c-KIT expression enhances the leukemogenic potential of 32D cells

The growth of human leukemic cells in culture and in vivo is dependent upon the presence of hematopoietic growth factors. Most populations of human leukemic acute myeloblastic leukemia (AML) cells express c-Kit on their surface and respond to Kit ligand (KL) in culture. To determine if this interaction was of potential significance in vivo we used a mouse model system. 32D cells, a murine IL-3-dependent myeloid cell line, were rendered KL responsive by transfection of the murine c-Kit. After injection of 32D or 32D-Kit cells into syngeneic hosts, animals bearing 32D-Kit cells, but not 32D cells, became moribund and were killed. These animals had circulating leukemic blast cells, infiltration of bone marrow, spleen, brain, liver, lung, and kidney. Cells recovered from some of the animals continued to be dependent upon IL-3 or KL for growth while in other cases the cells were factor independent. This model illustrates that the constitutive expression of c-Kit enhances the leukemic potential of 32D cells. The model will be useful for studying the progression of leukemia in vivo and testing whether interruption of the interaction of Kit and KL can affect the growth of leukemic cells.     

Performance analysis of the bidirectional associative memory and animproved model from the matched-filtering viewpoint

This paper discusses the bidirectional associative memory (BAM) model from the matched-filtering viewpoint and offers it a new interpretation. Our attention is focused on the problem of stability and attractivity of equilibrium states. Several sufficient and/or necessary conditions are presented. To improve the BAM performance, an exponential function is used to enhance the correlations between the binary vectors of the retrieval key and that of the stored pattern similar to the key. The modified model is shown to be asymptotically stable. Theoretical analysis and simulation results demonstrate that the modified model performs much better than the original BAM in terms of memory capacity and error correction capability.     

The Silicon Backplane Design for an LCOS Polarization-Insensitive Phase Hologram SLM

Polarization-insensitivity is achieved in a reflective spatial light modulator by laying a quarter-wave plate (QWP) at the incident wavelength directly over the mirror pixels of a silicon backplane, and forming a nematic Freedrickcz cell over the QWP to modulate the reflected phase. To achieve the highest drive voltage from the available silicon process, a switched voltage common front electrode design is described, with variable amplitude square wave drive to the pixels to maintain constant root-mean-square drive and minimize phase fluctuations during the dc balance refresh cycle. The silicon has been fabricated and liquid-crystal-on-silicon cells both with and without the QWP assembled; applications include optically transparent switches for optical networks, beam steering for add-drop multiplexers for wavelength-division-multiplexing telecommunications, television multicast, and holographic projection.     

Novel algorithms for shared segment protection

The major challenges in designing survivable schemes are how to allocate a minimal amount of spare resources (e.g., bandwidth) using fast (e.g., polynomial-time) algorithms, and, in case a failure occurs, to be able to recover quickly from it. All existing approaches invariably make tradeoffs. We propose novel shared segment protection algorithms which make little or no compromise . We develop an elegant integer linear programming (ILP) model to determine an optimal set of segments to protect a given active path. Although the ILP approach is useful for a medium-size network, it is too time consuming for large networks. Accordingly, we also design a fast heuristic algorithm based on dynamic programming to obtain a near-optimal set of segments. Although the heuristic algorithm has a polynomial time complexity, it can achieve a bandwidth efficiency as high as some best-performing shared path protection schemes and, at the same time, much faster recovery than these shared path protection schemes. The proposed scheme is also applicable to a wide range of networking technologies, including Internet Protocol and wavelength-division multiplexing networks under the generalized multiprotocol label switched framework.     

Occlusion-resistant camera design for acquiring active environments.

In this article, we present a detailed theoretical analysis and a prototype implementation of a family of cameras designed with the explicit goal of detecting and removing interfering dynamic occluders in real time, during live capture, as opposed to fixing the resulting artifacts a posteriori. Such an early-acquisition approach improves efficiency: more valid samples are acquired faster without worrying about moving occluders. One option for designing a camera to be unaffected by moving occluders is to sample through the occluder, but true x-ray-like vision is technically impractical. Another option is to sample around the occluder using a camera with a large effective aperture, but such an approach requires a bulky acquisition device. Yet another possibility of sampling around an occluder is to rely on second and higher order reflected rays that indirectly sample surfaces not directly visible. However, devising an acquisition device sufficiently sensitive and efficient to capture large environments using reflected rays will remain challenging for the foreseeable future.     

An improved covariance assignment theory for discrete systems

For discrete systems, the set of all state covariances X which can be assigned to the closed-loop system via a dynamic controller is characterized explicitly. For any assignable state covariance X , the set of all controllers that assign this X to the closed-loop system is parameterized with an arbitrary orthonormal matrix U of proper dimension     

川东地区长兴组缝洞型储层的识别

本文针对四川东部地区上二叠统长兴组(P_2~2)缝洞型储层的低孔、低渗及非均质性等特点,分析了影响这类储层识别的主要因素,提出了利用现有的地球物理测井手段定性识别储层的指标和定量综合识别储层的方法,这可望提高测试成功率。