Technical and Environmental Sustainability Assessment of Water Distribution Systems

An environmental and technical sustainability assessment methodology is developed for both centralized and dual water distribution systems (WDSs) with and without fire flow scenarios. Technical sustainability of potable and reclaimed water networks is measured by a sustainability index (SI) assessment using reliability, resiliency, and vulnerability performance criteria. The U.S. Environmental Protection Agency EPANET software is used to simulate hydraulic (i.e. nodal pressure) and water quality (i.e. water age) analysis in a WDS. Total fresh water use and total energy intensity are considered as environmental sustainability criteria. The procedure considers two separate alternatives for meeting fire flows: (1) adding pumping to a system or (2) adding a non-potable WDS. The reclaimed system is designed using linear programming (LP) optimization. For each alternative, multi-criteria decision analysis (MCDA) is used to combine technical and environmental sustainability criteria for an urban WDS.     

CrimeSPOT: A language and runtime for developing active wireless sensor network applications

Advances in wireless sensing and actuation technology allow embedding significant amounts of application logic inside wireless sensor networks. Such active WSN applications are more autonomous, but are significantly more complex to implement. Event-based middleware lends itself to implementing these applications. It offers developers fine-grained control over how an individual node interacts with the other nodes of the network. However, this control comes at the cost of event handlers which lack composability and violate software engineering principles such as separation of concerns. In this paper, we present CrimeSPOT as a domain-specific language for programming WSN applications on top of event-driven middleware. Its node-centric features enable programming a node’s interactions through declarative rules rather than event handlers. Its network-centric features support reusing code within and among WSN applications. Unique to CrimeSPOT is its support for associating application-specific semantics with events that carry sensor readings. These preclude transposing existing approaches that address the shortcomings of event-based middleware to the domain of wireless sensor networks. We provide a comprehensive overview of the language and the implementation of its accompanying runtime. The latter comprises several extensions to the Rete forward chaining algorithm. We evaluate the expressiveness of the language and the overhead of its runtime using small, but representative active WSN applications.     

A micromechanically motivated finite element approach to the fracture toughness of silicon nitride

Silicon nitride is often used, when high fracture toughness and strength is needed. For a safe and economic structural design with this material, a prediction of its resistance against thermal and mechanical loads is important. The finite element method together with a continuum damage mechanics model allows for such calculations. The parameters of the suggested model have been adjusted to three-dimensional micromechanical finite element simulations, which include models for the microstructure, the thermoelasticity and the fracture. The material model is used for four-point bend test simulations. The results are compared to recent experiments.     

Development of a Cloud Trust Label: A Delphi Approach

The purpose of this research is to identify the potential information components of an online, real-time trust label, which is proposed as a communication mechanism to encourage trust in cloud service providers and cloud computing products. An online Delphi process was used with 28 cloud computing experts (including vendors, software providers, and legal and business representatives). The proposed label contains 81 information components, covering the cloud service provider (e.g. physical location, legal jurisdiction), the cloud service itself (e.g. data location, security, backup, certification), and a historical service-level summary (e.g. uptime data, support response times). The potential benefits of such a label to encourage trustworthiness perceptions and trust behaviors in the cloud computing environment are explored. Limitations of the study are highlighted, and further research studies are suggested to test the concept of the label and to refine the components of the label itself.     

Ramping down a clinical 3 T scanner: a journey into MRI and MRS at 0.75 T

Object

Lower-field MR is reemerging as a viable, potentially cost-effective alternative to high-field MR, thanks to advances in hardware, sequence design, and reconstruction over the past decades. Evaluation of lower field strengths, however, is limited by the availability of lower-field systems on the market and their considerable procurement costs. In this work, we demonstrate a low-cost, temporary alternative to purchasing a dedicated lower-field MR system.

Materials and Methods

By ramping down an existing clinical 3 T MRI system to 0.75 T, proton signals can be acquired using repurposed ¹³C transmit/receive hardware and the multi-nuclei spectrometer interface. We describe the ramp-down procedure and necessary software and hardware changes to the system.

Results

Apart from presenting system characterization results, we show in vivo examples of cardiac cine imaging, abdominal two- and three-point Dixon-type water/fat separation, water/fat-separated MR Fingerprinting, and point-resolved spectroscopy. In addition, the ramp-down approach allows unique comparisons of, e.g., gradient fidelity of the same MR system operated at different field strengths using the same receive chain, gradient coils, and amplifiers.

Discussion

Ramping down an existing MR system may be seen as a viable alternative for lower-field MR research in groups that already own multi-nuclei hardware and can also serve as a testing platform for custom-made multi-nuclei transmit/receive coils.

     

Genetic Deficiency and Pharmacological Stabilization of Mast Cells Ameliorate Pressure Overload-Induced Maladaptive Right Ventricular Remodeling in Mice

Although the response of the right ventricle (RV) to the increased afterload is an important determinant of the patient outcome, very little is known about the underlying mechanisms. Mast cells have been implicated in the pathogenesis of left ventricular maladaptive remodeling and failure. However, the role of mast cells in RV remodeling remains unexplored. We subjected mast cell-deficient WBB6F1-KitW/W-v (Kit^W/Kit^W-v) mice and their mast cell-sufficient littermate controls (MC^+/+) to pulmonary artery banding (PAB). PAB led to RV dilatation, extensive myocardial fibrosis, and RV dysfunction in MC^+/+ mice. In PAB Kit^W/Kit^W-v mice, RV remodeling was characterized by minimal RV chamber dilatation and preserved RV function. We further administered to C57Bl/6J mice either placebo or cromolyn treatment starting from day 1 or 7 days after PAB surgery to test whether mast cells stabilizing drugs can prevent or reverse maladaptive RV remodeling. Both preventive and therapeutic cromolyn applications significantly attenuated RV dilatation and improved RV function. Our study establishes a previously undescribed role of mast cells in pressure overload-induced adverse RV remodeling. Mast cells may thus represent an interesting target for the development of a new therapeutic approach directed specifically at the heart.     

Crack–Tip Toughness of a Soft Lead Zirconate Titanate

Crack–opening displacement (COD) measurements were performed on a commercial lead zirconate titanate (PZT). The intrinsic fracture toughness (or crack–tip toughness) of this material was determined using a new evaluation procedure, which takes into account the near–tip CODs and complete crack profile CODs. The crack–tip toughness K _I0 was determined from an extrapolation of COD data obtained at various loading stages, thus avoiding the complications caused by subcritical crack growth in PZT. Results for plane strain and plane stress condition are presented.