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71.
Most of the existing efforts for supporting the design, preparation, and deployment of accessible e-learning applications propose guidelines that primarily address technical accessibility issues. Little, if any, consideration is given to the real actors involved in the learning experience, such as didactical experts and disabled learners. Moreover, implementing artifacts addressed to the e-learning world requires a wide range of particular skills which are related not only to technical but also to didactical, pedagogical, usability, and accessibility aspects of the produced material. This paper argues that the know-how of a number of stakeholders should be blended into a joint design activity, and that it should be possible to determine the role of each participant in the successive phases of the development lifecycle of e-learning applications. The paper sketches the methodological guidelines of a design framework based on involving the users with disabilities, as well as pedagogical experts, in the development process. The novelty of this proposal mainly stems from being built up around the core of strategies and choices specifically bound to accessibility requirements. Characteristic elements of learner-centered design are then further integrated into processes and methodologies which are typical of participatory and contextual design approaches. Following such guidelines, it will be possible to gain a deeper understanding of the requirements and of the operational context of people needing accessible material, either as learners or educators. The underlying objective is to increase the potential to realize learning systems that better meet different user needs and that provide a more satisfying learning experience. Moreover, when people get involved in the development process, they gain a sense of ownership of the system and are therefore more likely to accept and “promote” it.  相似文献   
72.
Random-field model-based algorithms for the detection of anomalous pixels associated with complex valued imagery may be essential to robust focus of attention, target detection, and curing. The described algorithm includes the fitting of a specific class of causal, two-dimensional autoregressive random-field models to image data over specified estimation windows, and then subsequent construction of prediction error samples over specified detection windows. Statistical testing of the calculated prediction error samples is then used to localize anomalous image pixels. Experimental results obtained from running the described algorithm on SAR (synthetic aperture radar) imagery are included.  相似文献   
73.
Microstructural evolution at 1450°C of two 3 mol% Y2O3─ZrO2 tetragonal polycrystals (Y-TZP) containing different residual impurity amounts has been investigated by analytical and scanning electron microscopy in order to clarify the role of the amorphous intergranular phases. Phase partitioning is interpreted as a process based on dissolution/reprecipitation reactions involving mass transport via the liquid impurity phase. Grain growth is inhibited by yttria migration before the phase equilibrium is reached, then increases drastically.  相似文献   
74.
It's hard to deny that robots will become increasingly capable and that humans will increasingly exploit these capabilities by deploying them in ethically sensitive environments, such as hospitals, where ethically incorrect robot behavior could have dire consequences for humans. How can we ensure that such robots will always behave in an ethically correct manner? How can we know ahead of time, via rationales expressed clearly in natural language, that their behavior will be constrained specifically by the ethical codes selected by human overseers? In general, one approach is to insist that robots only perform actions that can be proved ethically permissible in a human-selected deontic logic--that is, a logic that formalizes an ethical code. Ethicists themselves work by rendering ethical theories and dilemmas in declarative form and reasoning over this information using informal and formal logic. The authors describe a logicist methodology in general terms, free of any commitment to particular systems, and show it solving a challenge regarding robot behavior in an intensive care unit.This article is part of a special issue on Machine Ethics.  相似文献   
75.
ETI is an Electronic Tool Integration platform designed for project-oriented, domain-specific, public or private interactive experimentation with heterogeneous tools. Its users can experiment at ease over the web with the integrated tools and functionalities, and build own prototypical problem solvers on the basis of components (tools and transformations) contained in the ETI repository. In this paper we describe the graph concept underlying ETIs flexibility, the significant role played by graphs in the ETI platform, and the kind of support ETI offers to deal with graph objects. This way we sketch the potential of a closer cooperation between the ETI community and the community of research on graph-based tools.  相似文献   
76.
Helicobacter pylori infection is an important cause of peptic ulcer disease and chronic gastritis. Infection with this bacterium stimulates the production of immunoglobulin (Ig) G antibody. Salivary IgG antibody tests to detect H pylori infection offer a convenient and noninvasive method of diagnosis. To evaluate an IgG salivary antibody kit, saliva was collected from 157 out-patients with dyspepsia referred for endoscopy to a tertiary centre. A salivary IgG ELISA antibody assay was performed using the Helisal Helicobacter pylori (IgG) assay kit, and at least four gastric biopsies were obtained. H pylori infection was confirmed by demonstration of the organism on Warthin-Starry silver stain (sensitivity 85%, specificity 55%). The prevalence of infection with H pylori was 30%. When the analysis was redone, excluding those treated with eradication therapy, the results were similar (sensitivity 86%, specificity 58%). The positive predictive value of the assay was 45% and the negative predictive value was 90%. Despite the ease of sampling, the assay used has limited diagnostic utility, lacking the predictive value to indicate which patients referred with dyspeptic symptoms to a tertiary care setting are infected with H pylori.  相似文献   
77.
Patients with end‐stage kidney disease (ESRD) on maintenance hemodialysis (HD) are usually exposed to large volumes of dialysate, which is separated from patients' blood only by thin membrane of dialyzer. It is therefore essential to frequently monitor the quality of HD water to ensure that it meets the recommended standards. The objective of this study was to evaluate the microbial quality of HD water in Lagos, Nigeria. Four sets of pre‐ and post‐treatment water samples, 20 mL each, were collected from six HD centers in Lagos and tested for microbial contamination using the molten Tryptic soy agar in accordance with Association for Advancement of Medical Instrumentation (AAMI) and European Best Practice Guidelines (EBPG). Pyrogen tests were also conducted on pre‐ and post‐treatment samples using standard technique. Information on water treatment modalities, maintenance practices and quality control measures in each center were obtained using a questionnaire. All centers use treated water for HD purpose. None of the HD centers met EBPG/AAMI guidelines for microbial contaminants as the mean levels of Escherichia coli in both feed and treated water were 441.7 ± 87.90 and 168.5 ± 64.03, respectively. E. coli was the commonest organism isolated in both feed and treated water in all the centers. HD water quality is still a neglected problem in our environment and more efforts are required to ensure good water quality for HD purpose.  相似文献   
78.
Life cycle thinking (LCT) is one of the philosophies that has recently appeared in the context of the sustainable development. Some of the already existing tools and methods, as well as some of the recently emerged ones, which seek to understand, interpret and design the life of a product, can be included into the scope of the LCT philosophy. That is the case of the material and energy flow analysis (MEFA), a tool derived from the industrial metabolism definition.This paper proposes a methodology combining MEFA with another technique derived from sustainable development which also fits the LCT philosophy, the BAT (best available techniques) analysis. This methodology, applied to an industrial process, seeks to identify the so-called improvable flows by MEFA, so that the appropriate candidate BAT can be selected by BAT analysis. Material and energy inputs, outputs and internal flows are quantified, and sustainable solutions are provided on the basis of industrial metabolism.The methodology has been applied to an exemplary roof tile manufacture plant for validation. 14 Improvable flows have been identified and 7 candidate BAT have been proposed aiming to reduce these flows.The proposed methodology provides a way to detect improvable material or energy flows in a process and selects the most sustainable options to enhance them. Solutions are proposed for the detected improvable flows, taking into account their effectiveness on improving such flows.  相似文献   
79.
Abstract: This paper proposes a method to enzymatically treat poor‐quality cocoa almonds (known as “slate”) to ensure the formation of chocolate flavor precursors. The production of flavor precursors improves the quality of these almonds, which are usually responsible for the low quality of the liquor produced. Proteases and carboxypeptidases from different sources were tested under various conditions. The different treatments were evaluated by chemical analysis (hydrolysis efficiency) and sensory analysis of the treated material compared to good‐quality cocoa almonds. The results show that it is possible, through the use of microbial enzymes, to generate the mixture of compounds that will release, after roasting, the characteristic chocolate flavor in poor‐quality almonds. However, it is necessary to optimize the conditions of enzymatic treatment to obtain better results and thus establish a process that can be used for industrial purposes for manufacturing cocoa and chocolate. Practical Application: The basidiomycete Moniliophtora perniciosa is the causative agent of witches’ broom disease (WBD) of the cocoa tree, whose seeds are the source of chocolate. It is the most important phytopathological problem of cocoa‐producing areas of the American continent, and has decimated the Brazilian cocoa industry. In Bahia (Brazil), M. perniciosa was identified in 1989 and, as a consequence of its spreading, the annual production of cocoa almonds dropped from 450000 to 90000 tons within 12 y, reducing export values from an all‐time high of about US$ 1 billion to 110 million. The high incidence of WBD incapacitates Brazil to produce enough cocoa almonds even for the internal market, leading the country to import low‐quality cocoa almonds mainly from African countries. Our work proposes an enzymatic treatment to increase the quality of that cocoa almonds and, consequently, to improve the quality of the chocolate produced and consumed in the country.  相似文献   
80.
The use of mobile sensors is of great relevance to monitor critical areas where sensors cannot be deployed manually. The presence of data collector sinks causes increased energy depletion in their proximity, due to the higher relay load under multi-hop communication schemes (sink-hole phenomenon). We propose a new approach towards the solution of this problem by means of an autonomous deployment algorithm that guarantees the adaptation of the sensor density to the sink proximity and enables their selective activation. The proposed algorithm also permits a fault tolerant and self-healing deployment, and allows the realization of an integrated solution for deployment, dynamic relocation and selective sensor activation. We formally prove the termination of our algorithm. Performance comparisons between our proposal and previous approaches show how the former can efficiently reach a deployment at the desired variable density with moderate energy consumption under a wide range of operative settings.  相似文献   
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