Large-deviation inequalities for parameter estimators in stochastic systems

Translated from Kibernetika i Sistemnyi Analiz, No. 2, pp. 95–112, March–April, 1994.     

First break refraction event picking using fuzzy logic systems

First break picking is a pattern recognition problem in seismic signal processing, one that requires much human effort and is difficult to automate. The authors' goal is to reduce the manual effort in the picking process and accurately perform the picking. Feedforward neural network first break pickers have been developed using backpropagation training algorithms applied either to an encoded version of the raw data or to derived seismic attributes which are extracted from the raw data. The authors summarize a study in which they applied a backpropagation fuzzy logic system (BPFLS) to first break picking. The authors use derived seismic attributes as features, and take lateral variations into account by using the distance to a piecewise linear guiding function as a new feature. Experimental results indicate that the BPFLS achieves about the same picking accuracy as a feedforward neural network that is also trained using a backpropagation algorithm; however, the BPFLS is trained in a much shorter time, because there is a systematic way in which the initial parameters of the BPFLS can be chosen, versus the random way in which the weights of the neural network are chosen     

Assessment of annihilation anxiety from projective tests

This report details procedures to measure annihilation anxiety, a concept derived from Freud's 1926 formulation of traumatic anxiety. A 25-item pencil-and-paper inventory administered to patient and to nonpatient samples is described, along with a brief summary of earlier findings. The delineation of nine interrelated experiential components of annihilation anxiety provides the background for the construction of Rorschach and TAT measures of the concept. Findings comparing the pencil-and-paper inventory and the projective test measures are presented as well as examples of responses judged to reflect annihilation anxiety from Rorschach and TAT protocols.     

Potentiation of tumour necrosis factor-mediated cell killing by VP16 on human ovarian cancer cell lines. In vitro results and clinical implications

Synergism between recombinant human tumour necrosis factor (rHuTNF) and DNA topoisomerase II inhibitor VP16 during the killing of cells has been studied in six human ovarian cancer cell lines (A2774, A2780, SW626, IGROV-1, SKOV3, Pa1) and a cervical carcinoma cell line (Me180). Studies were performed using an assay of colony formation inhibition (drug treatment for 1 h) and a growth inhibition assay (continuous exposure for 20 h). Concomitant treatment of cells with VP16+rHuTNF enhanced cell killing in all the cell lines tested--an effect observed in both short- and long-term cytotoxicity assays. This study suggests that the activity of VP16 in ovarian cancer cell lines might be enhanced by rHuTNF in in vitro models.     

Two cell-wall-associated aminopeptidases from Lactobacillus helveticus and the purification and characterization of APII from strain ITGL1

Lactobacillus helveticus ITGL1 is able to hydrolyse many amino-acyl and dipeptidyl-p-nitroanilides. Analysis of heat inactivation kinetics, metal ion and protease inhibitor effects, and the subcellular location of aminopeptidase activities in both the parental strain and mutants deficient in lysyl-p-nitroanilide hydrolysis, led to the characterization of two cell-wall-associated aminopeptidases, APII and APIV. APII, which catalysed L-lysine p-nitroanilide hydrolysis, was purified about 28-fold to homogeneity from cell-wall extracts of L. helveticus ITGL1 and characterized. The purified enzyme appeared to be monomeric, with a molecular mass of 97 kDa. Aminopeptidase activity was greatest at pH 6.5 and 50 degrees C. APII was completely inhibited by bestatin, chelating agents such as EDTA or 1,10-phenanthroline and the divalent cations Zn2+ and Cu2+. The activity of the EDTA-treated enzyme was restored by Co2+, Ca2+ or Mn2+. Although APII was able to degrade several dipeptides and tripeptides with hydrophobic N-terminal amino acid (Leu, Ala), it was inactive on peptides containing Pro or Gly, and may thus contribute to the development of cheese flavour by processing bitter peptides.     

The use of patent titles for identifying the topics of invention and forecasting trends

Co-word analysis applied to patents through WPIL normalized title words appears to give a useful picture of a given field: we obtain both qualitative (themes) and quantitative information (weight of themes). It also gives information about the strategic aspects of the themes. Furthermore, in some cases, it is an indication of the future of certain themes that may help forecasting and management studies. Finally, it provides information about what could be a real technology growth process, in relation to the so-called translation model used in co-word analysis.     

Some features of the chemical transformation of a highly exothermic ore concentrate-based mixture in a combustion wave

Use of inexpensive ore concentrates as initial components in SHS metallurgy [1–3] brings about some specific features in the process and the properties of the materials obtained. Ore reagents contain a considerable amount of impurities (Al₂O₃, SiO₂, Fe₂O₃) that decrease the energetics of SHS systems and the temperature and the rate of combustion and create the limits of combustion and phase separation. In addition, the impurities participate in chemical reactions and enter the desired product. In many cases the presence of silicon, iron, and aluminum in a cast product does not prevent use of this product for practical purposes.Institute of Metallurgy, Academy of Sciences of the Republic of Georgia, Tbilisi. Institute of Structural Macrokinetics, Russian Academy of Sciences, Chernogolovka. Translated from Inzhenerno-Fizicheskii Zhurnal, Vol. 65, No. 5, pp. 613–616, November, 1993.