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171.
Immobilization of whole viable Pseudomonas fluorescens cells was achieved on a graphite electrode modified with a thiophene-based conducting polymer. Microbial electrodes were constructed by the entrapment of bacterial cells on conducting copolymer matrix using a dialysis membrane. The biosensor was characterized using glucose as the substrate. As well as analytical characterization, effects of electropolymerization time, pH and temperature on the sensor response were examined. Finally, operational stability was also tested. 相似文献
172.
Olga Abramova Yana Zorkina Timur Syunyakov Eugene Zubkov Valeria Ushakova Artemiy Silantyev Kristina Soloveva Olga Gurina Alexander Majouga Anna Morozova Vladimir Chekhonin 《International journal of molecular sciences》2021,22(17)
Background: Molecular mechanisms of depression remain unclear. The brain metabolome after antidepressant therapy is poorly understood and had not been performed for different routes of drug administration before the present study. Rats were exposed to chronic ultrasound stress and treated with intranasal and intraperitoneal clomipramine. We then analyzed 28 metabolites in the frontal cortex and hippocampus. Methods: Rats’ behavior was identified in such tests: social interaction, sucrose preference, forced swim, and Morris water maze. Metabolic analysis was performed with liquid chromatography. Results: After ultrasound stress pronounced depressive-like behavior, clomipramine had an equally antidepressant effect after intranasal and intraperitoneal administration on behavior. Ultrasound stress contributed to changes of the metabolomic pathways associated with pathophysiology of depression. Clomipramine affected global metabolome in frontal cortex and hippocampus in a different way that depended on the route of administration. Intranasal route was associated with more significant changes of metabolites composition in the frontal cortex compared to the control and ultrasound groups while the intraperitoneal route corresponded with more profound changes in hippocampal metabolome compared to other groups. Since far metabolic processes in the brain can change in many ways depending on different routes of administration, the antidepressant therapy should also be evaluated from this point of view. 相似文献
173.
The first Born and Rytov approximations of scattering theory are introduced in their less familiar near-field versions. Two algorithms for phase retrieval based on these approximations are then described. It is shown theoretically and by numerical simulations that, despite the differences in their formulation, the two algorithms deliver fairly similar results when used for optical phase retrieval in the near and intermediate fields. The algorithms are applied to derive explicit solutions to four phase-retrieval problems of practical relevance to quantitative phase-contrast imaging and tomography. An example of successful phase reconstruction by use of the Born-type algorithm with an experimental x-ray image is presented. 相似文献
174.
In this study, 4.5 km long fuel pipeline, located on 41° N latitude (Istanbul, Turkey) was cathodically protected with solar energy. Four commercial photovoltaic modules of a 12 V version were used. Insolation data were collected by the aid of Florya Meteorological Station. The cathodic protection was applied for three years and kept under control during this period of time. Project criteria and reliability of the protection have been investigated. Better protection than the available criteria for steel pipeline was achieved even in winter solstice months. 相似文献
175.
Dynamic analysis of a fluidized bed reactor for sucrose inversion catalyzed by immobilized invertase
Axial mixing characteristics and performance of a liquid fluidized bed reactor for the sucrose inversion reaction, which was catalyzed by immobilized invertase was studied. The invertase enzyme was immobilized in polyacrylamide gel by the bead polymerization technique. Well-defined spherical gel particles of five different sizes (0.29–3.16 mm) were prepared. Efficiency of the immobilization technique, the optimum working conditions and the kinetic parameters were determined in a batch system. It is shown that as the particle size increases the rate of inversion first increases due to decrease of enzyme loss by leaching and then decreases because of diffusional limitations after a maixmum is reached. The performance of the fluidized bed reactor was investigated dynamically by introducing a step input of substrate at the inlet and analyzing the response curves. These experiments were performed at the optimum temperature (55°C) and using the optimum particle size (2.15 mm). The axial dispersion coefficient was found to increase from 0.45 to 1.26 cm2/s by changing the liquid velocity from 0.32 to 0.58 cm/s. 相似文献
176.
Gokhan Celik Ayca Arinan Aysegul Bayat H. Onder Ozbelge Timur Dogu Dilek Varisli 《Topics in Catalysis》2013,56(18-20):1764-1774
Dimethyl ether (DME), which is an excellent green diesel fuel alternate, is synthesized following a direct synthesis route from synthesis gas, by using a bi-functional catalyst mixture, which was composed of a silicotungstic acid incorporated mesoporous catalyst [TRC-75(L)] and a commercial Cu–Zn based catalyst. Higher DME selectivity values were obtained by using TRC-75(L), than commercial γ-alumina at 50 bars. Presence of CO2 in the feed stream caused significant enhancement in DME selectivity. Results showed that DME selectivity of about 0.85 was obtained in a temperature range 250–275 °C in the presence of 10 % CO2. In fact, CO2 was also used as a resource to produce DME at lower temperatures. Reverse dry reforming and ethanol formation reactions were observed as side reactions, especially at higher temperatures. Results also proved that direct synthesis of DME from syngas has major CO conversion and DME selectivity advantages over the two step process involving consecutive methanol synthesis and dehydration steps. 相似文献
177.
The management of resources has been claimed to be as important as scheduling methods. Inefficiency in managing resources may bring about severe delays and cost overruns caused by resource shortages in some cases and/or idle resources in others. Therefore, resources should be utilized efficiently to prevent project failures. Resource leveling is one of the approaches that are used for the management of resources. It aims to minimize fluctuations, peaks, and valleys in resource utilization without changing the completion time of a project and the number of resources required. Although the main principle behind traditional resource leveling is achieving an even flow of resources while the original project duration remains unchanged, the literature supports the need to develop an efficient model that discriminates among the activities that are selected for participation in resource leveling. For this purpose, this study has developed a model that considers the float consumption rates of activities in resource leveling. The float consumption rate is the percentage that is set to determine the maximum amount of float which will be consumed to shift the start time of the activity. The proposed model allows a scheduler to assign float consumption rates to each activity that can be used during the resource leveling procedure. When the required information is inputted, the proposed model automatically changes the required daily resources as it shifts the noncritical activities along their available total float times. The proposed model is expected to minimize the likelihood of severe delays and cost overruns. The model is demonstrated by constructing a network and its resource utilization histograms. 相似文献
178.
Igor E. Lyublinski Alexey V. Vertkov Mikhail Yu. Zharkov Vladimir V. Semenov Sergey V. Mirnov Vladimir B. Lazarev Irina L. Tazhibayeva Gennadiy V. Shapovalov Timur V. Kulsartov Alexandr V. D’yachenko Giuseppe Mazzitelli Pietro Agostini 《Fusion Engineering and Design》2013,88(9-10):1862-1865
The projects of ITER and DEMO reactors showed that there are serious difficulties with solving the issues of plasma facing elements (PFE) based on the solid materials. Problems of PFE can be overcome by the use of liquid lithium. Application of lithium will allow to create a self-renewal and MHD stable liquid metal surface of the in-vessel devices possessing practically unlimited service life. Realization of these advantages is based on use of so-called lithium capillary-porous system (CPS) – new material, in which liquid lithium fills a solid matrix from porous material. The progress in development of lithium technology and also lithium experiments in the tokamaks TFTR, T-11M, T-10, FTU, NSTX, LTX, HT-7 and stellarator TJ II is a good basis for development of the project of steady-state operating lithium divertor module for Kazakhstan tokamak. At present the lithium divertor module for KTM tokamak is development and manufacturing. The paper describes main design features of the module of lithium divertor (MLD). The first step of the hydraulic tests of MLD with fully assembled external thermo-stabilization system, which was connected to in-vessel lithium unit, were performed using ethanol as a model heat transfer media. Test results of MLD have shown that operating parameters of designed and manufactured system for thermo-stabilization are sufficient for proper operation; basic hydraulic characteristics of the system are close to expected values. 相似文献
179.
180.
Piao Z Qiu J Wu Y Park SJ He W Timur A Ryu SC Kim HK Hwang YH 《Journal of nanoscience and nanotechnology》2011,11(1):286-290
We studied the effect of nano-tubular anodic TiO2 buffer layers on hydroxyapatite (HA) coating. The pulsed laser deposition (PLD) method was used to deposit HA on a well arranged nano-tubular anodic TiO2 (NT-ATO) buffer layer prepared by an electrochemical anodization technique. The surface morphology and chemical composition of HA coatings were characterized by using scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), and contact angle measurement. We found that crystalline HA coatings show well arranged porous morphologies with a favorable surface wettability. We also found that an anodic nano-tubular TiO2 buffer layer with a relatively short tube length shows a better coating morphology. The deposition process of HA on the nanotubular TiO2 buffer layer was also proposed. 相似文献