Spectroscopic Multicomponent Analysis Using Multi-objective Optimization for Variable Selection

The multiple determination tasks of chemical properties are a classical problem in analytical chemistry. The major problem is concerned in to find the best subset of variables that better represents the compounds. These variables are obtained by a spectrophotometer device. This device measures hundreds of correlated variables related with physicocbemical properties and that can be used to estimate the component of interest. The problem is the selection of a subset of informative and uncorrelated variables that help the minimization of prediction error. Classical algorithms select a subset of variables for each compound considered. In this work we propose the use of the SPEA-II （strength Pareto evolutionary algorithm II）. We would like to show that the variable selection algorithm can selected just one subset used for multiple determinations using multiple linear regressions. For the case study is used wheat data obtained by NIR （near-infrared spectroscopy） spectrometry where the objective is the determination of a variable subgroup with information about E protein content （%）, test weight （Kg/HI）, WKT （wheat kernel texture） （%） and farinograph water absorption （%）. The results of traditional techniques of multivariate calibration as the SPA （successive projections algorithm）, PLS （partial least square） and mono-objective genetic algorithm are presents for comparisons. For NIR spectral analysis of protein concentration on wheat, the number of variables selected from 775 spectral variables was reduced for just 10 in the SPEA-II algorithm. The prediction error decreased from 0.2 in the classical methods to 0.09 in proposed approach, a reduction of 37%. The model using variables selected by SPEA-II had better prediction performance than classical algorithms and full-spectrum partial least-squares.     

Flatness-Based Control of a Single Qubit Gate

This work considers the open-loop control problem of steering a two-level quantum system from any initial to any final condition. The model of this system evolves on the state space , having two inputs that correspond to the complex amplitude of a resonant laser field. A symmetry preserving flat output is constructed using a fully geometric construction and quaternion computations. Simulation results of this flatness-based open-loop control are provided.     

Performance bounds in linear control of unstable MIMO systems with pole location constraint

This paper proposes a methodology to compute quadratic performance bounds when the closed loop poles of a discrete-time multivariable control loop are confined to a disk, centred at the origin, and with radius less than one. The underlying philosophy in this constraint is to avoid certain undesirable dynamic features which arise in quadratic optimal designs. An expression for the performance loss due to the pole location constraint is also provided. Using numerical examples, we show that the performance loss is compensated by an improved transient performance, specially visible in the control signals.     

A novel electromyographic signal simulator for muscle contraction studies

Mathematical simulation has been widely used in biomedical and biological sciences. In the case of the surface electromyographic (SEMG) activity, some models have been proposed aiming to study muscle contraction strategies that are used during different tasks and conditions. Most of SEMG simulators are based on energy modulation of a Gaussian noise. This work proposes a novel simulator in which the user-defined parameters are associated with the motor units (MUs) recruitment and their firing rate. Comparison between the mean spectrum of real SEMG signals collected in isometric contraction of the muscle biceps brachii and the mean spectrum obtained from simulated SEMG signals showed a good agreement, pointing the proposed simulator seems to be capable to generate consistent electromyographic signals in time and frequency domains and that can be used in many studies, in particular in the evaluation of automatic methods aimed to detect muscular contraction.     

Avatar mobility in user-created networked virtual worlds: measurements, analysis, and implications

We collected mobility traces of avatars spanning multiple regions in Second Life, a popular user-created virtual world. We analyzed the traces to characterize the dynamics of the avatars’ mobility and behavior, both temporally and spatially. We discuss the implications of our findings on the design of peer-to-peer architecture, interest management, mobility modeling of avatars, server load balancing and zone partitioning, caching, and prefetching for user-created virtual worlds.     

A Genre-Aware Approach to Focused Crawling

Focused crawlers have as their main goal to crawl Web pages that are relevant to a specific topic or user interest, playing an important role for a great variety of applications. In general, they work by trying to find and crawl all kinds of pages deemed as related to an implicitly declared topic. However, users are often not simply interested in any document about a topic, but instead they may want only documents of a given type or genre on that topic to be retrieved. In this article, we describe an approach to focused crawling that exploits not only content-related information but also genre information present in Web pages to guide the crawling process. This approach has been designed to address situations in which the specific topic of interest can be expressed by specifying two sets of terms, the first describing genre aspects of the desired pages and the second related to the subject or content of these pages, thus requiring no training or any kind of preprocessing. The effectiveness, efficiency and scalability of the proposed approach are demonstrated by a set of experiments involving the crawling of pages related to syllabi of computer science courses, job offers in the computer science field and sale offers of computer equipments. These experiments show that focused crawlers constructed according to our genre-aware approach achieve levels of F1 superior to 88%, requiring the analysis of no more than 65% of the visited pages in order to find 90% of the relevant pages. In addition, we experimentally analyze the impact of term selection on our approach and evaluate a proposed strategy for semi-automatic generation of such terms. This analysis shows that a small set of terms selected by an expert or a set of terms specified by a typical user familiar with the topic is usually enough to produce good results and that such a semi-automatic strategy is very effective in supporting the task of selecting the sets of terms required to guide a crawling process.     

New insights into the morphology of Trypanosoma cruzi reservosome

Reservosomes are late endosomes present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and are defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. They have been extensively described in Trypanosoma cruzi epimastigote: are bounded by a membrane unit, present an electron-dense protein matrix with electron-lucent lipid inclusions, being devoid of inner membranes. Here we performed a detailed ultrastructural analysis of these organelles using a variety of electron microscopy techniques, including ultrathin sectioning, uranyl acetate stained preparations, and freeze fracture, either in intact epimastigotes or in isolated reservosomes. New informations were obtained. First, both isolated and in situ reservosomes presented small profiles of inner membranes that are morphologically similar to the membrane surrounding the organelle. In uranyl acetate stained preparations, internal membrane profiles turned out to be longer than they appeared in ultrathin section images and traversed the organelle diameter. Internal vesicles were also found. Second, endocytosed cargo are not associated with internal vesicles and reach reservosomes on board of vesicles that fuse with the boundary membrane, delivering cargo directly into reservosome lumen. Third, electron-lucent bodies with saturated lipid core surrounded by a membrane monolayer and with unusual rectangular shape were also observed. Fourth, it was possible to demonstrate the presence of intramembranous particles on the E face of both internal vesicles and the surrounding membrane. Collectively, these results indicate that reservosomes have a complex internal structure, which may correlate with their multiple functions.     

Simple tests for multi-criteria optimality

In this paper we present two tests which can decide whether a given pointx ₀ ^N is locally efficient or not with respect to a given finite set of real valued continuously differentiable functions defined on ^N . Examples indicate that the tests may fail on a nowhere dense set.     

Developed profile of holographically exposed photoresist gratings

A simulation of the profile of holographically recorded structures in photoresists is performed. In addition to its simplicity this simulation can be used to take into account the effects that arise from exposure, photosensitization, development, and resolution of positive photoresists. We analyzed the effects of isotropy of wet development, nonlinearity of the photoresist response curve, background light, and standing waves produced by reflection at the film-substrate interface by using this simulation, and the results agree with the experimentally recorded profiles.     

Extreme-ultraviolet interferometry at 15.5 nm using multilayer optics

The development of multilayer mirror technology capable of operating in the range of 3-30 nm and the construction of thin membranes with excellent uniformity and strength have made it possible to design and implement a Mach-Zehnder interferometer operating at 15.5 nm. We have tested this interferometer by using a soft x-ray laser as a source, and we show its use in probing high-density plasmas.