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51.
Presented is a register structure and generator design which enables non-scan sequential testing using parallel pseudorandom-based patterns applied to the circuit's primary inputs. The proposed register structure and register control strategy uses the circuit under test's (CUT's) natural sequential activity to periodically alter a register's output bias to a value near 0.5 (i.e. alter the spread of 1's in the output stream). Thus, over time, it is possible to introduce a larger spread circuit states than that normally reachable when parallel pseudorandom-based test patterns are applied to the input lines of a CUT. Using the register modification, a simple hardware generation system can be designed and is suitable for both on-chip and external testing. Experiments indicate that high fault coverage is attainable in a relatively short test time. 相似文献
52.
Katsuhisa Tanaka Takash Mukai Tsuguo Ishihara Kazuyuki Hirao Naohiro Soga Seiji Sogo Masaaki Ashida Riso Kato 《Journal of the American Ceramic Society》1993,76(11):2839-2845
Transparent glass-ceramics containing ZnAl2 O4 :Co2+ and LiGa5 O8 :Co2+ crystallites have been prepared by heat treatment of glasses in the zinc aluminosilicate and lithium gallate silicate systems, respectively. Crystalline LiGa5 O8 was already precipitated in an as-prepared specimen, while ZnAl2 O4 :Co2+ precipitated from the glass upon heat treatment. The crystallite size varies from about 5 to 20 nm with increasing heat treatment temperature for both systems, and glass-ceramics containing crystallites of less than about 10 nm are transparent. The low-temperature optical absorption and emission spectra are compared with those of single crystals, indicating that almost all of the Co2+ ions replace Zn2+ ions in the ZnAl2 O4 system, while some of the Co2+ ions are incorporated into the LiGa3 O8 system, although the amount of Co2+ which remains in the glass matrix is rather large in the latter system. 相似文献
53.
54.
Design and Synthesis of A‐Ring Simplified Pyripyropene A Analogues as Potent and Selective Synthetic SOAT2 Inhibitors
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Dr. Masaki Ohtawa Shiho Arima Naoki Ichida Tomiaki Terayama Hironao Ohno Takaya Yamazaki Dr. Taichi Ohshiro Noriko Sato Prof. Satoshi Omura Prof. Hiroshi Tomoda Prof. Tohru Nagamitsu 《ChemMedChem》2018,13(5):411-421
Currently, pyripyropene A, which is isolated from the culture broth of Aspergillus fumigatus FO‐1289, is the only compound known to strongly and selectively inhibit the isozyme sterol O‐acyltransferase 2 (SOAT2). To aid in the development of new cholesterol‐lowering or anti‐atherosclerotic agents, new A‐ring simplified pyripyropene A analogues have been designed and synthesized based on total synthesis, and the results of structure–activity relationship studies of pyripyropene A. Among the analogues, two A‐ring simplified pyripyropene A analogues exhibited equally efficient SOAT2 inhibitory activity to that of natural pyripyropene A. These new analogues are the most potent and selective SOAT2 inhibitors to be used as synthetic compounds and attractive seed compounds for the development of drug for dyslipidemia, including atherosclerotic disease and steatosis. 相似文献
55.
Front Cover: Design and Synthesis of A‐Ring Simplified Pyripyropene A Analogues as Potent and Selective Synthetic SOAT2 Inhibitors (ChemMedChem 5/2018)
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56.
Atsushi Taguchi Takashi Miyoshi Yasuhiro Takaya Satoru Takahashi 《Precision Engineering》2004,28(2):7253
We have proposed an optical method that can be applied to in-process or in situ measurement of the microsurface profile. The present method is based on optically performed spectral analysis and the phase retrieval technique. Spectral information of a surface profile is obtained by measuring the Fraunhofer diffraction intensity. The phase retrieval technique is used to reconstruct the surface profile from the measured spectrum. We have developed an instrument on the basis of the general principles of the present method, and measured the surface of a reference standard having rectangular pockets 44 nm deep at intervals of 10 μm. The measured surface profile was in good agreement with the nominal dimensions of the specimen as well as the surface profile obtained by atomic force microscopy (AFM). 相似文献
57.
Yasunari Ishikawa Seiji Kuroda Jin Kawakita Matsufumi Takaya 《Surface & coatings technology》2007,201(8):4718-4727
WC-20 mass%Cr3C2-7 mass%Ni powder was sprayed onto low-carbon steel substrates by a commercial high velocity oxygen-fuel (HVOF) spray process as well as by an improved HVOF process equipped with a gas shroud attachment. The latter process utilizes a nitrogen gas flow to shield the region between the spray gun and the substrate in order to suppress the material's degradation caused by reaction with air such as oxidation and decarburization. Some coatings were further heat-treated in air at 773 K for 30 h to form a thin oxide film on the surface. The sliding wear properties of these coatings against an iron pin were evaluated by using a pin-on-disk wear tester. The specific wear rate of the as-sprayed cermet coatings prepared under the conventional spray condition was about three times higher than that of the chrome plating but by using the gas shroud, the wear rate was reduced to the same level with the chrome plating. The specific wear rate could be further decreased by the oxidation heat-treatment. It was found that a proper amount of oxides existing on the surface or within the coatings have a great beneficial effects on the wear properties such as to promote the transition from severe wear to mild wear and thus to reduce the wear rate remarkably. XPS analysis of the transfer particles collected from the wear track revealed a shift in the oxidation state of iron depending on the wear condition. 相似文献
58.
Takaya Arita Michał Joachimczak Takashi Ito Atsushi Asakura Reiji Suzuki 《Artificial Life and Robotics》2016,21(2):141-148
Evolutionary developmental biology, evo-devo, emerged to integrate evolution and development in the 1980s, in which evolution is conceptualized as heritable changes in development. Recently, the field is moving to a new synthesis: ecological evolutionary developmental biology, eco-evo-devo. We believe that artificial life (ALife) approach will provide new insights into the field, and also contribute to the field of robotics through the emergence perspective and the constructive methodology. This paper explores the potential of such an artificial life approach based on the evolution of virtual creatures by presenting our ongoing studies with three models: (1) metamorphosis model, (2) exaptation model and (3) Prey-predator model. 相似文献
59.
Tadayoshi Matsumori Atsushi Kawamoto Tsuguo Kondoh Tsuyoshi Nomura Hidetaka Saomoto 《Structural and Multidisciplinary Optimization》2017,56(3):619-629
This paper deals with a design method for boundary shapes using filtering techniques based on a partial differential equation (PDE). In shape optimization, it is known that oscillatory boundaries appear when design variables are directly assigned to the design boundaries. In addition, during the optimization process, discretized elements in a computational domain are distorted due to extremely large shape changes along the design boundaries. The distorted elements may cause accuracy deterioration or numerical instability in a forward problem. In this paper, we propose a shape optimization method by using the PDE as a low pass filter which prevents the oscillatory boundaries of the optimized design. For restricting the shape distortion of the discretized elements, the shear deformation of the elements is constrained in the optimization problem. Mathematical programming is used to find the boundary shapes under the KKT conditions. The effectiveness of the proposed method is demonstrated through numerical examples in solid and fluid mechanics. 相似文献
60.
Yomi?Watanabe Yoshie?Yamauchi-Sato Toshihiro?Nagao Takaya?Yamamoto Kentaro?Tsutsumi Akio?Sugihara Yuji?ShimadaEmail author 《Journal of the American Oil Chemists' Society》2003,80(9):909-914
We attempted to produce MAG of CLA through lipase-catalyzed esterification of a FFA mixture containing CLA (referred to as
FFA-CLA) with glycerol. Screening of lipases showed that MAG-CLA was produced efficiently at 5°C with Penicillium camembertii, Rhizopus oryzae, and Candida rugosa lipases. Among them, C. rugosa lipase was selected because the lipase is widely used as a catalyst for oils and fats processing. The reaction was conducted
with agitation of a 300-g mixture of FFA-CLA/glycerol (1∶5, mol/mol), a 200-U/g mixture of C. rugosa lipase, and 2% water. When the reaction was conducted at 30°C, the esterification scarcely proceeded, owing to inhibition
of the reaction by glycerol. But the reaction at 5°C eliminated the inhibition and produced MAG efficiently: The degree of
esterification reached 93.8% after 58 h, and MAG content in the reaction mixture was 88.4 wt%. To reduce the reaction time,
the reactor was connected with a vacuum pump after 24 h, and the reaction was continued with dehydration at 5 mm Hg. The degree
of esterification reached 94.7% after 24 h of dehydration (48 h in total), and MAG content increased to 93.0 wt%. Candida rugosa lipase acted a little more strongly on cis-9, trans-11 CLA than on trans-10,cis-12 CLA, but the contents of the two isomers in MAG obtained from a 48-h reaction were the same as the contents in FFA-CLA. 相似文献