Determination of diquat and paraquat in olive oil by ion-pair liquid chromatography–electrospray ionization mass spectrometry (MRM)

For the first time a method for determination of herbicides diquat (DQ) and paraquat (PQ) in olive oil was developed utilising liquid chromatography–electrospray ionization mass spectrometry (MRM). n-Hexane/10 mM HFBA aqueous solution partitioning was used as the extraction method. Separation was carried out in an Xterra C8 column (100 × 21 mm, 3 μm), using the gradient mode. Solvent A was a HFBA aqueous solution (5 mM, pH 2) and solvent B acetonitrile/methanol 75/25 (v/v). Peaks used for quantification were m/z = 157 (diquat) and m/z = 158 (paraquat). Detection limit found for both diquat and paraquat was 4 μg kg⁻¹. The method can also be applied for determination of chlormequat (CQ, quantification peak m/z = 58), the detection limit being 0.3 μg kg⁻¹. Such limits are clearly lower than the MCLs commonly applied to olive oil as reference criteria (5 times MCLs in olives). Good reproducibilities (day to day and run to run) were obtained.     

Influence of hydrocortisone acetate of the longissimus dorsi muscle during gestation of rats

The evolution in detail of the N retention during gestation was studied, dividing it in short periods of time, and how that retention affects Longissimus dorsi muscle. Simultaneously, the same study in pregnant rats treated with hydrocortisone acetate was done. During gestation N balance maintains high values that tend to increase at days 18 to 21. The greatest metabolic utilization of the N dietary corresponds to this period in which the percentage of the N retained in relation to the N absorbed is markedly higher than in previous days of gestation. In spite of the excellent quality and adequate concentration of protein in the diet, the administration of 4 mg/100 g weight and day of hydrocortisone acetate maintains the pregnant rat in a negative balance until day 18, as a consequence of the decrease in food intake and faecal and urinary N losses. From day 18 to day 21 of gestation the balance of N increases and the metabolic utilization of the dietary N is similar between pregnant rats injected with NaCl 0.9% and pregnant rats injected with hydrocortisone acetate. The Longissimus dorsi normal growth pattern (in relation to weight and N content) in young adult rats is not modified by gestation. The catabolic effects of hydrocortisone acetate on Longissimus dorsi muscle in pregnant rats can be observed from day 9 of treatment. The longer the treatment the higher the effect is.     

Catalytic Performance and Sulfur Dioxide Resistance of One-Pot Synthesized Fe-MCM-22 in Selective Catalytic Reduction of Nitrogen Oxides with Ammonia (NH3-SCR)—The Effect of Iron Content

The catalytic performance of Fe-catalysts in selective catalytic reduction of nitrogen oxides with ammonia (NH₃-SCR) strongly depends on the nature of iron sites. Therefore, we aimed to prepare and investigate the catalytic potential of Fe-MCM-22 with various Si/Fe molar ratios in NH₃-SCR. The samples were prepared by the one-pot synthesis method to provide high dispersion of iron and reduce the number of synthesis steps. We have found that the sample with the lowest concentration of Fe exhibited the highest catalytic activity of ca. 100% at 175 °C, due to the abundance of well-dispersed isolated iron species. The decrease of Si/Fe limited the formation of microporous structure and resulted in partial amorphization, formation of iron oxide clusters, and emission of N₂O during the catalytic reaction. However, an optimal concentration of Fe_xO_y oligomers contributed to the decomposition of nitrous oxide within 250–400 °C. Moreover, the acidic character of the catalysts was not a key factor determining the high conversion of NO. Additionally, we conducted NH₃-SCR catalytic tests over the samples after poisoning with sulfur dioxide (SO₂). We observed that SO₂ affected the catalytic performance mainly in the low-temperature region, due to the deposition of thermally unstable ammonium sulfates.     

The impact of biophilic design in Maggie’s Centres: A meta-synthesis analysis

This paper presents a meta-synthesis conducted to identify, compare and synthesize published qualitative data related to the Maggie's Centres, as a paradigmatic architectural example in the provision of non-institutional cancer support. These centres are internationally renowned for their unique architecture, where the careful design of indoors and outdoors spaces plays a critical role in their agenda for supporting care. Previous research has thoroughly analysed this approach to therapeutic environments, not only confirming the importance of designed space as originally conceived in Maggie's philosophy but also identifying precise supporting effects associated with specific elements within their design. This paper aims to provide a new reading of Maggie's contribution to cancer support by offering an examination of all these data through the lens of biophilia, which clarifies the impact of design decisions connected to nature on cancer patients' lives. The analytic process included a systematic search strategy, extraction and classification of salient concepts using an open-coding approach, and lastly an interpretive evaluation. The systematically selected data helped to identify and rank the biophilic design parameters that appear the most critical for promoting and supporting human health and wellbeing in non-clinical therapeutic environments, from the user's perspective. It also provided a compilation of distinctive design interventions related to biophilic parameters, which provides benchmark information for future research and design guidance in these environments.