全文获取类型
收费全文 | 2020篇 |
免费 | 65篇 |
专业分类
电工技术 | 24篇 |
化学工业 | 288篇 |
金属工艺 | 39篇 |
机械仪表 | 30篇 |
建筑科学 | 68篇 |
矿业工程 | 16篇 |
能源动力 | 36篇 |
轻工业 | 233篇 |
水利工程 | 19篇 |
石油天然气 | 5篇 |
无线电 | 136篇 |
一般工业技术 | 297篇 |
冶金工业 | 631篇 |
原子能技术 | 29篇 |
自动化技术 | 234篇 |
出版年
2023年 | 12篇 |
2022年 | 21篇 |
2021年 | 40篇 |
2020年 | 35篇 |
2019年 | 35篇 |
2018年 | 36篇 |
2017年 | 40篇 |
2016年 | 49篇 |
2015年 | 26篇 |
2014年 | 35篇 |
2013年 | 77篇 |
2012年 | 54篇 |
2011年 | 101篇 |
2010年 | 72篇 |
2009年 | 60篇 |
2008年 | 60篇 |
2007年 | 64篇 |
2006年 | 68篇 |
2005年 | 54篇 |
2004年 | 45篇 |
2003年 | 42篇 |
2002年 | 41篇 |
2001年 | 32篇 |
2000年 | 20篇 |
1999年 | 40篇 |
1998年 | 155篇 |
1997年 | 99篇 |
1996年 | 73篇 |
1995年 | 48篇 |
1994年 | 49篇 |
1993年 | 37篇 |
1992年 | 25篇 |
1991年 | 21篇 |
1990年 | 21篇 |
1988年 | 16篇 |
1987年 | 13篇 |
1986年 | 18篇 |
1985年 | 26篇 |
1984年 | 17篇 |
1983年 | 24篇 |
1982年 | 23篇 |
1981年 | 22篇 |
1980年 | 31篇 |
1979年 | 15篇 |
1978年 | 13篇 |
1977年 | 29篇 |
1976年 | 36篇 |
1973年 | 14篇 |
1972年 | 13篇 |
1970年 | 12篇 |
排序方式: 共有2085条查询结果,搜索用时 11 毫秒
91.
Manindranath Bera Ghezai T. Musie Douglas R. Powell 《Inorganic chemistry communications》2010,13(9):1029-1031
A novel cyclic tetranuclear cluster, [Co(H2O)6][Co4(ccdp)2(H2O)4]·8H2O·2CH3CN (1) with cobalt(II) ions sitting in a quadrilateral has been synthesized and fully characterized by exploiting the flexibility, chelating ability and bridging potential of a carboxylate rich dinucleating ligand, H5ccdp [H5ccdp = N,N′-Bis[2-carboxybenzomethyl]-N,N′-Bis[carboxymethyl]-1,3-diaminopropan-2-ol]. The crystal structure of 1 contains a [Co4II(H2O)4)]2– core unit which is held together by two bridging benzoate potions of the ligands, ccdp5–. Furthermore, the [Co4II(H2O)4)]2– core unit is stabilized and charge neutralized by intermolecular hydrogen bonding and [Co(H2O)6]2+, respectively. 相似文献
92.
Constantin Turta Silvia Melnic Denis Prodius Fliur Macaev Helene Stoeckli-Evans Patricia Ruiz Dmitry Muraviev Serghei Pogrebnoi Zinaida Ribkovskaia Valeriu Mereacre Yanhua Lan Annie K. Powell 《Inorganic chemistry communications》2010,13(12):1402-1405
High-temperature solution phase reaction of iron(III)-furoate in sunflower oil, in the presence of trichloroacetic acid and 1,2-hexadecylamine leads to iron(III) oxide (amorphous and γ-Fe2O3) nanoparticles with sizes about 1.3 nm in diameter (method “A”), and about 5.5 nm (amorphous Fe2O3) from the “sunflower oil/oxadiazol” system (method “B”). 相似文献
93.
Corey Nelson Tyler Mrozowich Darren L. Gemmill Sean M. Park Trushar R. Patel 《International journal of molecular sciences》2021,22(1)
Flavivirus genus includes many deadly viruses such as the Japanese encephalitis virus (JEV) and Zika virus (ZIKV). The 5′ terminal regions (TR) of flaviviruses interact with human proteins and such interactions are critical for viral replication. One of the human proteins identified to interact with the 5′ TR of JEV is the DEAD-box helicase, DDX3X. In this study, we in vitro transcribed the 5′ TR of JEV and demonstrated its direct interaction with recombinant DDX3X (Kd of 1.66 ± 0.21 µM) using microscale thermophoresis (MST). Due to the proposed structural similarities of 5′ and 3′ TRs of flaviviruses, we investigated if the ZIKV 5′ TR could also interact with human DDX3X. Our MST studies suggested that DDX3X recognizes ZIKV 5′ TR with a Kd of 7.05 ± 0.75 µM. Next, we performed helicase assays that suggested that the binding of DDX3X leads to the unwinding of JEV and ZIKV 5′ TRs. Overall, our data indicate, for the first time, that DDX3X can directly bind and unwind in vitro transcribed flaviviral TRs. In summary, our work indicates that DDX3X could be further explored as a therapeutic target to inhibit Flaviviral replication 相似文献
94.
Ambreen Nisar Tyler Dolmetsch Tanaji Paul Cheng Zhang Benjamin Boesl Arvind Agarwal 《Journal of the American Ceramic Society》2021,104(6):2483-2494
The application of ultra-high-temperature ceramics (UHTCs) demands effective ways of joining in overcoming the problems associated with the fabrication of complex-shaped components. In this study, we choose to investigate a new method of rapidly joining pre-sintered TaC and HfC ceramics without any filler material using the spark plasma sintering (SPS) technique. A well-bonded TaC–HfC interface was observed with no apparent cracking and porosity at the joint. The joining mechanisms were predominantly driven by solid-state diffusion and localized plastic deformation. The nanomechanical properties of the TaC-HfC joint are better than the HfC while comparable to that of the TaC. High-load indentation (up to 200 N) results suggest that the TaC–HfC interface is stronger than the parent UHTCs with no crack propagating at the interface. Upon comparison with the parent UHTCs, the damaged area and the average crack length at the interface, reduced up to ~94% and ~56%, respectively. This study shows that the SPS technique can also apply to joining other UHTCs without any filler, resulting in the new field of developing complex components for the thermal protection system (TPS). 相似文献
95.
Corey R. Nelson Tyler Mrozowich Sean M. Park Simmone Dsouza Amy Henrickson Justin R. J. Vigar Hans-Joachim Wieden Raymond J. Owens Borries Demeler Trushar R. Patel 《International journal of molecular sciences》2021,22(1)
Rift Valley fever virus (RVFV) is a mosquito-transmitted virus from the Bunyaviridae family that causes high rates of mortality and morbidity in humans and ruminant animals. Previous studies indicated that DEAD-box helicase 17 (DDX17) restricts RVFV replication by recognizing two primary non-coding RNAs in the S-segment of the genome: the intergenic region (IGR) and 5′ non-coding region (NCR). However, we lack molecular insights into the direct binding of DDX17 with RVFV non-coding RNAs and information on the unwinding of both non-coding RNAs by DDX17. Therefore, we performed an extensive biophysical analysis of the DDX17 helicase domain (DDX17135–555) and RVFV non-coding RNAs, IGR and 5’ NCR. The homogeneity studies using analytical ultracentrifugation indicated that DDX17135–555, IGR, and 5’ NCR are pure. Next, we performed small-angle X-ray scattering (SAXS) experiments, which suggested that DDX17 and both RNAs are homogenous as well. SAXS analysis also demonstrated that DDX17 is globular to an extent, whereas the RNAs adopt an extended conformation in solution. Subsequently, microscale thermophoresis (MST) experiments were performed to investigate the direct binding of DDX17 to the non-coding RNAs. The MST experiments demonstrated that DDX17 binds with the IGR and 5’ NCR with a dissociation constant of 5.77 ± 0.15 µM and 9.85 ± 0.11 µM, respectively. As DDX17135–555 is an RNA helicase, we next determined if it could unwind IGR and NCR. We developed a helicase assay using MST and fluorescently-labeled oligos, which suggested DDX17135–555 can unwind both RNAs. Overall, our study provides direct evidence of DDX17135–555 interacting with and unwinding RVFV non-coding regions. 相似文献
96.
Lori N. Ivan Edward S. Rutherford Catherine Riseng Jeffrey A. Tyler 《Journal of Great Lakes research》2010
Walleye (Sander vitreus) is an important sport fish in the Great Lakes that is experiencing low reproductive success after severe population declines starting in the late 1940s. In the Muskegon River, Michigan, natural reproduction of walleyes remains low and is largely supplemented by stocking. To determine factors influencing walleye reproductive success in the Muskegon River, we estimated walleye egg survival using insitu egg incubators covered with nitex screening (2003–2004) and estimated density and survival of fertilized eggs caught on furnace filter traps across different substrate types (2005–2006). We compared physical habitat suitability for walleye eggs under high and low flow scenarios. Density of walleye eggs was highest in regions of gravel/cobble substrates. Egg survival was higher in egg incubators (24–49.5%) than on furnace filter traps (2.0%), suggesting predation is an important source of walleye egg mortality in the Muskegon River. Cold water temperatures that extended developmental stage durations may also be an important source of egg mortality. The dynamic habitat suitability model predicted low suitability for eggs due to poor temperature and velocity conditions. Despite low egg survival rates, 40 million to 1 billion eggs were estimated to hatch. The low natural reproduction of walleyes in the Muskegon River is likely due to a combination of low walleye egg survival and failure of walleye larvae to reach their nursery grounds in Muskegon Lake. 相似文献
97.
Alexander Gatch Dimitry Gorsky Zy Biesinger Eric Bruestle Kelley Lee Curt Karboski Meredith L. Bartron Tyler Wagner 《Journal of Great Lakes research》2021,47(2):486-493
Restoration of a wild-produced lake trout Salvelinus namaycush population in Lake Ontario has not been successful despite the adult population often meeting or exceeding restoration targets. Lack of high-quality spawning habitat in Lake Ontario is suggested as one impediment to recruitment of wild lake trout, although the quantity and location of spawning habitat is poorly understood. If high-quality spawning habitat is limited in Lake Ontario, lake trout may be using uncommon spawning locations such as rivers. Anecdotal angler accounts point to the Niagara River as a lake trout spawning location. To better understand the potential of the Niagara River as a spawning location, egg and juvenile fish collections were conducted 12–14 river kilometers from the mouth of the Niagara River from 2010 to 2012; and mature female lake trout with surgically implanted acoustic tags were monitored from 2015 to 2019. Genetic analyses confirmed 60% of collected eggs and 93% of collected post-hatch juvenile fish in the Niagara River were lake trout. Tagged female lake trout returned to the Niagara River over consecutive years during the spawning season. The short duration of lake trout presence in the river (mean = 56 days/year) suggests female lake trout use the Niagara River primarily for spawning. Diversity in spawning locations may provide lake trout population’s resilience against environmental variability through a portfolio effect. Improved identification of riverine spawning locations, including their overall contribution to wild recruitment, may be a useful tool for managers to restore a wild-produced population of lake trout in Lake Ontario. 相似文献
98.
Jarvis Tyler Clough Jordan Cox Jane Petersen Konnor Sailsbery Mitchell Robertson Connor Moncur Tyler Palmer Katie Lund Darren 《Water Resources Management》2021,35(2):745-756
Water Resources Management - A traditional cost-benefit analysis of potential water interventions in a given locality is a laborious and time-intensive process. To help decision makers identify... 相似文献
99.
An Objective Method to Prioritize Socio‐Environmental Water Management Tradeoffs Using Multi‐Criteria Decision Analysis 下载免费PDF全文
Rivers provide many social and environmental services that benefit humanity. A critical role of water mangers is to prioritize water allocation options that trade off socio‐economic and hydro‐ecological benefits in rivers. Methods for multi‐criteria decision analysis (MCDA) provide a structured and systematic manner for researchers to aid in this process. In this paper, we describe a new MCDA method that prioritizes large multi‐dimensional sets of tradeoffs to support well‐informed water management in rivers. The method was developed based on an environmental flows planning study in the Goulburn‐Broken River catchment, Victoria, Australia. A combined simulation and heuristic optimization procedure was previously integrated into a hydrological catchment network model. That process resulted in a large set of viable daily water allocation schedules that traded off long‐term irrigation and hydro‐ecological benefits at the catchment outlet. We provided new guidance procedures to identify priority tradeoffs that can be used in stakeholder deliberations and catchment decision‐making. Our MCDA method included combined multi‐dimensional ordination and cluster analysis to spread the water allocation alternatives onto a two‐dimensional plane to discover alternatives with similar criteria tradeoffs. A geometric distance‐based method was performed on the full set of alternatives and on the identified clusters to rank the alternatives in accordance with minimizing the distance of the alternatives to an ideal but non‐feasible reference point in multi‐dimensional space. This method complements the use of elicitation procedures when water manager or other stakeholder interaction is not an option or when objectivity is desired. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
100.
Thorpe KL Cummings RI Hutchinson TH Scholze M Brighty G Sumpter JP Tyler CR 《Environmental science & technology》2003,37(6):1142-1149
The natural steroids estradiol-17beta (E2) and estrone (E1) and the synthetic steroid ethynylestradiol-17alpha (EE2) have frequently been measured in waters receiving domestic effluents. All of these steroids bind to the estrogen receptor(s) and have been shown to elicit a range of estrogenic responses in fish at environmentally relevant concentrations. At present, however, no relative potency estimates have been derived for either the individual steroidal estrogens or their mixtures in vivo. In this study the estrogenic activity of E2, E1, and EE2, and the combination effects of a mixture of E2 and EE2 (equi-potent fixed-ratio mixture), were assessed using vitellogenin induction in a 14-day in vivo juvenile rainbow trout screening assay. Median effective concentrations, relative to E2, for induction of vitellogenin were determined from the concentration-response curves and the relative estrogenic potencies of each of the test chemicals calculated. Median effective concentrations were between 19 and 26 ng L(-1) for E2, 60 ng L(-1) for E1, and between 0.95 and 1.8 ng L(-1) for EE2, implying that EE2 was approximately 11 to 27 times more potent than E2, while E2 was 2.3 to 3.2 times more potent than E1. The median effective concentration, relative to E2, for the binary mixture of E2 and EE2 was 15 ng L(-1) (comprising 14.4 ng L(-1) E2 and 0.6 ng L(-1) EE2). Using the model of concentration addition it was shown that this activity of the binary mixture could be predicted from the activity of the individual chemicals. The ability of each individual steroid to contribute to the overall effect of a mixture, even at individual no-effect concentrations, combined with the high estrogenic potency of the steroids, particularly the synthetic steroid EE2, emphasizes the need to consider the total estrogenic load of these chemicals in our waterways. 相似文献