The long‐term effects of arteriovenous fistula creation on the development of pulmonary hypertension in hemodialysis patients

The aim of this prospective study was to evaluate long‐term effects of arteriovenous fistula (AVF) on the development of pulmonary arterial hypertension (PAH) and the relationship between blood flow rate of AVF and pulmonary artery pressure (PAP) in the patients with end‐stage renal disease (ESRD). This prospective study was performed in 20 patients with ESRD. Before an AVF was surgically created for hemodialysis, the patients were evaluated by echocardiography. Then, an AVF was surgically created in all patients. After mean 23.50 ± 2.25 months, the second evaluation was performed by echocardiography. Also, the blood flow rate of AVF was measured at the second echocardiographic evaluation. Pulmonary arterial hypertension was defined as a systolic PAP above 35 mmHg at rest. Mean age of 20 patients with ESRD was 55.05 ± 13.64 years; 11 of 20 patients were males. Pulmonary arterial hypertension was detected in 6 (30%) patients before AVF creation and in 4 (20%) patients after AVF creation. Systolic PAP value was meaningfully lower after AVF creation than before AVF creation (29.95 ± 10.26 mmHg vs. 35.35 ± 7.86 mmHg, respectively, P: 0.047). However, there was no significant difference between 2 time periods in terms of presence of PAH (P>0.05). Pulmonary artery pressure did not correlate with blood flow rate of AVF and duration after AVF creation (P>0.05). In hemodialysis patients, a surgically created AVF has no significant effect on the development of PAH within a long‐term period. Similarly, blood flow rate of AVF also did not affect remarkably systolic PAP within the long‐term period.     

Computation of the exact Cramer–Rao lower bound for the parameters of a nonsymmetric half-plane 2-D ARMA model

The Cramer–Rao lower bound (CRLB) that gives the minimal achievable variance/standard deviation for any unbiased estimator offers a useful tool for an assessment of the consistency of parameter estimation techniques. In this paper, a closed-form expression for the computation of the exact CRLB on unbiased estimates of the parameters of a two-dimensional (2-D) autoregressive moving average (ARMA) model with a nonsymmetric half-plane (NSHP) region of support is developed. The proposed formulation is mainly based on a matrix representation of 2-D real-valued discrete and homogeneous random field characterized by the NSHP ARMA model. Assuming that the random field is Gaussian, the covariance matrix of the NSHP ARMA random field is first expressed in terms of the model parameters. Then, using this matrix structure, a closed-form expression of the exact Fisher information matrix required for the CRLB computation of the NSHP ARMA model parameters is developed. Finally, the main formulas derived for the NSHP ARMA model are rearranged for its autoregressive and moving average counterparts, separately. Numerical simulations are included to demonstrate the behavior of the derived CRLB formulas.     

Intercomparison of the Realizations of the ITS-90 from 83.8058 K to 692.677 K among European NMIs

The EUROMET.T-K3 comparison is the regional extension of CCT-K3. The comparison involved the six European national metrology institutes (NMIs) previously involved in CCT-K3 (LNE-INM/CNAM, SMU, INRiM, NMi-VSL, NPL, PTB) and 18 additional European national laboratories. The comparison was divided into five different loops, each coordinated by a co-pilot chosen from the laboratories having participated in the CCT-K3 comparison. LNE-INM/CNAM played the role of pilot in linking the five loops. In each loop, an artifact in the form of a standard platinum resistance thermometer (SPRT, 25 Ω) was circulated among the participating laboratories. To have sufficient information about the possible drift of the SPRTs, the co-pilots performed a calibration over the full temperature range at the beginning and at the end of the loop. A EUROMET reference value (ERV), taking into account the whole comparison, was defined, and the differences (T _Lab − T _ERV) were calculated with the associated uncertainties. The method for establishing the link between the participants in CCT-K3 and in EUROMET.T-K3 is described. Institut National de Métrologie (BNM-INM/CNAM at the time of the comparison, LNE-INM/CNAM since 1 January 2005), Paris, France.     

Efficiency improvement and NOx emission reduction potentials of two‐stage turbocharged Miller cycle for stationary natural gas engines

As a part of an engine research and development project in cooperation with industry, a V20 engine is designed with two‐stage high‐pressure turbocharging, and the potential of the Miller cycle is examined through calculations using computational models based on experimental as well as computational studies. The stationary gas engines must produce less than 250 mg Nm^?3 in 5% excess of O₂, additionally the amount of NO_x emissions and their dependence on engine operational and design conditions are investigated by using a zero‐dimensional reaction kinetic model. The results show an increase in efficiency, also the amount of NO_x emissions is kept under the constraint value of 250 mg Nm^?3 for stationary engines. The results obtained here promise a very high improvement potential for future emission regulations. Copyright © 2004 John Wiley & Sons, Ltd.     

Determination of flavan-3-ols and trans-resveratrol in grapes and wine using HPLC with fluorescence detection

Concentrations of trans-resveratrol, catechin and epicatechin were analyzed in musts and wines produced from seven red and four white grape cultivars from various wine growing regions of Turkey. Phenolics were quantified using an HPLC method optimized for the separation of wine phenolics. Wine samples contained higher phenolics levels than the corresponding musts. With the exception of Semillion, white wines and musts contained lower concentrations of phenolics than red wines and musts. However, the white cultivar Semillion had the highest concentrations of catechin and epicatechin among all wine and must samples. Semillion wine catechin and epicatechin were 13.7 and 11.8 mg/L, respectively. The highest level of trans-resveratrol among the white cultivars was found in Narince wine (1.93 mg/L). Within the red wine and must cultivars, Bo?azkere, Öküzgozü, and Cabernet contained the highest concentrations of flavan-3-ols and trans-resveratrol. Catechin was the major phenolic in all wines and most musts. Epicatechin was the major phenolic in 6 of the 11 must samples, but none of the wine samples. trans-Resveratrol was generally found in lowest concentrations in both wines and musts.     

Influence of temperature on fast-mode cyclic operation hydrodynamics in trickle-bed reactors

Despite the merits of periodic operation praised in the academic literature as one of the process intensification strategies advocated for trickle-bed reactors (TBRs), there is still reluctance to implement it in industrial practice. This can partly be ascribed to the lack of engineering data relevant to the elevated temperature and pressure characterizing industrial processes. Currently, the hydrodynamics of trickle beds under cyclic operation, especially in fast mode at elevated temperature and pressure, remains by and large terra incognita. This study proposes exploration of the hydrodynamic behavior of TBRs experiencing fast liquid flow modulation at elevated temperature and moderate pressure. The effect of temperature and pressure on the liquid holdup and pressure drop time series in terms of pulse breakthrough and decay times, pulse intensity and pulse velocity was examined for a wide range of superficial gas and liquid (base and pulse) velocities for the air-water system. The pulse breakthrough and decay times decreased, whereas the pulse velocity increased with temperature and/or pressure. The pressure drop was attenuated with increasing temperature for a given superficial gas, and base and pulse superficial liquid velocities. Experimental pulse velocity values were compared to the Giakoumakis et al. [2005. Induced pulsing in trickle beds—characteristics and attenuation of pulses. Chemical Engineering Science 60, 5183-5197] correlation which revealed that it could be relied upon at elevated temperature and close to atmospheric pressure.     

Rheological and fusion behaviors of PVC micro‐ and nano‐composites evaluated from torque rheometer data

The effects of calcium carbonate (CaCO₃) particle size on the fusion and rheological behaviors of rigid poly(vinyl chloride) (PVC) composites prepared in a Haake torque rheometer were investigated by means of torque data recorded during processing. Increasing the number of particles in the same blend volume by decreasing the particle size resulted in increasing frictional forces. This increase led in turn to increased fusion torque and decreased fusion time and temperature. The power‐law‐index values of the composites increased with decreasing particle size except for 25‐nm CaCO₃. The viscosities of all composites were found to decrease with shear rate; therefore, high pseudoplasticity was observed. At a particular rotor speed, viscosity of the composites decreased with decreasing particle size except for 25‐nm CaCO₃. The overall results showed that the particle size of CaCO₃ altered the fusion characteristics and rheological behavior of PVC. J. VINYL ADDIT. TECHNOL., 2010. © 2010 Society of Plastics Engineers     

An approach for automated fault diagnosis based on a fuzzy decision tree and boundary analysis of a reconstructed phase space

Although reconstructed phase space is one of the most powerful methods for analyzing a time series, it can fail in fault diagnosis of an induction motor when the appropriate pre-processing is not performed. Therefore, boundary analysis based a new feature extraction method in phase space is proposed for diagnosis of induction motor faults. The proposed approach requires the measurement of one phase current signal to construct the phase space representation. Each phase space is converted into an image, and the boundary of each image is extracted by a boundary detection algorithm. A fuzzy decision tree has been designed to detect broken rotor bars and broken connector faults. The results indicate that the proposed approach has a higher recognition rate than other methods on the same dataset.