Glycocalyx‐Like Hydrogel Coatings for Small Diameter Vascular Grafts

Novel biological vascular conduits, such as decellularized tissue engineered vascular grafts (TEVGs) are hindered by high thrombogenicity. To mimic the antithrombogenic surface of native vessels with a continuous glycosaminoglycan layer that is present on endothelial cells (ECs), a hyaluronic acid (HA) modified surface is established, to effectively shield blood platelets from collagen‐triggered activation. Using the amine groups present on 4 mm diameter decellularized TEVGs, a continuous HA hydrogel coating is built via a bifunctional thiol‐reactive cross‐linker, thereby avoiding nonspecific collagen matrix cross‐linking. The HA hydrogel layer recreates a luminal wall, “hiding” exposed collagen from the bloodstream. In vitro blood tests show that adhered platelets, fibrinogen absorption, and fibrin formation on HA‐coated decellularized TEVGs are significantly lower than on uncoated decellularized TEVGs. The HA surface also inhibits macrophage adhesion in vitro. HA‐coated decellularized syngeneic rat aortae (≈1.5 mm diameter), and TEVGs in rat and canine models, respectively, are protected from aggressive thrombus formation, and preserve normal blood flow. Re‐endothelialization is also observed. HA‐coated TEVGs may be an off‐the‐shelf small‐diameter vascular graft with dual benefits: antithrombogenic protection and promotion of endothelium.     

12300 ps/nm, 2.4 Gb/s nonregenerative optical fiber transmissionexperiment and effect of transmitter phase noise

A nonregenerative optical transmission experiment with a chromatic dispersion of more than 10000 ps/nm is reported. Externally intensity-modulated 2.4 Gb/s optical signals were transmitted over 710 km of nondispersion-shifted optical fiber using ten Er-doped fiber amplifiers with a total net optical gain of 125 dB. Although the total chromatic dispersion amounted to 12300 ps/nm, the power penalty observed was as small as 0.5 dB, and an error floor was not observed. The effect of transmitter phase noise associated with fiber chromatic dispersion was experimentally investigated     

Spectral restoration and energy resolution improvement of electron energy-loss spectra by Pixon reconstruction: II. Application to practical ELNES analysis of low SNR

We applied Pixon deconvolution as introduced in Part I to several practical, examples of low signal-to-noise ratio (SNR), electron energy-loss spectra with a goal toward restoring their fine spectral features and/or improving the energy resolution. We demonstrate that by directly fitting the two-dimensional spectral data recorded on the CCD; the method enables us to reveal fine spectral structures. Consequently, Pixon reconstruction extends the ability to probe electronic states in very spatially localized areas, a capability currently unique to our method.     

Statistical analysis on stimulated Raman crosstalk in dispersion-managed fiber links

Power impairments due to stimulated Raman scattering (SRS) in dispersion-managed (DM) fiber links are evaluated theoretically. We extend previous work on the statistical analysis of SRS crosstalk to the case of multiple fiber segments. Closed-form formulas are derived, and the applicable range is presented by comparison with simulation results. The SRS crosstalk in DM fiber links is evaluated using derived formulas, and the preferable configuration of DM fiber links for suppressing SRS crosstalk is discussed. We also evaluate the exact power penalty induced by the SRS crosstalk in consideration of the log-normal waveform distribution due to SRS and non-Gaussian noise and clarify the system bounds in some typical DM fiber links. The developed approach provides a design rule for DM fiber links from the viewpoint of SRS crosstalk suppression.     

Earth‐Abundant and Durable Nanoporous Catalyst for Exhaust‐Gas Conversion

Precious metals (Pt and Pd) and rare earth elements (Ce in the form of CeO₂) are typical materials for heterogeneous exhaust‐gas catalysts in automotive systems. However, their limited resources and high market‐driven prices are principal issues in realizing the path toward a more sustainable society. In this regard, herein, a nanoporous NiCuMnO catalyst, which is both abundant and durable, is synthesized by one‐step free dealloying. The catalyst thus developed exhibits catalytic activity and durability for NO reduction and CO oxidation. Microstructure characterization indicates a distinct structural feature: catalytically active Cu/CuO regions are tangled with a stable nanoporous NiMnO network after activation. The results obtained by in situ transmission electron microscopy during NO reduction clearly capture the unique reaction‐induced self‐transformation of the nanostructure. This finding can possibly pave the way for the design of new catalysts for the conversion of exhaust gas based on the element strategy.     

Evaluation of Stress and Crystal Quality in Si During Shallow Trench Isolation by UV-Raman Spectroscopy

Defects and stress gradually accumulate throughout various Si large-scale integration fabrication processes. It is essential to monitor defects and stress carefully to suppress their unintentional introduction. In this study, we measured the stress and crystal quality in shallow trench isolation (STI) samples by ultraviolet (UV)-Raman spectroscopy with an extremely high-resolution wavenumber to evaluate the effect of post-annealing on the recovery of Si crystals. The variations of crystal quality in 200-mm wafers with STI structures gradually decreased after post-annealing for 4 h, 6 h, and 8 h; however, there was no substantial difference in the values of full-width at half-maximum of the Raman spectra. Precise measurements of variations of stress and crystal quality were successfully performed by UV-Raman spectroscopy with a high-resolution wavenumber, which enabled us to evaluate the STI process accurately.     

CW operation at - 10°C for InGaAlP visible light laser diodes grown by MOCVD

CW operation at - 10°C for InGaP/InGaAlP double heterostructure (DH) laser diodes has been achieved for the first time. The DH wafers were grown by low-pressure metalorganic chemical vapour deposition using methyl metalorganics as the source of group III elements. Under room-temperature pulsed operation, the lasing wavelength was 663 nm and the lowest threshold current density was 7.8 kA/cm2. The CW characteristic temperature T0 was 63 K at around -30°C.     

Heat Transfer & Thermal Stress Analysis of Plastic-Encapsulated ICs

Analytic approaches of thermal stress in plastic-encapslated ICs reliability have been studied using a simple, 2-dimensional model of the cross section of ICs by the finite-element method. To test the validity of the model, the actual stress within the silicon chip was measured using piezoresistive devices. The calculated stress in the silicon chip agreed with the experimental values. The stress distributions were changed by lead-frame properties. Package cracking, and delamination between the molding plastic and the lead-frame were qualitatively explained. We estimated the effect of the plastic properties on stress quantitatively. Furthermore, to test the validity of this model, the temperature change at the silicon chip was measured using the Vf temperature dependency of a diode. The calculated temperature change at the silicon chip agreed with the observed values. A very high temperature gradient was observed near the surface of the plastic immediately after solder dipping. The non-uniform temperature distributions produced different thermal stress distributions than those observed in the steady-state. This result indicated that rapid thermal shock could delaminate the plastic from the lead-frame. We believe that these results can guide the development of an optimum low-stress plastic.     

Oxidation and stress relief in air at room temperature of amorphous silicon hydrogenated in a glow discharge

Glow-discharge-hydrogenated amorphous silicon (a-Si : H) was found to be oxidized in the following two ways after exposing to air at room temperature; first, thin oxide films grew uniformly on the a-Si : H, slowly with increase of exposure time; secondly, oxide with a columnar morphology grew rapidly with the increase of exposure time and the cross section of the columnar oxide was small. Mechanical stress caused by the differences of the thermal expansion coefficient and the crystallographical structure between the a-Si : H and substrates was relieved with the increase in the amount of the columnar oxide.     

Oxygen influence on drawing-induced defect centres and radiation-induced loss in pure silica optical fibres

Drawing-induced defect centres are investigated in pure silica optical fibres drawn from the preforms consolidated in O2-including atmospheres. The drawing-induced E? centres decrease while the peroxy radicals increase with increasing flow rate of O2 into the consolidation furnance. The ?-ray-induced loss of these fibres is also examined.