Collisions at rail level crossings (RLXs) are typically high-severity and high-cost, often involving serious injuries, fatalities and major disruptions to the transport network. Most research examining behaviour at RLXs has focused exclusively on drivers and consequently there is little knowledge on how other road users make decisions at RLXs. We collected drivers’, motorcyclists’, bicyclists’ and pedestrians’ self-reported daily experiences at RLXs for two weeks, focusing on behaviour, decision-making and information use in the presence of a train and/or activated RLX signals. Both information use and behaviour differed between road users. Visual information (e.g. flashing lights) was more influential for motorists, whereas pedestrians and cyclists relied more on auditory information (e.g. bells). Pedestrians were also more likely to violate active RLX warnings and/or cross before an approaching train. These results emphasise the importance of adopting holistic RLX design approaches that support cognition and behaviour across for all road users.
Practitioner Summary: This study explores how information use and decision-making at rail level crossings (RLXs) differ between road user groups, using a two-week self-report study. Most users make safe decisions, but pedestrians are most likely to violate RLX warnings. Information use (visual vs. auditory) also differs substantially between road user groups. 相似文献
In the past, lane departure warnings (LDWs) were demonstrated to improve driving behaviours during lane departures but little is known about the effects of unreliable warnings. This experiment focused on the influence of false warnings alone or in combination with missed warnings and warning onset on assistance effectiveness and acceptance. Two assistance unreliability levels (33 and 17%) and two warning onsets (partial and full lane departure) were manipulated in order to investigate interaction. Results showed that assistance, regardless unreliability levels and warning onsets, improved driving behaviours during lane departure episodes and outside of these episodes by favouring better lane-keeping performances. Full lane departure and highly unreliable warnings, however, reduced assistance efficiency. Drivers’ assistance acceptance was better for the most reliable warnings and for the subsequent warnings. The data indicate that imperfect LDWs (false warnings or false and missed warnings) further improve driving behaviours compared to no assistance.
Practitioner Summary: This study revealed that imperfect lane departure warnings are able to significantly improve driving performances and that warning onset is a key element for assistance effectiveness and acceptance. The conclusion may be of particular interest for lane departure warning designers. 相似文献
Widespread use of GPS and similar technologies makes it possible to collect extensive amounts of trajectory data. These data sets are essential for reasonable decision making in various application domains. Additional information, such as events taking place along a trajectory, makes data analysis challenging, due to data size and complexity. We present an integrated solution for interactive visual analysis and exploration of events along trajectories data. Our approach supports analysis of event sequences at three different levels of abstraction, namely spatial, temporal, and events themselves. Customized views as well as standard views are combined to form a coordinated multiple views system. In addition to trajectories and events, we include on-the-fly derived data in the analysis. We evaluate our integrated solution using the IEEE VAST 2015 Challenge data set. A successful detection and characterization of malicious activity indicate the usefulness and efficiency of the presented approach. 相似文献
ABSTRACTPrevious research on personal health records (PHRs) has focused on applications that are “tethered” to a specific electronic health record (EHR). However, there is a gap in research on the usability of unaffiliated, independent PHRs, as well as research on college-aged PHR users. Therefore, we performed a comparative usability study with 18 college-aged participants on three popular, freely available, independent PHRs. Participants completed the same six tasks in three different PHRs. Dependent variables included task time, mouse movement, mouse clicks, keystrokes, errors, and user satisfaction ratings based on the Computer System Usability Questionnaire (CSUQ). Analysis of variance (ANOVA) was used to determine the significance in the difference of the means for each dependent variable. Results showed statistically significant differences in CSUQ survey categories, errors, and keystrokes. Results supported one of the three PHRs (“System A”) as having better usability than its tested counterparts; participants scored best in System A of all categories of the CSUQ, and used System A with less mouse movement, commission errors, and keystrokes than the other PHRs. 相似文献
The exponential increase of subjective, user-generated content since the birth of the Social Web, has led to the necessity of developing automatic text processing systems able to extract, process and present relevant knowledge. In this paper, we tackle the Opinion Retrieval, Mining and Summarization task, by proposing a unified framework, composed of three crucial components (information retrieval, opinion mining and text summarization) that allow the retrieval, classification and summarization of subjective information. An extensive analysis is conducted, where different configurations of the framework are suggested and analyzed, in order to determine which is the best one, and under which conditions. The evaluation carried out and the results obtained show the appropriateness of the individual components, as well as the framework as a whole. By achieving an improvement over 10% compared to the state-of-the-art approaches in the context of blogs, we can conclude that subjective text can be efficiently dealt with by means of our proposed framework. 相似文献
The use of vertical chute marine evacuation systems (MES) is now well established on board marine passenger vessels; this system has yet to be deployed in an emergency situation, however, it has been associated with a fatality and several major injuries during training. Brunel University's Ethics Committee endorsed an initial retrospective cross sectional study (Harwood and Farrow, 2008) and the present quantitative observational study. Harwood and Farrow (2008) found that the physical, physiological and psychological characteristics of potential evacuees increased the likelihood of injury and adversely affected the reliability of the system.
Purpose
The validation of factors associated with the adverse outcomes recorded by Harwood and Farrow (2008) during vertical chute MES training, and to assess the hypothesis that evacuee's clothing material will affect the efficiency of the system.
Design
Observational data in a marine training establishment providing a triangulation measurement process of evidence from the retrospective study (Harwood and Farrow, 2008). Subjects were three hundred and seventy five representative participants on training courses for evacuation from a ship into inflated life rafts. The main outcome measures were stopping during descent and exiting the chute in an undesirable position.
Results
6.1% stopped momentarily during descent; 20.3% exited the chute in an undesirable position; on entering the raft 7.7% flipped over and 9.1% had their legs tucked up under their bodies. Independent variables including evacuees' clothing material were statistically significantly associated with adverse outcomes. Participants stopping during descent had an RR of 3.03 (95% CI 1.38, 6.64) for exiting the chute in an undesirable position.
Conclusions
This quantitative observational study broadly supported the results obtained from the retrospective cross sectional study (Harwood and Farrow, 2008). Stopping during descent and evacuee clothing increased the likelihood of undesirable outcomes and impacted on the efficiency of the system. 相似文献
Complement pathway proteins are reported to be increased in polycystic ovary syndrome (PCOS) and may be affected by obesity and insulin resistance. To investigate this, a proteomic analysis of the complement system was undertaken, including inhibitory proteins. In this cohort study, plasma was collected from 234 women (137 with PCOS and 97 controls). SOMALogic proteomic analysis was undertaken for the following complement system proteins: C1q, C1r, C2, C3, C3a, iC3b, C3b, C3d, C3adesArg, C4, C4a, C4b, C5, C5a, C5b-6 complex, C8, properdin, factor B, factor D, factor H, factor I, mannose-binding protein C (MBL), complement decay-accelerating factor (DAF) and complement factor H-related protein 5 (CFHR5). The alternative pathway of the complement system was primarily overexpressed in PCOS, with increased C3 (p < 0.05), properdin and factor B (p < 0.01). In addition, inhibition of this pathway was also seen in PCOS, with an increase in CFHR5, factor H and factor I (p < 0.01). Downstream complement factors iC3b and C3d, associated with an enhanced B cell response, and C5a, associated with an inflammatory cytokine release, were increased (p < 0.01). Hyperandrogenemia correlated positively with properdin and iC3b, whilst insulin resistance (HOMA-IR) correlated with iC3b and factor H (p < 0.05) in PCOS. BMI correlated positively with C3d, factor B, factor D, factor I, CFHR5 and C5a (p < 0.05). This comprehensive evaluation of the complement system in PCOS revealed the upregulation of components of the complement system, which appears to be offset by the concurrent upregulation of its inhibitors, with these changes accounted for in part by BMI, hyperandrogenemia and insulin resistance. 相似文献
The ability of human pluripotent stem cells for unlimited proliferation and self-renewal promotes their application in the fields of regenerative medicine. The morphological assessment of growing colonies and cells, as a non-invasive method, allows the best clones for further clinical applications to be safely selected. For this purpose, we analyzed seven morphological parameters of both colonies and cells extracted from the phase-contrast images of human embryonic stem cell line H9, control human induced pluripotent stem cell (hiPSC) line AD3, and hiPSC line HPCASRi002-A (CaSR) in various passages during their growth for 120 h. The morphological phenotype of each colony was classified using a visual analysis and associated with its potential for pluripotency and clonality maintenance, thus defining the colony phenotype as the control parameter. Using the analysis of variance for the morphological parameters of each line, we showed that selected parameters carried information about different cell lines and different phenotypes within each line. We demonstrated that a model of classification of colonies and cells by phenotype, built on the selected parameters as predictors, recognized the phenotype with an accuracy of 70–75%. In addition, we performed a qRT-PCR analysis of eleven pluripotency markers genes. By analyzing the variance of their expression in samples from different lines and with different phenotypes, we identified group-specific sets of genes that could be used as the most informative ones for the separation of the best clones. Our results indicated the fundamental possibility of constructing a morphological portrait of a colony informative for the automatic identification of the phenotype and for linking this portrait to the expression of pluripotency markers. 相似文献
Photoprocesses in 1,4-diazadistyrylbenzene (1) and 1,3-diazadistyrylbenzene derivative (2) diperchlorates in MeCN were studied by absorption, luminescence, and kinetic laser spectroscopies. For compound 1, trans-cis-photoisomerization and intersystem crossing to a triplet state are observed. For compound 2, photoelectrocyclization is suggested. Quantum chemical calculations of diazadistyrylbenzene structures in the ground and excited states were carried out. The schemes for photoreactions were proposed. 相似文献