Characterization of alternative plasticizers in poly(vinyl chloride) sheets for blood containers

This study aimed to optimize the ratio of dioctyl 4‐cyclohexene‐1,2‐dicarboxylate (DOTH) and di‐isononyl‐cyclohexane‐1,2‐dicarboxylate (DINCH^®) for use as plasticizers in poly(vinyl chloride) (PVC) sheets. We also evaluated the biological safety of DOTH for its potential to be part of a safe PVC‐based blood container. The suppression of hemolysis in mannitol‐adenine‐phosphate / red cell concentrates (MAP/RCC) with DOTH/(DINCH^®‐PVC) sheets and the elution of plasticizers from the sheets increased with higher DOTH compositions. The properties of the PVC sheet containing DOTH and DINCH^® in the ratio of 25:33 parts against PVC 100 parts as a weight were almost identical to the PVC sheet made of di(2‐ethylhexyl) phthalate. From a subchronic toxicity test, DOTH did not show any adverse effects on all organs, including the testes, epididymis, liver, and kidneys. The no‐observed‐adverse‐effect level was 300 mg/kg body weight/day in a rat. These results suggest that DOTH/DINCH^® (25:33) is a promising candidate for the replacement of di(2‐ethylhexyl) phthalate in blood containers. J. VINYL ADDIT. TECHNOL., 22:520–528, 2016. © 2015 Society of Plastics Engineers     

Analysis of enoyl-coenzyme A hydratase activity and its stereospecificity using high-performance liquid chromatography equipped with chiral separation column

Enoyl-coenzyme A (CoA) hydratase catalyzes the hydration of trans-2-enoyl-CoA to yield 3-hydroxyacyl-CoA during fatty acid degradation (β-oxidation). Although much research has focused on the stereospecificities of 2-enoyl-CoA hydratases, a direct quantification of the production of 3(R)- and 3(S)-hydroxyacyl-CoA has not yet been established. Therefore, we developed a method of concurrently quantifying 3(R)- and 3(S)-hydroxyacyl-CoA using high-performance liquid chromatography (HPLC) equipped with a chiral separation column. The optimized conditions for the separation of 3(R)-, 3(S)-hydroxyhexadecanoyl-CoA and trans-2-hexadecenoyl-CoA, were determined to be as follows: mobile phase of 35/65 (v/v) of 50 mM phosphate buffer (pH 5.0)/methanol; flow rate of 0.5 mL/min; detection at 260 nm; and column temperature of 25°C. This method was applied to subcellular fractions of rat liver; the results directly confirmed that 3(S)-hydroxyhexadecanoyl-CoA is the dominant product obtained from the heat-stable enoyl-CoA hydratase-catalyzed reaction of trans-2-hexadecenoyl-CoA. Finally, the stereospecificities of L-bifunctional protein (L-BP) and D-bifunctional protein (D-BP) were reinvestigated using this method, and it was confirmed that L- and D-BP yielded 3(S)- and 3(R)-hydroxyhexadecanoyl-CoA were yielded from trans-2-hexadecenoyl-CoA, respectively. 3(R)-Hydroxyacyl-CoA is a peroxisomal β-oxidation-specific intermediate. Therefore, this method is potentially useful not only studies regarding the stereochemistry of enoyl-CoA hydratase but also for the diagnosis of diseases caused by defects of peroxisomal enoyl-CoA hydratase.     

Photoinduced Formation of Small Gold Particles in Silica Gels

AuCl⁻₄ ions in sol-gel-derived silica gels (Au/silica gels) were photoreduced by ultraviolet light irradiation at room temperature. In the presence of ethylene glycol in the silica gels, small Au particles were effectively formed by the irradiation. When the storage temperature of the gels was increased in the dark after the irradiation, the surface plas-mon resonance absorption peak of the Au particles was shifted to longer wavelengths, indicating that the Au particles became large. At a storage temperature below 9°C, Au particles could not be observed in the silica gels. The apparent activation energy of Au particle formation was estimated to be 17. 3 kcal·tmol⁻¹.     

Polynomial Approximations Describing Rate of Dyeing from a Finite Bath

Three polynomial approximations to Wilson's equation were derived by means of Hastings's method. One of them is an approximation to Crank's equation with 3–figure accuracy and it approximates to Wilson's epuation very closely for high values of fractional equilibrium exhaustion (E), E > 0. 95. Two other polynomials approximate to Wilson's equation very well in the ranges 0. 95 > EX). 76 and 0. 76 > E > 0. 30 respectively. The polynomials derived here only include up to second order terms, so that by using the equations which are obtained by solving the polynomials for diffusion coefficient (D), D can easily be calculated from experimental dye uptake data. By using the polynomial approximation, the changes in rate–of–dyeing of a non–ionic dye on a nylon 6 fibre by addition of a dispersing agent were calculated. Results of the experiment agreed well with the calculated.     

Non-degenerate Linear Codes Determined by their Weight Enumerators

 In [1], Homma-Kim-Yoo showed that a code C such that the support of the associated projective system is a union of two linear subspaces, is uniquely determined up to equivalence by its weight enumerator. Let W _C (z) be the weight enumerator of a code C. Assuming certain conditions on the coefficients of W _C (z) for some range, we prove that the support of the associated projective system is a union of two linear subspaces. Received: February 27, 2002; revised version: October 2, 2002 Keywords: Linear code, Projective system, Weight enumerator. MSC2000: 94B27, 94B65, 51E20 Partially supported by Grant-in-Aid for Scientific Research, Ministry of Education, #12640180     

Dielectric Depression and Dispersion in Electrophoretically Fabricated BaTiO3 Ceramic Films

Dielectric depression and dispersion were observed in BaTiO3 ceramic films fabricated by electrophoretic deposition followed by sintering. The dielectric constants were depressed down to 6800–4600 around the Curie point ( T _C ). The dielectric dispersion occurred above T _C . These dielectric properties are attributable to a surface layer formed during sintering. XRD analysis indicated that the surface layer was a hexagonal-like BaTiO₃ phase. A mixed solvent of acetylacetone and alcohol employed in the present work may have been responsible for the formation of the surface layer.     

Analytical investigation of two different absorption modes: falling film and bubble types

The objectives of this paper are to analyze a combined heat and mass transfer for an ammonia–water absorption process, and to carry out the parametric analysis to evaluate the effects of important variables such as heat and mass transfer areas on the absorption rate for two different absorption modes — falling film and bubble modes. A plate heat exchanger with an offset strip fin (OSF) in the coolant side was used to design the falling film and the bubble absorber. It was found that the local absorption rate of the bubble mode was always higher than that of the falling film model leading to about 48.7% smaller size of the heat exchanger than the falling film mode. For the falling film absorption mode, mass transfer resistance was dominant in the liquid flow while both heat and mass transfer resistances were considerable in the vapor flow. For the bubble absorption mode, mass transfer resistance was dominant in the liquid flow while heat transfer resistance was dominant in the vapor region. Heat transfer coefficients had a more significant effect on the heat exchanger size (absorption rate) in the falling film mode than in the bubble mode, while mass transfer coefficients had a more significant effect in the bubble mode than in the falling film mode.     

Risk hedging against the fuel price fluctuation in energy service business

Energy service business, or energy service company (ESCO), is expanding among industrial users as a means of energy saving. The ESCO business normally tends to become a long-term operation. During the operation, fluctuations of fuel and electricity costs significantly impact on the stability of the profit from ESCO business. Therefore, it is essential to reduce the risk of fuel and electricity cost fluctuations. Generally, a transaction called “financial derivative” is used as a measure of hedging against the fuel price fluctuation. In the case of ESCO business, it is necessary to manage the risk of both electricity and fuel price fluctuations because the variation in electricity price strongly affects the profit from ESCO as that in fuel price does.     

Environmental stress cracking of poly(acrylonitrile-butadiene-styrene)

The environmental stress cracking (ESC) of acrylonitrile-butadiene-styrene (ABS) copolymer caused by a non-ionic surfactant (poly-oxyethylene alkylether) was studied by constant-load tensile creep tests and edge crack tension (ECT) tests. The fracture surfaces were investigated by a scanning electron microscope (SEM) and the morphology of the crack tip was investigated by a transmission electron microscope (TEM). It was found that the results of the creep tests performed in the non-ionic surfactant were very different from those performed in air. SEM images of the fracture surfaces showed that there were three different mechanisms of fracture and that specimens had a tendency to rupture by ESC when the stress was small. The results of the ECT tests and the TEM images showed that the change in the mechanism of the fracture was attributable to the change of morphology at the crack tip.