Myelopathy secondary to ossification of the posterior longitudinal ligament of the thoracic spine treated by anterior decompression and bony fusion

We examined the utility of anterior decompression and bony fusion via the extrapleural approach in the treatment of thoracic myelopathy secondary to ossification of the posterior longitudinal ligament (OPLL). Patient outcome and complications were analyzed in 48 patients treated with this procedure, with a follow-up of at least 2 years. The Japanese Orthopaedic Association score was used to evaluate the severity of the thoracic myelopathy, and the recovery rate was used to evaluate the surgical outcome. The outcome, postoperative complications, radiographic evaluations of bony union, and progression of OPLL within the area of anterior decompression were examined. The T3 vertebral body was the highest level to which anterior decompression was applied. The average follow-up period was 57 months with a recovery rate of 56.7% which stabilized 1 year after operation. However, the surgical outcome was less favorable in patients with long-standing myelopathy, extensive OPLL, or thoracic OPLL with coexisting intraspinal ligament ossification. Four patients experienced deterioration of their myelopathy, and seven patients had the postoperative complication of extraspinal leakage of cerebrospinal fluid. The myelopathy was transient in all but one patient. Radiographic studies showed that bony union was achieved and restenosis of the spinal canal due to progression of OPLL within the area of decompression did not occur. We conclude that anterior decompression and bony fusion using the extrapleural approach provides a good outcome and is useful in treating mid- and lower thoracic OPLL when performed carefully at an early stage of disease.     

A biped walking robot capable of moving on a vertical wall

The use of a wall-climbing robot for purposes such as rescue, wall inspection and fire-fighting on high-rise buildings has been anticipated for a long time. Three different types of wall-climbing robots have been developed in Japan. The first one has a large area sucker, which has the reverse mechanism of a hovercraft. This type can be used only on flat and wide surfaces. The second one has crawlers to move on a vertical wall with many small suckers on them. The third one has a walking mechanism with small suckers on each foot. A biped walking model was built and tested on a vertical wall and a ceiling. The aerodynamic matching between blower performance and required forces of a sucker, as well as the control systems of the robot, are studied in detail.     

Infective endocarditis with a huge mitral vegetation related to atopic dermatitis and high serum level of infection-related antiphospholipid antibody: a case report]

A 24-year-old woman with atopic dermatitis was admitted to our hospital with fever. Echocardiography showed a huge vegetation attached to the posterior mitral commissure without mitral valve dysfunction. Blood culture identified methicillin-sensitive Staphylococcus aureus. The serum level of antiphospholipid antibody was elevated. A splenic infarction occurred on the second hospital day. Surgery to resect the residual mobile vegetation was performed uneventfully on the 6th hospital day. The postoperative course was uneventful, and the patient was discharged after 4 weeks of antibiotic therapy. Preservation of the mitral valve is rare in the face of virulent Staphylococcus infection and the presence of a huge mobile vegetation. These findings were apparently related to the high serum level of infection-related antiphospholipid antibody and atopic dermatitis.     

IL-12 promotes the adhesion of NK cells to endothelial selectins under flow conditions

This study examined the adhesive interactions of peripheral blood NK cells with P- and E-selectin and analyzed the effect of IL-12 on the binding of NK cells to these selectins. P-selectin glycoprotein ligand-1 (PSGL-1) is expressed on most resting and IL-12-activated NK cells. However, the percentage of resting NK cells bound to P-selectin-IgG was 15%, and that of activated NK cells bound to P-selectin-IgG was 65%. Furthermore, the number of IL-12-activated NK cells bound to P-selectin-transfected Chinese hamster ovary cells was significantly higher than that of resting NK cells under flow conditions. These interactions were abolished by the incubation of these NK cells with anti-PSGL-1 (PL-1) mAb. Thus, PSGL-1/P-selectin interaction is important in the binding of resting and activated NK cells to P-selectin. NK cells express sialyl-Lewis(x) (sLe(x)) structure recognized by anti-sLe(x) mAb (KM-93), and IL-12 activation of NK cells increased the mean fluorescence intensity of KM-93-reactive NK cells. Adhesion of IL-12-activated NK cells to E-selectin-transfected Chinese hamster ovary cells was stronger than that of resting NK cells under flow conditions. These interactions were reduced markedly by incubation with anti-sLe(x) mAb. Thus, sLe(x) is the major ligand of resting and activated NK cells for E-selectin. These findings indicate that IL-12 stimulation of NK cells promotes their adhesion activity to endothelial selectins.     

Heat capacities of NpN and AmN

The heat capacities of NpN and AmN were determined with the drop calorimetry method. The NpN and AmN samples were prepared by the carbothermic reduction of the respective dioxides. The heat capacity of NpN obtained was in good agreement with the reported values in the temperature range from 334 to 1067 K, which was close to those of UN and PuN. The heat capacity of AmN was obtained experimentally for the first time, which was slightly smaller than those of UN, NpN and PuN in the temperature range from 354 to 1071 K.     

Relation between dietary behavior and body mass index, serum lipids and socioeconomic factors in urban residents

The purpose of this study was to obtain basic information of factors which improve the dietary behavior of urban residents. For this reason, we studied the relation between dietary behavior and BMI, serum lipids and socioeconomic factors. We surveyed the dietary behavior of those who underwent medical examinations at a health center in the city of A. The subjects for this study were 2,627 persons aged 30 to 69 years. For purposes of analysis, the data derived in the survey was divided into two types of categories. One category is that of practicing and non-practicing group relative to specific dietary behaviors. The other is that of better dietary behaviors group and worse dietary behaviors group. (1) A comparison between the practicing and non-practicing group showed that the mean value of the total cholesterol values for the former was lower than for the latter. Similar results for the triglyceride values was obtained. The mean value of the HDL-cholesterol values for the practicing group was higher than for the non-practicing group. (2) We also compared the better dietary behaviors group with the worse group. For women, the mean value of the body mass indices in the better dietary behaviors group was lower than in worse group. We obtained similar differences for women with regard to the mean values of total cholesterol values and triglyceride values. (3) More of Breslow's health practices were followed by the better dietary behaviors group than by the worse group. (4) The number of good dietary practices was significantly related to the following socioeconomic factors: marital status, floor area of residence, steady employment, and working hours. Better dietary behaviors showed parallel correlation with better health status. Dietary behaviors of younger generations and temporary workers showed a tendency of needing to be improved.     

Prediction of mill load in hot strip mill rolling

It has been ascertained whether or not the model capable of predicting the stress-strain relation of plain carbon steels, previously proposed, is applicable to the estimation of mill loads in the finishing process (consisting of six mill stands) of a hot strip mill. An appreciably good agreement with the predicted and measured mill load values has been obtained in the earlier passes where the strip microstructure is regarded to have completed static recrystallization, and the predicted mill loads in the later passes have been far less than the measured load owing to the effect of the strain accumulated in the previous rolling process. Then, a simple model to predict the accumulated strain has been constructed and introduced into the calculation of mill loads. As a result, the predicted mill loads have been fairly improved over the whole passes in the finishing process.     

Optical-Fiber Feedthrough in Pressure Housing

The structure for introducing fibers into the pressure housing of a submarine optical repeater is studied. As a result of investigations into sealing materials, fiber strength, and optical characteristics, the following structure is adopted. Fibers, whose primary coat is metal instead of silicone, are fixed by epoxy resin to withstand water pressure, and the outside surface of the resin is covered with solder to keep the resin free from water vapor. Experimental results show that this structure meets the requirements.