takafumi Kinoshita Takenobu Inoue Mitsuhiro Kamo Norikazu Iida Kakuya Iwata Osamu Matsumoto 《IEEJ Transactions on Electrical and Electronic Engineering》2012,7(Z1):S184-S186
In order to improve direction stability of a power wheelchair on a cross‐sloped surface, a downhill turning prevention control (DTPC) has been developed by some researchers and wheelchair suppliers. The DTPC‐induced effect on wheelchair maneuver, however, has not been well clarified. In this study, we quantitatively assessed DTPC‐induced changes in joystick control strategies during a driving task on a cross‐sloped test course. Among several evaluation measures calculated from the joystick inputs during the test trials, the x‐axis joystick displacement amount was found to be significantly decreased by the DTPC. This result suggests that the DTPC can save wheelchair users from the burden of compensation control on cross‐sloped surfaces. © 2012 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc. 相似文献
85.
Pedestrian protection has played an important role for driver assistance systems.Our aim is to develop a video based driver assistance system for the detection of the potentially dangerous situation be... 相似文献
86.
87.
In the new century, energy and environmental problems are becoming more critical, and the development of natural energy is desired. Low-grade Thermal Energy Conversion (LTEC) is refocused as one of the renewable energy methods. The usefulness of LTEC is expected using hot springs and waste heat. In the case of the Rankine cycle using ammonia as the working fluid, the thermal properties of the working fluid changes in the evaporator. The traditional evaluation method of heat exchanger performance is the LMTD (Logarithmic Mean Temperature Difference) method. On the other hand, the GMTD (Generalized Mean Temperature Difference) method allows the variation of thermal properties in the heat exchanger. The aim of this study is to compare the two methods for the calculation of temperature differences and the corresponding influence on the total performance of the Rankine cycle that is operated using ammonia as a working fluid. As a result, the thermal efficiency of the Rankine cycle is greater than that of the LMTD method. Moreover, the computable range of the GMTD calcula- tion method is less than that of the LMTD calculation method. 相似文献
88.
Takahiro Kochi Masahito Shimizu Tomohiko Ohno Atsushi Baba Takafumi Sumi Masaya Kubota Yohei Shirakami Hisashi Tsurumi Takuji Tanaka Hisataka Moriwaki 《International journal of molecular sciences》2013,14(7):14700-14711
Metabolic syndrome is associated with an increased risk of colorectal cancer. This study investigated the impact of hypertension, a component of metabolic syndrome, on azoxymethane (AOM)-induced colorectal carcinogenesis using SHRSP/Izm (SHRSP) non-diabetic/hypertensive rats and SHRSP.Z-Leprfa/IzmDmcr (SHRSP-ZF) diabetic/hypertensive rats. Male 6-week-old SHRSP, SHRSP-ZF, and control non-diabetic/normotensive Wister Kyoto/Izm (WKY) rats were given 2 weekly intraperitoneal injections of AOM (20 mg/kg body weight). Two weeks after the last injection of AOM, the SHRSP and SHRSP-ZF rats became hypertensive compared to the control WKY rats. Serum levels of angiotensin-II, the active product of the renin-angiotensin system, were elevated in both SHRSP and SHRSP-ZF rats, but only the SHRSP-ZF rats developed insulin resistance, dyslipidemia, and hyperleptinemia and exhibited an increase in adipose tissue. The development of AOM-induced colonic preneoplastic lesions and aberrant crypts foci, was significantly accelerated in both SHRSP and SHRSP-ZF hypertensive rats, compared to WKY normotensive rats. Furthermore, induction of oxidative stress and exacerbation of inflammation were observed in the colonic mucosa and systemically in SHRSP and SHRSP-ZF rats. Our findings suggest that hypertension plays a role in the early stage of colorectal carcinogenesis by inducing oxidative stress and chronic inflammation, which might be associated with activation of the renin-angiotensin system. 相似文献
89.
Nusrat J. M. Sanghamitra Hiroshi Inaba Susumu Kitagawa Takafumi Ueno 《Journal of Inorganic and Organometallic Polymers and Materials》2013,23(1):50-60
In the last decade, there has been great deal of progress in the study of self-assembly processes of protein assemblies as biotemplates to create and construct one-dimensional arrays of nanocrystalline metals and semiconductors. Successful attempts in fabricating the protein-based bioelectronics could serve as a promising alternative to synthetic template based nanomaterials. Another perspective of protein assemblies is its use in the field of tissue engineering either as scaffold for cell adhesion and proliferation or as a foreign (bio)nanofunctionality to communicate with the macromolecules present in the extracellular or intracellular milieu and participate in the precise control of vital cell functions. Three-dimensionally arranged protein monomers to form bionanotubes are promising in terms of innate biocompatibility, easy bio-conjugation to incorporate multiple functionalities and well-defined nano-scale lengths. Such unique chemical properties of protein assemblies are described in this review. 相似文献
90.
Shusuke Nakajima Hiroaki Matsuhashi Hidenori Higashi Takafumi Seto Yoshio Otani 《Aerosol science and technology》2013,47(10):959-965
Air filters collect particles by the mechanical collection mechanisms, namely, inertia, interception, gravitational settling, and Brownian diffusion. There exists the most penetrating particle size (MPPS) in submicron size range for which none of the collection mechanisms work effectively. In this study, we propose a new type of filter named as “centrifugal filter,” which collects aerosol particles by centrifugal force together with the conventional mechanical collection mechanisms. The centrifugal filter proposed in the present work may be rotated by a motor or compressed air. Air passes through the filter in the axial direction of filter rotation. The filter rotates so does the air embedded in the filter, and therefore centrifugal force exerts on particles. In addition to the mechanical collection mechanisms, small migration of particles due to the centrifugal force enhanced the collection efficiency of submicron particles significantly without increasing the pressure drop. The performance tests of centrifugal filter were conducted by changing the fiber diameter, the air flow velocity and the rotation speed. We found that the collection efficiency of filter is enhanced significantly by rotating the filter without increasing the pressure drop and that the filter efficiency is well predicted by the conventional filtration theory accounting for the centrifugal force.Copyright 2015 American Association for Aerosol Research 相似文献