全文获取类型
收费全文 | 275篇 |
免费 | 10篇 |
专业分类
电工技术 | 27篇 |
化学工业 | 65篇 |
金属工艺 | 7篇 |
机械仪表 | 5篇 |
建筑科学 | 10篇 |
矿业工程 | 2篇 |
能源动力 | 9篇 |
轻工业 | 22篇 |
无线电 | 9篇 |
一般工业技术 | 44篇 |
冶金工业 | 53篇 |
原子能技术 | 3篇 |
自动化技术 | 29篇 |
出版年
2023年 | 1篇 |
2022年 | 8篇 |
2021年 | 8篇 |
2020年 | 4篇 |
2019年 | 6篇 |
2018年 | 4篇 |
2017年 | 5篇 |
2016年 | 11篇 |
2015年 | 8篇 |
2014年 | 7篇 |
2013年 | 13篇 |
2012年 | 11篇 |
2011年 | 11篇 |
2010年 | 4篇 |
2009年 | 11篇 |
2008年 | 11篇 |
2007年 | 17篇 |
2006年 | 13篇 |
2005年 | 7篇 |
2004年 | 12篇 |
2003年 | 8篇 |
2002年 | 8篇 |
2001年 | 4篇 |
2000年 | 1篇 |
1999年 | 5篇 |
1998年 | 23篇 |
1997年 | 10篇 |
1996年 | 9篇 |
1995年 | 4篇 |
1994年 | 4篇 |
1993年 | 6篇 |
1992年 | 4篇 |
1991年 | 2篇 |
1990年 | 2篇 |
1989年 | 4篇 |
1988年 | 4篇 |
1987年 | 1篇 |
1986年 | 3篇 |
1985年 | 3篇 |
1984年 | 2篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1977年 | 1篇 |
1976年 | 2篇 |
1975年 | 1篇 |
排序方式: 共有285条查询结果,搜索用时 15 毫秒
71.
Atsushi Sano Tsuneo SatohTetsuya Oguma Akinori NakatohJun-ichi Satoh Toshifumi Ohgawara 《Food chemistry》2007,105(3):1242-1247
A novel method using liquid chromatography coupled with mass spectrometry (LC–MS) was developed for the determination of levulinic acid (LV) in soy sauces to identify the addition of acid hydrolyzed vegetable protein (acid-HVP). One hundred percentage naturally brewed soy sauce (NBS) and enzymatic hydrolyzed vegetable protein (enzymatic HVP) did not contain LV (<0.01 mg/mL). There was apparent detection of LV in acid-HVP and blended soy sauce with acid-HVP (2.98–21.66 mg/mL). Gas chromatography (GC) and high performance liquid chromatography (HPLC) at 430 nm methods were also investigated. The results by GC gave similar data to those by LC–MS. In enzymatic HVP, LV was detected by HPLC at 430 nm, but it was confirmed that the detected component was not in fact LV by mass spectrometric identification of the isolated peak compound. We found that LV is under the detection limit in enzymatic HVP. This study showed that LV is below the detection limit in NBS and enzymatic HVP and is apparently detected in acid-HVP and blended soy sauces with acid-HVP. These results indicate that LV is a practical index of blend with acid-HVP and also corresponds with the JAS (Japanese Agricultural Standard) or CNS (Chinese National Standard) criteria in which the presence of LV in soy sauces indicates adulteration with acid-HVP. The LC–MS method is analytically optimal for the precise determination of LV, because peak misidentification may be practically eliminated. 相似文献
72.
73.
74.
The thermoluminescence glow-curve of quartz in volcanic and pyroclastic rocks of the Miocene and Quaternary in the Kakkonda geothermal field was divided into L (low), M (medium) and H (high) peaks in order of increasing temperature. Thermoluminescence emission is independent of stratigraphic boundaries but it is closely related to surface geothermal manifestations. Thermally stimulated processes of thermoluminescence caused by natural annealing occurred in the Quaternary after the eruption of the Tamagawa Welded Tuffs; radiation storage processes then began, as a consequence of the temperature drop. Thermoluminescence behavior indicates natural temperature manifestations, together with the paleo-temperature history.The H peak was thermally stable compared to the L and M peaks, and the area within which the relative intensity of the H peak is less than 5% coincides with the surface zone where dominant fluid flow is convective. In addition, L and M peaks indicate that a relatively low-temperature fluid mixes with the hot upflow around the western margin of the ascending flow zone.Thermoluminescence characteristics reflect paleo-temperature history and are related to geothermal fluid flow. Thermoluminescence is an effective exploration technique for evaluating natural temperature manifestations and subterranean heat flow in geothermal systems. 相似文献
75.
Toshifumi Mukunoki Daisuke Suetsugu Kazunari Sako Satoshi Murakami Yoshinori Fukubayashi Ryohei Ishikura Takenori Hino Satoshi Sugimoto Kota Wakinaka Shinichi Ito Atsushi Koyama 《Soils and Foundations》2021,61(2):600-620
Kumamoto and Kogoshima prefectures are located in the southern Kyushu district of western Japan. In July 2020, a warm, humid air front triggered the delayed rains of the rainy season, resulting in torrential rains in many parts of Japan, especially in Kyushu. In particular, heavy downpours occurred in the southern Kyushu district on July 4th, causing severe damage to much of the infrastructure. Details could not be analyzed as usual because some branch office of local government were also damaged by floods. The spatial distribution of precipitation in the Kuma River basin, in the southern part of Kumamoto, was characterized by the uniformity of 400–500 mm on July 3rd and 4th. Finally, emergency warnings of torrential rain were issued for the southern Kumamoto and the northern Kagoshima Prefectures by Japan Meteorological Agency (JMA) at 4:50 a.m., July 4th, 2020. Then, the active rain front gradually shifted towards northern Kyushu. Again, torrential rain fell on northern Kyushu in the afternoon due to a stagnant rainy season front, and the JMA issued an emergency warning for a localized torrential downpour for parts of Fukuoka, Saga and Nagasaki prefectures at 4:30 pm. Gradually, the damage status involving geodisasters such as several types of slope failures, road subsidence, damage of the river levee was reported by local governments in each area where there had been emergency warnings.Based on the brief report of the pre-investigation team from the Kyushu branch of the Japan Geotechnical Society (JGS) in the first week after the disaster on July 4th, the geo-research teams investigated the following: 1) landslides; 2) damaged roads; 3) damaged river levees, and 4) any geotechnical infrastructures which were partially damaged and may be even more severely damaged by the next torrential rain. This reconnaissance report introduces the geological features in Kyushu, the analysis of precipitation distribution and geotechnical damages on the slope failures, road failures and river embankments based on reports obtained from July 4th to August 31st, 2020. 相似文献
76.
Masahiro Koyama Yasushi Ogasawara Kiyoshi Endou Hirofumi Akano Takero Nakajima Toshifumi Aoyama 《International Journal of Food Properties》2017,20(4):888-898
Various raw materials are used to produce vinegars that contain functional compounds associated with disease prevention. We evaluated changes in functional compounds during tomato vinegar production and superoxide dismutase-like activity of tomato vinegar. Tomato vinegar contained abundant anti-hypertensive compounds, e.g., γ-aminobutyric acid and potassium derived from tomatoes and acetic acid and pyroglutamic acid produced during fermentation. It had stronger superoxide dismutase-like activity than commercial vinegars because of tomato-derived superoxide dismutase-like compounds, including phenolic acids, flavonoids, and glutathione. These data indicate that tomato vinegar is a candidate dietary supplement with potential preventive effects against cardiovascular diseases due to its anti-hypertensive and superoxide dismutase-like compounds. 相似文献
77.
Nakagawa T Kurita N Kozakai S Iwabuchi S Yamaguchi Y Hayakawa M Ito Y Aoyama T Nakajima T 《Journal of molecular graphics & modelling》2008,27(1):45-58
Peroxisome proliferator-activated receptor α (PPARα) has various physiological functions such as lipid and glucose metabolism, inflammation and fibrosis in living organisms. Many types of ligand molecules such as phthalate and adipate esters control these physiological functions. In the present study, to elucidate the dependence of PPARα properties on ligand binding, we investigated stable structures and electronic properties for the complexes of PPARα and phthalate as well as adipate esters, which are used as a plasticizer, by molecular simulations based on molecular mechanics and molecular orbital methods. Furthermore, to elucidate the influence of these esters in vivo, we injected them into male mice and observed the change in the expression of PPARα-related enzymes. The comparison between the calculated and observed results indicates that the change in the expression has a correlation with the size of energy gaps between highest occupied and lowest unoccupied molecular orbitals of the complexes with mouse PPARα and esters. 相似文献
78.
Mayuko Ikarashi Junko Tsuchida Masayuki Nagahashi Shiho Takeuchi Kazuki Moro Chie Toshikawa Shun Abe Hiroshi Ichikawa Yoshifumi Shimada Jun Sakata Yu Koyama Nobuaki Sato Nitai C. Hait Yiwei Ling Shujiro Okuda Kazuaki Takabe Toshifumi Wakai 《International journal of molecular sciences》2021,22(24)
Although numerous experiments revealed an essential role of a lipid mediator, sphingosine-1-phosphate (S1P), in breast cancer (BC) progression, the clinical significance of S1P remains unclear due to the difficulty of measuring lipids in patients. The aim of this study was to determine the plasma concentration of S1P in estrogen receptor (ER)-positive BC patients, as well as to investigate its clinical significance. We further explored the possibility of a treatment strategy targeting S1P in ER-positive BC patients by examining the effect of FTY720, a functional antagonist of S1P receptors, on hormone therapy-resistant cells. Plasma S1P levels were significantly higher in patients negative for progesterone receptor (PgR) expression than in those positive for expression (p = 0.003). Plasma S1P levels were also significantly higher in patients with larger tumor size (p = 0.012), lymph node metastasis (p = 0.014), and advanced cancer stage (p = 0.003), suggesting that higher levels of plasma S1P are associated with cancer progression. FTY720 suppressed the viability of not only wildtype MCF-7 cells, but also hormone therapy-resistant MCF-7 cells. Targeting S1P signaling in ER-positive BC appears to be a possible new treatment strategy, even for hormone therapy-resistant patients. 相似文献
79.
Kenji Rowel Q. Lim Md Nur Ahad Shah Stanley Woo Harry Wilton-Clark Pavel Zhabyeyev Faqi Wang Rika Maruyama Gavin Y. Oudit Toshifumi Yokota 《International journal of molecular sciences》2021,22(23)
Dystrophin is a 427 kDa protein that stabilizes muscle cell membranes through interactions with the cytoskeleton and various membrane-associated proteins. Loss of dystrophin as in Duchenne muscular dystrophy (DMD) causes progressive skeletal muscle weakness and cardiac dysfunction. Multiple promoters along the dystrophin gene (DMD) give rise to a number of shorter isoforms. Of interest is Dp71, a 71 kDa isoform implicated in DMD pathology by various animal and patient studies. Strong evidence supporting such a role for Dp71, however, is lacking. Here, we use del52;WT mice to understand how Dp71 overexpression affects skeletal and cardiac muscle phenotypes. Apart from the mouse Dmd gene, del52;WT mice are heterozygous for a full-length, exon 52-deleted human DMD transgene expected to only permit Dp71 expression in muscle. Thus, del52;WT mice overexpress Dp71 through both the human and murine dystrophin genes. We observed elevated Dp71 protein in del52;WT mice, significantly higher than wild-type in the heart but not the tibialis anterior. Moreover, del52;WT mice had generally normal skeletal muscle but impaired cardiac function, exhibiting significant systolic dysfunction as early as 3 months. No histological abnormalities were found in the tibialis anterior and heart. Our results suggest that Dp71 overexpression may have more detrimental effects on the heart than on skeletal muscles, providing insight into the role of Dp71 in DMD pathogenesis. 相似文献
80.
Hiroshi Nagashima Toshifumi Ishikura Mitsuharu Ide 《Korean Journal of Chemical Engineering》1999,16(5):688-693
A spouted bed with an impermeable draft tube was employed to obtain fundamental data of binary mixtures of glass beads for
both the operating conditions and the design factors. These data were compared with those for the coarser particle system
only. From this view point, minimum spouting velocity, pressure drop, hold-up of solid particles within a draft tube, upward
gas flow rate within the annulus and solids circulation rate were determined by changing the total gas flow rate and mass
fraction of finer particles as operating parameters and by changing distance of entrainment zone and draft tube diameter as
geometric parameters. 相似文献