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21.
Huimin Zhang Le Xie Sen Chen Yue Qiu Yu Sun Weijia Kong 《International journal of molecular sciences》2022,23(21)
Different serum thyroxine levels may influence the morphology of the inner ear during development. A well-developed organ of Corti (OC) is considered to be critical to the function of hearing. In our study, we treated mice with triiodothyronine (T3) and found that the opening of the OC occurred sooner than in control mice. We also observed an increased formation of acetylated microtubules and a decrease in the adhesion junction molecule P-cadherin the during opening of the OC. Our investigation indicates that thyroxin affects P-cadherin expression and microtubule acetylation to influence the opening of the OC. 相似文献
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Binwen Tan Miaomiao Wang Li Cai Sanyue Li Wei Zhu Lili Xu Yi Wang Jian Zeng Xing Fan Lina Sha Dandan Wu Yiran Cheng Haiqin Zhang Guoyue Chen Yonghong Zhou Houyang Kang 《International journal of molecular sciences》2022,23(18)
Powdery mildew caused by Blumeria graminis f. sp. tritici is a devastating disease that reduces wheat yield and quality worldwide. The exploration and utilization of new resistance genes from wild wheat relatives is the most effective strategy against this disease. Psathyrostachys huashanica Keng f. ex P. C. Kuo (2n = 2x = 14, NsNs) is an important tertiary gene donor with multiple valuable traits for wheat genetic improvement, especially disease resistance. In this study, we developed and identified a new wheat—P. huashanica disomic addition line, 18-1-5—derived from a cross between P. huashanica and common wheat lines Chinese Spring and CSph2b. Sequential genomic and multicolor fluorescence in situ hybridization analyses revealed that 18-1-5 harbored 21 pairs of wheat chromosomes plus a pair of alien Ns chromosomes. Non-denaturing fluorescence in situ hybridization and molecular marker analyses further demonstrated that the alien chromosomes were derived from chromosome 7Ns of P. huashanica. The assessment of powdery mildew response revealed that line 18-1-5 was highly resistant at the adult stage to powdery mildew pathogens prevalent in China. The evaluation of agronomic traits indicated that 18-1-5 had a significantly reduced plant height and an increased kernel length compared with its wheat parents. Using genotyping-by-sequencing technology, we developed 118 PCR-based markers specifically for chromosome 7Ns of P. huashanica and found that 26 of these markers could be used to distinguish the genomes of P. huashanica and other wheat-related species. Line 18-1-5 can therefore serve as a promising bridging parent for wheat disease resistance breeding. These markers should be conducive for the rapid, precise detection of P. huashanica chromosomes and chromosomal segments carrying Pm resistance gene(s) during marker-assisted breeding and for the investigation of genetic differences and phylogenetic relationships among diverse Ns genomes and other closely related ones. 相似文献
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路面结冰易于导致交通事故的发生,因此提出一种路面暖气垫融冰法。为了获得最佳的融冰效果,以固定体积暖气垫为研究对象,将暖气垫工作表面的融冰速率和融冰均匀度作为评估指标,以暖气垫长度、厚度和通路间距为优化参数,通过热流场仿真分析,采用均匀设计响应面法得到优化目标与结构参数间的函数关系,运用遗传算法进行多目标优化得到非劣解集,采用理想点法TOPSIS从中选出最优解,得出结论:当通路直径取20 mm时,最佳参数组合为通路间距48 mm、暖气垫厚度68 mm,横向边长可根据工程应用确定。 相似文献
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Phase measuring deflectometry (PMD) is a robust, noncoherent technique for the characterization of specular surface. For measuring high specular reflectivity surface, PMD can deliver micron radian range local gradient. However, when the measured surface has low specular reflectivity, the accuracy of the measured gradient is low since the captured fringe pattern shows low signal to noise ratio. The phase error characteristics in PMD system when testing low reflectivity surfaces are analyzed. The analysis illustrates that the random phase error increases rapidly while the nonlinear error drops slowly with the decreasing of the tested surface reflectivity. In order to attain high precision measurement of low reflectivity specular surface, a robust error reduction method based on wavelet de-noising is proposed to reduce the phase error. This error reduction method is compared with several other normally used methods in both simulation and experiment work. The method based on the wavelet de-noising shows better performance when measuring the low reflectivity specular surface. 相似文献
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XML的迅猛发展使得对XML更新语言的需求进一步地增强,XML更新语言已成为一个新的研究热点.面向对象的XML-RL更新语言的设计支持具有面向对象特征的XML更新.首先介绍面向对象XML-RL更新语言,其次论述了逻辑操作符和物理操作符的设计思想与具体实现算法. 相似文献
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Tianhao Wu Zhenzhen Qin Yanbo Wang Yongzhen Wu Wei Chen Shufang Zhang Molang Cai Songyuan Dai Jing Zhang Jian Liu Zhongmin Zhou Xiao Liu Hiroshi Segawa Hairen Tan Qunwei Tang Junfeng Fang Yaowen Li Liming Ding Zhijun Ning Yabing Qi Yiqiang Zhang Liyuan Han 《纳微快报(英文)》2021,(10):113-130
Perovskite solar cells (PSCs) emerging as a promising photovoltaic technology with high efficiency and low manufacturing cost have attracted the attention from ... 相似文献
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