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排序方式: 共有230条查询结果,搜索用时 15 毫秒
31.
32.
Karl-Ernst Hensger Peter Klimanek Ulla Trinks Ullrich Martin Klaus Cyrener 《国际钢铁研究》1991,62(3):124-130
Die Arbeit leistet unter Verwendung eines ferritischen und eines austenitischen Stahls (X 8 CrTi 17, X 8 CrNiTi 18 10) einen Beitrag zur Charakterisierung der Realstrukturveränderungen bei Warmumformung im Kaliber. Die Kaliberumformung rund-oval erfolgt in einem Modellversuch – dem Kaliberstauchen – und durch Kaliberwalzen mit Umformgeschwindigkeiten zwischen 1 und 4 000 s?1. Die bei Kaliberstauchen und -walzen eintretenden Realstrukturveränderungen stimmen gut überein. Bei Umformtemperaturen ≦800°C erfolgt in beiden Werkstoffen keine Rekristallisation; die Versetzungsdichte ist hoch (1010–1011 cm?2). In der Orientierungsverteilungsfunktion dominieren die typischen Komponenten der Kalibertextur. Es wird die Gefügeentwicklung längs der Warmfließkurve untersucht (800 °C, 4 000 s?1). Für den ferritischen Stahl dominiert polygonisiertes Subgefüge, während im austenitischen Stahl eine Zellstruktur vorherrscht. 相似文献
33.
Arshinov Y Bobrovnikov S Serikov I Ansmann A Wandinger U Althausen D Mattis I Müller D 《Applied optics》2005,44(17):3593-3603
We propose to use a Fabry-Perot interferometer (FPI) in a pure rotational Raman lidar to isolate return signals that are due to pure rotational Raman scattering from atmospheric nitrogen against the sky background. The main idea of this instrumental approach is that a FPI is applied as a frequency comb filter with the transmission peaks accurately matched to a comb of practically equidistant lines of a pure rotational Raman spectrum (PRRS) of nitrogen molecules. Thus a matched FPI transmission comb cuts out the spectrally continuous sky background light from the spectral gaps between the PRRS lines of nitrogen molecules while it is transparent to light within narrow spectral intervals about these lines. As the width of the spectral gaps between the lines of the PRRS of nitrogen molecules is -114 times the width of an individual spectral line, cutting out of the sky background from these gaps drastically improves the signal-to-background ratio of the pure rotational Raman lidar returns. This application of the FPI enables one to achieve daytime temperature profiling in the atmosphere with a pure rotational Raman lidar in the visible and near-UV spectral regions. We present an analysis of application of the FPI to filtering out the pure rotational Raman lidar returns against the solar background. To demonstrate the feasibility of the approach proposed, we present temperature profiles acquired during a whole-day measurement session in which a Raman lidar equipped with a FPI was used. For comparison, temperature profiles acquired with Vaisala radiosondes launched from the measurement site are also presented. 相似文献
34.
Hammer NA Hansen Tv Byskov AG Rajpert-De Meyts E Grøndahl ML Bredkjaer HE Wewer UM Christiansen J Nielsen FC 《Reproduction (Cambridge, England)》2005,130(2):203-212
Insulin-like growth factor-II mRNA-binding proteins 1, 2 and 3 (IMP1, IMP2 and IMP3) belong to a family of RNA-binding proteins implicated in mRNA localization, turnover and translational control. We examined their expression pattern during development of murine and human testis and ovaries. In the mouse, IMPs were expressed in male and female gonadal cells at embryonic day 12.5 (E12.5). From E16.5, IMP1 and IMP3 became restricted to the developing germ cells, whereas IMP2 expression persisted in the interstitial cells. In mature mouse and human ovaries, IMP1, IMP2 and IMP3 were detected in resting and growing oocytes and in the granulosa cells. In testis, IMP1 and IMP3 were found mainly in the spermatogonia, whereas IMP2 was expressed in the immature Leydig cells. Moreover, all three IMPs were detected in human semen. The developmental expression pattern of IMP1 and IMP3 in the human testis prompted us to examine their possible involvement in testicular neoplasia. IMPs were detected primarily in germ-cell neoplasms, including preinvasive testicular carcinoma in situ, classical and spermatocytic seminoma, and nonseminomas, with particularly high expression in undifferentiated embryonal carcinoma. The relative expression of IMP1, IMP2 and IMP3 varied among tumor types and only IMP1 was detected in all carcinoma in situ cells. Thus IMPs, and in particular IMP1, may be useful auxiliary markers of testicular neoplasia. 相似文献
35.
36.
Stennicke Henning R.; Mortensen Uffe H.; Christensen Ulla; Remington S.James; Breddam Klaus 《Protein engineering, design & selection : PEDS》1994,7(7):911-916
Carboxypeptidase Y is a serine carboxypeptidase isolated fromSaccharomyces cerevisiae with a preference for Cterminal hydrophobicamino acid residues. In order to alter the inherent substratespecificity of CPD-Y into one for basic amino acid residuesin P'1, we have introduced Asp and/or Glu residues at a numberof selected positions within the Si binding site. Hie effectsof these substitutions on the substrate specificity, pH dependenceand protein stability have been evaluated. The results presentedhere demonstrate that it is possible to obtain significant changesin the substrate preference by introducing charged amino acidsinto the framework provided by an enzyme with a quite differentspecificity. The introduced acidic amino acid residues providea marked pH dependence of the (kcat/Km)FA-A-R-OH/(kcatm)FA-A-R-OHratio. The change in stability upon introduction of Asp/Gluresidues can be correlated to the difference in the mean buriedsurfac surface area between the substituted and the substitutingamino acid. Thus, the effects of acidic amino acid residueson the protein stability depend upon whether the introducedamino acid protrudes from the solvent accessible surface asdefined by the surrounding residues in the wild type enzymeor is submerged below. 相似文献
37.
Small droplets appearing on the surface of alkali-silica reactive aggregates and on gel in cracks and air voids have been observed during microscopy of polished thin sections. On aggregates, the droplets are generally only observed if quartz is the major component. The location of the droplets in these aggregates are on and along the grain boundaries of quartz subgrains. The composition of droplets located on quartz and on “crystalline gel” has been analysed by SEM. The droplets on quartz consist mainly of sodium and minor potassium. The droplets on “crystalline gel” are rich in both sodium and potassium. Calcium is generally absent and silica low in all types of droplets. It is suggested that the droplets represent the liquid phase in equilibrium with the reaction product formed by alkali-silica reaction. 相似文献
38.
Masakazu Umezawa Atsuto Onoda Irina Korshunova Alexander C. Ø. Jensen Ismo K. Koponen Keld A. Jensen Konstantin Khodosevich Ulla Vogel Karin S. Hougaard 《Particle and fibre toxicology》2018,15(1):36
Background
Engineered nanoparticles are smaller than 100 nm and designed to improve or creating even new physico-chemical properties. Consequently, toxicological properties of materials may change as size reaches the nm size-range. We examined outcomes related to the central nervous system in the offspring following maternal inhalation exposure to nanosized carbon black particles (Printex 90).Methods
Time-mated mice (NMRI) were exposed by inhalation, for 45 min/day to 0, 4.6 or 37 mg/m3 aerosolized carbon black on gestation days 4–18, i.e. for a total of 15 days. Outcomes included maternal lung inflammation (differential cell count in bronchoalveolar lavage fluid and Saa3 mRNA expression in lung tissue), offspring neurohistopathology and behaviour in the open field test.Results
Carbon black exposure did not cause lung inflammation in the exposed females, measured 11 or 28–29 days post-exposure. Glial fibrillary acidic protein (GFAP) expression levels were dose-dependently increased in astrocytes around blood vessels in the cerebral cortex and hippocampus in six weeks old offspring, indicative of reactive astrogliosis. Also enlarged lysosomal granules were observed in brain perivascular macrophages (PVMs) in the prenatally exposed offspring. The number of parvalbumin-positive interneurons and the expression levels of parvalbumin were decreased in the motor and prefrontal cortices at weaning and 120 days of age in the prenatally exposed offspring. In the open field test, behaviour was dose-dependently altered following maternal exposure to Printex 90, at 90 days of age. Prenatally exposed female offspring moved a longer total distance, and especially males spent significantly longer time in the central zone of the maze. In the offspring, the described effects were long-lasting as they were present at all time points investigated.Conclusion
The present study reports for the first time that maternal inhalation exposure to Printex 90 carbon black induced dose-dependent denaturation of PVM and reactive astrocytes, similarly to the findings observed following maternal exposure to Printex 90 by airway instillation. Of note, some of the observed effects have striking similarities with those observed in mouse models of neurodevelopmental disorders.39.
Andreas W. Sonesson Thomas H. Callisen Ulla M. Elofsson Hjalmar Brismar 《Journal of surfactants and detergents》2007,10(4):211-218
Detergency mechanisms of lipids from single cotton fibers were visualized by means of confocal laser scanning microscopy (CLSM).
Fibers were soiled with different types of lipids: olive oil, lard and tri-C10, and subsequently stained with the fluorescent probe Nile Red. A surfactant composition of 300 μM C12E6/LAS (1:2 mol%) was used to mimic the surfactants used in a common washing solution. It was evident from the captured image
series that the different kinds of soiling were removed by different mechanisms by the surfactants, depending on the fluidity
of the lipid. Roll-up was the main mechanism when removing olive oil, whereas emulsification (necking) and/or solubilization
were observed in the removal of lard and tri-C10. Only 20–25% of the olive oil remained after treatment with surfactants, which was much less compared to the solid fats where
roughly 50% remained at end of treatment. The effect of adding lipases to the detergent formulation was clearly seen, both
by an apparently higher rate of removal of olive oil but also using double injection when removing lard. A first injection
of only surfactants removed a certain part of the lard as emulsion droplets stuck onto the fiber. A second injection of both
lipases and surfactants was able to remove some of the preformed emulsion particles and reduce the overall remaining lard
content on the cotton fiber.
相似文献
Thomas H. CallisenEmail: |
40.
Karina Jensen Lars P Christensen Merete Hansen Ulla Jrgensen Karl Kaack 《Journal of the science of food and agriculture》2001,81(2):237-244
Aroma compounds emitted from elderberry juices processed from seven cultivars were collected by the dynamic headspace technique and analysed by GC–FID and GC–MS. Forty aroma compounds were identified and quantified, including nine compounds which had not previously been detected in elderberry juice. Significant differences were found among cultivars in the concentration levels of 30 compounds. The sensory characteristics of the individual aroma compounds in elderberry juice were determined by a GC‐sniffing technique, and the compounds were grouped according to their odour. The characteristic elderberry odour is due to dihydroedulan and β‐damascenone, of which the former occurs in relatively high concentrations in the headspace of elderberry juice. The fruity group consisted of aliphatic alcohols and aldehydes and aromatic esters, of which 1‐pentanal, 2‐methyl‐1‐propanol, 2‐ and 3‐methyl‐1‐butanol, 1‐octanal, 1‐octanol and methyl and ethyl benzoate contributed with fruity notes. In the flowery group, 1‐nonanal, nerol oxide and (Z)‐ and (E)‐rose oxide contributed with characteristic elder flower odour, whereas other flowery notes were associated with hotrienol, linalool and α‐terpineol. Fresh and grassy odours were correlated with 1‐hexanal, (E)‐2‐hexen‐1‐al, (Z)‐3‐hexen‐1‐ol, (E)‐2‐hexen‐1‐ol and (E)‐2‐octen‐1‐al of the grassy group, whereas 1‐octen‐3‐ol and 1‐octen‐3‐one of the agrestic group contributed significantly with the characteristic aroma of mushrooms. © 2000 Society of Chemical Industry 相似文献