Analysis of tungsten and titanium migration during ESD contact burnout

A physical and chemical analysis of a machine model (MM) electrostatic discharge (ESD) failure in a silicon circuit was carried out. Focused ion beam (FIB) was used to make cross sections through the region of contact burnout. The resulting samples were analyzed using scanning electron microscopy (SEM) and two-dimensional (2-D) auger electron spectroscopic (AES) mapping. It is shown for the first time that both titanium (Ti) and tungsten (W) migrated throughout the melted silicon filament. Large pellets of the W plug were embedded in the bulk silicon but only on the cathode side of the junction. Mechanisms are discussed to explain these phenomena. These involve the melting of titanium disilicide (TiSi/sub 2/), dissolution of Ti and W in the molten silicon and the formation of W pellets through electromigration at temperatures below /spl sim/1800 K.     

Radon and radon daughter levels in energy efficient housing

radon and radon daughter concentrations have been measured in 33 “energy-efficient” homes in a small subdivision in Kanata, Ontario. Integrated radon measurements were determined over three month periods for a year using solid state nuclear track detectors. Radon and radon daughter grab sample determinations were made during corresponding periods and confirm the distributions of the integrated radon measurements.Annual average individual home radon concentrations show an 8 fold concentration range between homes. This variability in radon concentrations is not reflected in the range of air exchange rates for the homes. A distinct seasonal variation is noted for the median values of the radon and radon daughter concentrations and the equilibrium factor F in the dwellings.     

Quality assessment of SRTM C- and X-band interferometric data: Implications for the retrieval of vegetation canopy height

The Shuttle Radar Topography Mission distinguished itself as the first near-global spaceborne mission to demonstrate direct sensitivity to vertical vegetation structure. Whether this sensitivity is viewed as exploitable signal or unwanted bias, a great deal of interest exists in retrieving vegetation canopy height information from the SRTM data. This study presents a comprehensive application-specific assessment of SRTM data quality, focusing on the characterization and mitigation of two primary sources of relative vertical error: uncompensated Shuttle mast motion and random phase noise. The assessment spans four test sites located in the upper Midwestern United States and examines the dependence of data quality on both frequency, i.e., C-band vs. X-band, and the number of acquired datatakes. The results indicate that the quality of SRTM data may be higher than previously thought. Novel mitigation strategies include a knowledge-based approach to sample averaging, which has the potential to reduce phase noise error by 43 to 80%. The strategies presented here are being implemented as part of an ongoing effort to produce regional- to continental-scale estimates of vegetation canopy height within the conterminous U.S.     

A connectionist implementation of the theory of planned behavior: Association of beliefs with exercise intention.

The theory of planned behavior suggests attitudes are a product of salient beliefs. This study examined whether aggregating salient beliefs was plausible within a more biologically centered information-processing environment. A neural network was used to examine associations among beliefs relating to exercise intention. Data on intentions and behavioral, normative, and control beliefs from 114 respondents were used to train (by error backpropagation) a neural network to associate beliefs with intention. The R2 between the network's estimated and self-reported intention was .66. The network's representation comprised 6 belief profiles associated with high, moderate, or low behavioral intention. The neural network accommodated complex relationships among beliefs and belief-intention associations and indicated how high-level constructs such as attitudes may be viewed as the best fit (compromise state) between aroused beliefs. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Development of composite tissue scaffolds containing naturally sourced mircoporous hydroxyapatite

The aims of this work were to investigate the conversion of a marine alga into hydroxyapatite (HA), and furthermore to design a composite bone tissue engineering scaffold comprising the synthesised HA within a porous bioresorbable polymer. The marine alga, Phymatolithon calcareum, which exhibits a calcium carbonate honeycomb structure, with a natural architecture of interconnecting permeable pores (microporosity 4–11 μm), provided the initial raw material for this study. The objective was to convert the alga into hydroxyapatite while maintaining its porous morphology using a sequential pyrolysis and chemical synthesis processes. Semi-quantitative XRD analysis of the post-hydrothermal material (pyrolised at 700–750 °C), indicated that the calcium phosphate (CaP) ceramic most likely consisted of a calcium carbonate macroporous lattice, with hydroxyapatite crystals on the surface of the macropores. Cell visibility (cytotoxicity) investigations of osteogenic cells were conducted on the CaP ceramic (i.e., the material post-hydrothermal analysis) which was found to be non-cytotoxic and displayed good biocompatibility when seeded with MG63 cells. Furthermore, a hot press scaffold fabrication technique was developed to produce a composite scaffold of CaP (derived from the marine alga) in a polycaprolactone (PCL) matrix. A salt leaching technique was further explored to introduce macroporosity to the structure (50–200 μm). Analysis indicated that the scaffold contained both micro/macroporosity and mechanical strength, considered necessary for bone tissue engineering applications.     

The diastolic debate: is it time to discard Korotkoff phase IV in favour of phase V for blood pressure measurements in pregnancy?

The IgE-mediated allergic response involves a series of physiological pathways that result in the array of symptoms commonly associated with allergy. This article describes the mediators that prompt specific clinical responses and identifies those at risk for latex hypersensitivity.     

Meniscal regeneration in the long-term after total meniscectomy?

A cohort of 39 patients (28 male, 11 female) that had undergone total meniscectomy as adolescents (mean age 16 years) underwent FISP 3D Magnetic Resonance Imaging at a mean follow up of 30 years. The presence of meniscal tissue was assessed by two independent observers blinded to the operation details. The volume of any meniscal tissue present was calculated. A posterior horn remnant was seen in 57% of medial and 45% of lateral meniscectomy cases. The mean volume of an operated medial meniscal remnant was 0.29 mL compared with a mean volume of 1.15 mL for an intact medial meniscus. The mean volume of an operated lateral meniscal remnant was 0.30 mL compared with 1.07 mL for an intact lateral meniscus. We have shown that the incidence of incomplete excision of the posterior horn is more common after total medial meniscectomy, and that at a mean follow up of 30 years there is no convincing in vivo MRI evidence of long-term meniscal regeneration.     

Efficacy of a two-component acellular pertussis vaccine in infants

OBJECTIVE: This case-control study investigated the protective efficacy against pertussis of three doses of a two-component acellular pertussis vaccine (manufactured by Biken in Japan) combined with diphtheria and tetanus toxoids (manufactured by Connaught Laboratories in the US) in infants. METHODS: A case-control study was performed in 63 pediatric practices in Germany. Prospective recruitment of 16,780 infants ages 6 to 17 weeks took place between February, 1993, and July, 1994. According to parental choice infants received either Biken acellular pertussis vaccine combined with diphtheria and tetanus toxoids (DTacP) (74.6%) at approximately 2, 4 and 6 months of age, or a licensed German diphtheria-tetanus toxoids-whole cell pertussis vaccine (10.9%), diphtheria-tetanus toxoids vaccine (12.5%) or no vaccine (2.0%). Prospective surveillance of pertussis cases between February, 1993, and May, 1995, was accomplished by culturing all infants < or =2 years of age presenting with cough > or = 7 days. A pertussis case was defined as any cough of 21 days or longer plus a positive Bordetella pertussis culture or household contact exposure. RESULTS: We identified 241 pertussis cases prospectively by 11,017 B. pertussis cultures and 949 controls matched for age were selected from the same pediatric practices. Medical history and demographic and vaccine status data were collected from each case and for four controls. Data were analyzed through conditional logistic regression taking into account individual matching and adjusting for potential confounding variables. DTacP combined with diphtheria and tetanus toxoids vaccine was 82% protective (95% confidence interval, 68 to 90), diphtheria-tetanus toxoids-whole cell pertussis vaccine was 96% protective (95% confidence interval, 78 to 99). Protection against typical B. pertussis infection characterized by paroxysmal cough lasting > or =21 days was 96% (95% confidence interval, 87 to 99) for DTacP and was 97% (95% confidence interval, 79 to 100) for diphtheria-tetanus toxoids-whole cell pertussis vaccine. Adjustment for potentially confounding variables did not change the results significantly. CONCLUSIONS: Three doses of the two-component acellular pertussis vaccine protected infants against pertussis disease during the period before the recommended booster vaccination. For typical pertussis disease as defined by the WHO efficacy was high and similar to that of a licensed German diphtheria-tetanus toxoids-whole cell pertussis vaccine.     

Failure mode analysis for a hazardous waste clean-up manipulator

This paper describes the application of Fault Tree Analysis to the design phase of a robot manipulator for hazardous waste retrieval. The robot is to be deployed in single-shell under-ground storage tanks at the US Department of Energy (DOE) site in Hanford, Washington. These tanks contain a variety of highly radioactive waste types, necessitating extremely safe and reliable manipulator operation. Based on preliminary design drawings of this long-reach manipulator, fault trees were constructed for several critical failure scenarios. Analysis of the trees revealed a number of ways to improve the safety and reliability of the manipulator design. This paper presents a summary of the fault tree analysis, with a discussion of the applicability of qualitative and quantitative fault tree methods to hazardous waste robotics.     

An empirical InSAR-optical fusion approach to mapping vegetation canopy height

Exploiting synergies afforded by a host of recently available national-scale data sets derived from interferometric synthetic aperture radar (InSAR) and passive optical remote sensing, this paper describes the development of a novel empirical approach for the provision of regional- to continental-scale estimates of vegetation canopy height. Supported by data from the 2000 Shuttle Radar Topography Mission (SRTM), the National Elevation Dataset (NED), the LANDFIRE project, and the National Land Cover Database (NLCD) 2001, this paper describes a data fusion and modeling strategy for developing the first-ever high-resolution map of canopy height for the conterminous U.S. The approach was tested as part of a prototype study spanning some 62,000 km² in central Utah (NLCD mapping zone 16). A mapping strategy based on object-oriented image analysis and tree-based regression techniques is employed. Empirical model development is driven by a database of height metrics obtained from an extensive field plot network administered by the USDA Forest Service-Forest Inventory and Analysis (FIA) program. Based on data from 508 FIA field plots, an average absolute height error of 2.1 m (r = 0.88) was achieved for the prototype mapping zone.