Effects of triiodothyronine (T3) supplementation upon ozone-induced lung injury

Ozone exposure results in an acute decrease in the serum levels of thyroid hormones; the physiologic sequelae of this are unclear. Whereas thyroid hormone supplementation appears to benefit pulmonary function in septic, oxyradical models of injury, thyroid hormone increases ozone toxicity. We demonstrated an increase in metabolic rate and pulmonary injury in lungs from ozone exposed, T3 treated animals. This was evidenced by an increase in pulmonary weight gain, vascular perfusion pressure, and decrease in compliance in the supplemented animals. However, an increase in alkane generation, as an index of lipid peroxidation, was not seen in the ozone exposed, hormonally treated animals. This suggests that although thyroid hormone supplementation increases metabolic rate and ozone toxicity, an increased rate of lipid peroxidation plays a minimal role.     

Use of recursive methods in fuzzy fault tree analysis: an aid to quantitative risk analysis

This paper demonstrates the use of recursive techniques in quantitative risk analysis when the probability of occurrence of the basic events is uncertain (fuzzy) in nature instead of having a precise value. Cases of both coherent and non-coherent fault trees with replicated events are dealt with. The analyses have been computerized using an IBM compatible personal computer (PC-AT). The source code is in C and uses Turbo-C graphics routines for creating plots. A wide variety of examples with different membership functions have been considered.     

交流·阅读文稿·互动——书籍整体设计伊始的两个重要环节

忽视书籍整体设计前与写作者的交流、阅读文稿这两个环节,无疑会对设计过程造成很大的设计障碍。“限制”与“反限制”于当代设计中是设计师所必须要面临的现实问题。克服被“限制”的思维定式,以“限制”为设计创想的起始点,使设计更准确地表现被设计物的气质,同时又能充分表现设计师独具的设计表现风貌、协助销售,使设计与销售达成双赢的结果,此为时代要求使然。     

车辆生产中军转民有关问题探讨

本文指出了从军用车辆生产转向民用车辆生产是一个技术与经济的过程；论述了尽快完成这一过程所必须解决的技术创新问题，生产方式问题和投资多元化问题．     

What decides: high mortality in paediatric acute renal failure?

Forty paediatric cases of A.R.F. (Acute Renal Failure) of various aetiology were included in the study. 60% of patients were less than 4 years of age with male predominance. 80% cases reported to us very late with oligoanuria of more than 24 hours (2-7 days). Diarrhoea, vomiting and fever were other dominant symptoms. Maximum cases were severely anaemic (87.5%) with mean Hb 7.73 +/- 1.9 gm%. 40% cases were of underweight while only one case (2.5%) was of over weight, inspite of volume excess in 40% cases. All 24 cases, who were estimated for serum albumin, found to have marked hypoalbuminemia. Mortality was found to be as high as 65% inspite of effective peritoneal dialysis in all cases. High mortality seems to be due to profound anuria of many days (because of marked delay in reaching the hospital), fever and malnutrition besides other factors as aetiology.