Surface hydrophobization of CNF films by roll-to-roll HMDSO plasma deposition

Cellulosic films are typically sensitive towards moisture which limits their industrial applicability. In this study the films made from cellulose nanofibrils (CNF) were surface silylated with hexamethyldisiloxane (HMDSO) by roll-to-roll plasma deposition. The effects on surface hydrophobicity were clear and indisputable. Water contact angles of non-modified and plasma-deposited CNF films were 23° and 103°, respectively. As a result of surface silylation the relative polarity decreased from 46.8% to 0.6%. Surface hydrophobicity correlated well with the plasma deposition line speeds (0.5, 5, and 10 m/min) and the water vapor barrier properties. Silylation also decreased the oxygen transmission rates both at 50% and 80% relative humidity as compared to non-modified CNF films. All films were completely impermeable to olive oil and intact in contact with castor oil, toluene, and n-heptane or mixtures of them. The developed surface hydrophobization method can be exploited in strengthening the position of cellulosic films in high performance film applications.     

Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody–Drug Conjugation Chemistry

Antibody–drug conjugates (ADCs) are promising alternatives to naked antibodies for selective drug‐delivery applications and treatment of diseases such as cancer. Construction of ADCs relies upon site‐selective, efficient and mild conjugation technologies. The choice of a chemical linker is especially important, as it affects the overall properties of the ADC. We envisioned that hydrophilic bifunctional chemical linkers based on carbohydrates would be a useful class of derivatization agents for the construction of linker–drug conjugates and ADCs. Herein we describe the synthesis of carbohydrate‐based derivatization agents, glycolinker–drug conjugates featuring the tubulin inhibitor monomethyl auristatin E and an ADC based on an anti‐EGFR antibody. In addition, an initial in vitro cytotoxicity evaluation of the individual components and the ADC is provided against EGFR‐positive cancer cells.     

Development and application of an automated subcatchment generator for SWMM using open data

An open source subcatchment generator program was developed for the Stormwater Management Model (SWMM) to automate tedious stages in the model construction process. The generator divides the investigated area into subcatchments using a uniform computation grid and connects the grid cells together and to the underlying stormwater network. The system was tested by applying it to two small urban catchments with different fractions of impervious surfaces in Helsinki, Finland, using mostly openly available data. The simulated discharge results were compared to measured data and to results obtained from manually built models. The proposed system significantly accelerated the setup of a SWMM modelling project, as the routing between the subcatchments as well as the subcatchment slopes and flow widths were directly derived from the computation grid. Automatically generated and manually constructed SWMM models produced discharge results that differed only slightly from each other.     

EOC: Electronic Building Blocks for Embedded Systems

The embedded-object concept, EOC, applies common object-oriented software methods to Lego-like hardware-software entities. These modular entities, representing objects in object-oriented design, function as electronic building blocks that can be assembled into new embedded systems. The goal of the EOC is to make embedded-system design faster and easier while preserving the commercial applicability of the resulting devices.     

Two Methods for Fast Ray‐Cast Ambient Occlusion

Ambient occlusion has proven to be a useful tool for producing realistic images, both in offline rendering and interactive applications. In production rendering, ambient occlusion is typically computed by casting a large number of short shadow rays from each visible point, yielding unparalleled quality but long rendering times. Interactive applications typically use screen‐space approximations which are fast but suffer from systematic errors due to missing information behind the nearest depth layer. In this paper, we present two efficient methods for calculating ambient occlusion so that the results match those produced by a ray tracer. The first method is targeted for rasterization‐based engines, and it leverages the GPU graphics pipeline for finding occlusion relations between scene triangles and the visible points. The second method is a drop‐in replacement for ambient occlusion computation in offline renderers, allowing the querying of ambient occlusion for any point in the scene. Both methods are based on the principle of simultaneously computing the result of all shadow rays for a single receiver point.     

Nonlinear diffusion filtering of images obtained by planar laser-induced fluorescence spectroscopy

The application of nonlinear anisotropic diffusion filtering to reduce noise and enhance contours in images obtained by two-dimensional planar laser-induced fluorescence (PLIF) spectroscopy is presented. In this process the diffusion coefficient is locally adapted, becoming negligible as object boundaries are approached. Noise is efficiently removed, and object contours are strongly enhanced. The technique is demonstrated with PLIF images obtained from the OH radical recorded in turbulent flames. We show that nonlinear diffusion is suitable as a preprocessing step, before image segmentation becomes possible, and we demonstrate how the technique is applied for the quantitative extraction of flame reaction boundaries from PLIF data.     

An overview of CDMA evolution toward wideband CDMA

Third-generation mobile radio networks, often dubbed as 3G, have been under intense research and discussion recently and will emerge around the year 2000. In the International Telecommunications Union (ITU), third generation networks are called International Mobile Telecommunications-2000 (IMT-2000), and in Europe, Universal Mobile Telecommunications System (UMTS). IMT-2000 will provide a multitude of services, especially multimedia and high-bit-rate packet data. Wideband code division multiple access (CDMA) has emerged as the mainstream air interface solution for the third-generation networks. In Europe, Japan, Korea, and the United States, wideband CDMA systems are currently being standarized. This article provides a comprehensive introduction to wideband CDMA. It also provides a review of the wideband CDMA air interface proposals including WCDMA in Europe and Japan, cdma2000 in the United States, and wideband CDMA in Korea.     

Optimizing continuous annealing of interstitial-free steels for improving deep drawability

The crystallographic textures and the resulting plastic anisotropy of five interstitial-free (IF) steels with different carbon equivalents and Nb and Ti microalloying content have been investigated. The steels were industrially hot rolled, cold rolled, annealed, and finally hot-dip galvanized. An alternative heat treatment of the cold rolled samples was conducted in laboratory scale using parameters close to those in industry-scale continuous annealing lines. The anisotropy parameters were both measured and predicted on the basis of the measured texture data. The calculated values were corrected by using functions that were fitted to the experimental data. It was found that for a given hot and cold rolling state even minor changes in the annealing conditions can improve the anisotropy parameter by up to 13 pct. Increase in recrystallization texture and improvement of the resulting anisotropy parameters are discussed in terms of partial transformation of ferrite to austenite in the intercritical regime.     

Direct synthesis of carbon nanofibers on the surface of copper powder

A novel approach to synthesize carbon nanofibers (CNFs) directly on the surface of metal μm-sized particles to evenly disperse the carbon nanomaterials in a composite material was proposed. As a metal matrix, 5–10 μm copper particles were utilized. As a carbon source, C₂H₂, CH₄ and CO were examined. The best conditions were found to be in C₂H₂ (30 cm³/min) and H₂ (260 cm³/min) atmosphere at the temperature of 750 °C. The composites based on copper and CNFs prepared by vacuum hot pressing showed the increase in hardness from 35 to 60 kg/mm² almost retaining pure copper electrical properties.     

Ecological and biological determinants of trace elements accumulation in liver and kidney of Pontoporia blainvillei

The present work tested whether ecological and biological variables have an influence on the assimilation of trace elements by the tissues of a cetacean from the Western South Atlantic Ocean. No significant differences were observed in the concentrations for both sexes. As individuals from the two sampling areas belong to distinct genetic and morphological populations, animals of similar body length were older on the southeastern than on the southern coast. The liver showed the highest concentrations of mercury, whereas the highest levels of cadmium were found in the kidney. Hepatic mercury, cadmium and selenium in individuals from the south coast were about four times as high as those from the southeast coast. However, arsenic in the liver and kidney were similar in both coastal areas. Hepatic mercury, cadmium and selenium concentrations increased with body length in individuals from the southeastern coast, although no significant correlations (P>0.05) were observed between body length from either area and the renal and hepatic As concentrations. A significant positive linear relationship was observed between molar concentrations of Hg and Se in the liver of all individuals from both areas (r2=0.93; P<0.001), presenting Se:Hg ratios close to 4. Differences found among the concentrations of Hg, Cd and Se in dolphins from both areas were probably due to the preferred prey, bioavailability of elements in each marine environment, and environment variables (water temperature, net primary production). As a consequence, concentrations of trace elements in the tissues of this species can be considered to be a result of the surrounding environment.