UV reactor flow visualization and mixing quantification using three-dimensional laser-induced fluorescence

Three-dimensional laser-induced fluorescence (3DLIF) was applied to visualize and quantitatively analyze mixing in a lab-scale UV reactor consisting of one lamp sleeve placed perpendicular to flow. The recirculation zone and the von Karman vortex shedding that commonly occur in flows around bluff bodies were successfully visualized. Multiple flow paths were analyzed by injecting the dye at various heights with respect to the lamp sleeve. A major difference in these pathways was the amount of dye that traveled close to the sleeve, i.e., a zone of higher residence time and higher UV exposure. Paths away from the center height had higher velocities and hence minimal influence by the presence of sleeve. Approach length was also characterized in order to increase the probability of microbes entering the region around the UV lamp. The 3DLIF technique developed in this study is expected to provide new insight on UV dose delivery useful for the design and optimization of UV reactors.     

MRPC: A high performance RPC system for MPMD parallel computing

MRPC is an RPC system that is designed and optimized for MPMD parallel computing. Existing systems based on standard RPC incur an unnecessarily high cost when used on high‐performance multi‐computers, limiting the appeal of RPC‐based languages in the parallel computing community. MRPC combines the efficient control and data transfer provided by Active Messages (AM) with a minimal multithreaded runtime system that extends AM with the features required to support MPMD. This approach introduces only the necessary RPC overheads for an MPMD environment. MRPC has been integrated into Compositional C++ (CC++), a parallel extension of C++ that offers an MPMD programming model. Basic performance in MRPC is within a factor of two from those of Split‐C, a highly tuned SPMD language, and other messaging layers. CC++ applications perform within a factor of two to six from comparable Split‐C versions, which represent an order of magnitude improvement over previous CC++ implementations. Copyright © 1999 John Wiley & Sons, Ltd.     

Estimating the Optimal Margins of Embeddings in Euclidean Half Spaces

Concept classes can canonically be represented by matrices with entries 1 and –1. We use the singular value decomposition of this matrix to determine the optimal margins of embeddings of the concept classes of singletons and of half intervals in homogeneous Euclidean half spaces. For these concept classes the singular value decomposition can be used to construct optimal embeddings and also to prove the corresponding best possible upper bounds on the margin. We show that the optimal margin for embedding n singletons is and that the optimal margin for half intervals over {1,...,n} is . For the upper bounds on the margins we generalize a bound by Forster (2001). We also determine the optimal margin of some concept classes defined by circulant matrices up to a small constant factor, and we discuss the concept classes of monomials to point out limitations of our approach.     

Semantic-Web-Technologien in der Arbeitsplatzvermittlung

Zusammenfassung The importance of the Internet for job procurement is increasing for the reason that three quarters of the people in the employment age are online. On the other hand because ever more companies are publishing their job offers on the Web. However, due to the large number of openings published online it is almost impossible for job seekers and job portals to gain an overview of the entire employment market. Since job offers lack semantically meaningful annotations, the search and integration into databases are made highly difficult. Applying Semantic Web technologies to the e-recruitment process provides advantages for all participants in the market. In this paper we describe a method for analysing the domain-specific language of an application domain. We use this method to describe the e-recruitment process and the necessary ontologies for annotating job offers and job applications. In conclusion, we present the prototypical implementation of the scenario based on Semantic Web, especially semantic matching.     

2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo

1. The ability of 2-amino-4-methylpyridine to inhibit the catalytic activity of the inducible NO synthase (NOS II) enzyme was characterized in vitro and in vivo. 2. In vitro, 2-amino-4-methylpyridine inhibited NOS II activity derived from mouse RAW 264.7 cells with an IC50 of 6 nM. Enzyme kinetic studies indicated that inhibition is competitive with respect to arginine. 2-Amino-4-methylpyridine was less potent on human recombinant NOS II (IC50 = 40 nM) and was still less potent on human recombinant NOS I and NOS III (IC50 = 100 nM). NG-monomethyl-L-arginine (L-NMMA), N6-iminoethyl-L-lysine (L-NIL) and aminoguanidine were much weaker inhibitors of murine NOS II than 2-amino-4-methylpyridine but, unlike 2-amino-4-methylpyridine, retained similar activity on human recombinant NOS II. L-NMMA inhibited all three NOS isoforms with similar potency (IC50S 3-7 microM). In contrast, compared to activity on human recombinant NOS III, L-NIL displayed 10 x selectivity for murine NOS II and 11 x selectivity for human recombinant NOS II while aminoguanidine displayed 7.3 x selectivity for murine NOS II and 3.7 x selectivity for human recombinant NOS II. 3. Mouse RAW 264.7 macrophages produced high levels of nitrite when cultured overnight in the presence of lipopolysaccharide (LPS) and interferon-gamma. Addition of 2-amino-4-methylpyridine at the same time as the LPS and IFN-gamma, dose-dependently reduced the levels of nitrite (IC50 = 1.5 microM) without affecting the induction of NOS II protein. Increasing the extracellular concentration of arginine decreased the potency of 2-amino-4-methylpyridine but at concentrations up to 10 microM, 2-amino-4-methylpyridine did not inhibit the uptake of [3H]-arginine into the cell. Addition of 2-amino-4-methylpyridine after the enzyme was induced also dose-dependently inhibited nitrite production. Together, these data suggest that 2-amino-4-methylpyridine reduces cellular production of NO by competitive inhibition of the catalytic activity of NOS II, in agreement with results obtained from in vitro enzyme kinetic studies. 4. When infused i.v. in conscious unrestrained rats, 2-amino-4-methylpyridine inhibited the rise in plasma nitrate produced in response to intraperitoneal injection of LPS (ID50 = 0.009 mg kg-1 min-1). Larger doses of 2-amino-4-methylpyridine were required to raise mean arterial pressure in untreated conscious rats (ED50 = 0.060 mg kg-1 min-1) indicating 6.9 x selectivity for NOS II over NOS III in vivo. Under the same conditions, L-NMMA was nonselective while L-NIL and aminoguanidine displayed 5.2 x and 8.6 x selectivity respectively. All of these compounds caused significant increases in mean arterial pressure at doses above the ID50 for inhibition of NOS II activity in vivo. 5. 2-Amino-4-methylpyridine also inhibited LPS-induced elevation in plasma nitrate after either subcutaneous (ID50 = 0.3 mg kg-1) or oral (ID50 = 20.8 mg kg-1) administration. 6. These data indicate that 2-amino-4-methylpyridine is a potent inhibitor of NOS II activity in vitro and in vivo with a similar degree of isozyme selectivity to that of L-NIL and aminoguanidine in rodents.     

Interaction of a granular stream with an obstacle

We investigate numerically the interaction of a stream of granular particles with a resting obstacle in two dimensions. For the case of high stream velocity we find that the force acting on the obstacle is proportional to the square of the stream velocity, the density and the obstacle size. This behaviour is equivalent to that of non-interacting hard spheres. For low stream velocity a gap between the obstacle and the incoming stream particles appears which is filled with granular gas of high temperature and low density. As soon as the gap appears the force does not depend on the square of velocity of the stream but the dependency obeys another law.     

Test and evaluation of a solar powered gas turbine system

This paper describes the test and the results of a first prototype solar powered gas turbine system, installed during 2002 in the CESA-1 tower facility at Plataforma Solar de Almería (PSA) in Spain. The main goals of the project were to develop a solar receiver cluster able to provide pressurized air of 1000 °C and solve the problems arising from the coupling of the receivers with a conventional gas turbine to demonstrate the operability of the system. The test set-up consists of the heliostat field of the CESA-1 facility providing the concentrated solar power, a pressurized solar receiver cluster of three modules of 400 kWth each which convert the solar power into heat, and a modified helicopter engine (OST3) with a generator coupled to the grid. The first test phase at PSA started in December 2002 with the goal to reach a temperature level of 800 °C at the combustor air inlet by the integration of solar energy. This objective was achieved by the end of this test phase in March 2003, and the system could be operated at 230 kWe power to grid without major problems. In the second test phase from June 2003 to August 2003 the temperature level was increased to almost 1000 °C. The paper describes the system configuration, the component efficiencies and the operation experiences of the first 100 h of solar operation of this very successful first test of a solar operated Brayton gas turbine system.     

The impact of tourism on dune lakes on Fraser Island, Australia

In view of the increasing tourism to Fraser Island, Queensland, a tourist pressure index (TPI) was developed to assess the potential threat of tourism to 15 of the most accessible dune lakes on the island. Tourist pressure index scores indicated that the two clear lakes on the island, Lake McKenzie and Lake Birrabeen, are most threatened by tourist activities owing to their accessibility, facilities and prominence in advertising campaigns. In addition, limnological investigations of the same 15 lakes were conducted in February 1999 to determine their current trophic status and potential susceptibility to adverse impacts from tourism, particularly with reference to eutrophication. On the basis of nutrient and chlorophyll a concentrations, the two water table window lakes, Ocean Lake and Lake Wabby, were classed as mesotrophic and oligo‐mesotrophic, while all of the perched dune lakes were oligotrophic. Lake McKenzie and Lake Birrabeen, the two most threatened lakes according to TPI scores, had the lowest nutrient concentrations of all of the lakes examined and, consequently, we suggest that nutrient additions might elicit rapid algal growth responses in these systems. Comparisons between current data and historical data from Arthington et al. (1990 ) indicate that increases in planktonic chlorophyll a concentrations were not always directly mirrored by increases in total phosphorus concentrations. We found that while chlorophyll a concentrations were significantly higher in the 1999 samples than in the 1990 samples for all lakes, total phosphorus concentrations were higher in Ocean Lake, lower in Lake Jennings and similar in lakes McKenzie, Birrabeen and Wabby.     

Cognitive Processes in Stereotype Formation: The Role of Correct Contingency Learning for Biased Group Judgments.

Three studies investigated contingency learning and stereotype formation in a scenario about group membership and behavior with a confounding context factor. The studies tested predictions from theoretical accounts of biased group judgments in terms of simplistic reasoning, parallel distributed memory, and pseudocontingencies. Study 1 revealed a positive correlation between erroneous stereotype formation and learning of the true contingencies with the confounding factor. Study 2 showed that a focus manipulation during encoding moderated the correlation between stereotype formation and contingency learning but not the strength of the erroneous stereotype. Study 3 used a quasiexperimental comparison between participants with biased versus unbiased group judgments and extended the findings of a positive relation between stereotype formation and contingency learning. The results support an explanation of biased group judgments by pseudocontingencies; that is, unwarranted inferences from accurately perceived bivariate correlations in complex environments. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Experimental and theoretical analysis of relaxation-oscillationsand spectral hole burning effects in all-optical gain-clamped EDFA's forWDM networks

Experimental and theoretical analysis of the gain dynamics of all-optically stabilized multichannel erbium-doped fiber amplifier (EDFA) and the impact on wavelength division multiplexed (WDM) networks performance requirements is presented. In particular, we focus on precise analysis of the detailed transient response of the surviving channel and the relaxation oscillations of the compensating (lasing) signal. The main objective of this work is to experimentally and theoretically analyze and examine some of the critical factors such as, lasing wavelength, gain recovery time, relaxation oscillation frequency of the feedback loop, and the number of channels dropped/added, that affect the transient power excursions in the surviving channel. First, we consider the applicability of laser automatic gain control (AGC) to control fast power transients in WDM optical networks and reports the first high resolution measurements of transients in such gain controlled EDFAs. Second, the experimental results are compared with those predicted from a numerical simulation of the dynamic of the gain controlled EDFA