全文获取类型
收费全文 | 173152篇 |
免费 | 26505篇 |
国内免费 | 6121篇 |
专业分类
电工技术 | 9973篇 |
技术理论 | 5篇 |
综合类 | 9272篇 |
化学工业 | 41683篇 |
金属工艺 | 7527篇 |
机械仪表 | 8555篇 |
建筑科学 | 11544篇 |
矿业工程 | 3278篇 |
能源动力 | 4551篇 |
轻工业 | 17854篇 |
水利工程 | 2911篇 |
石油天然气 | 5452篇 |
武器工业 | 962篇 |
无线电 | 22328篇 |
一般工业技术 | 28085篇 |
冶金工业 | 6760篇 |
原子能技术 | 1499篇 |
自动化技术 | 23539篇 |
出版年
2024年 | 439篇 |
2023年 | 2415篇 |
2022年 | 3647篇 |
2021年 | 5756篇 |
2020年 | 5414篇 |
2019年 | 6346篇 |
2018年 | 6494篇 |
2017年 | 7199篇 |
2016年 | 7333篇 |
2015年 | 8898篇 |
2014年 | 10290篇 |
2013年 | 13375篇 |
2012年 | 11218篇 |
2011年 | 11490篇 |
2010年 | 10962篇 |
2009年 | 10584篇 |
2008年 | 9712篇 |
2007年 | 9160篇 |
2006年 | 8734篇 |
2005年 | 7299篇 |
2004年 | 5498篇 |
2003年 | 5234篇 |
2002年 | 5597篇 |
2001年 | 4841篇 |
2000年 | 3999篇 |
1999年 | 3254篇 |
1998年 | 2554篇 |
1997年 | 2154篇 |
1996年 | 1954篇 |
1995年 | 1685篇 |
1994年 | 1339篇 |
1993年 | 1152篇 |
1992年 | 918篇 |
1991年 | 725篇 |
1990年 | 627篇 |
1989年 | 541篇 |
1988年 | 442篇 |
1987年 | 374篇 |
1986年 | 362篇 |
1985年 | 320篇 |
1984年 | 269篇 |
1983年 | 249篇 |
1982年 | 233篇 |
1981年 | 270篇 |
1980年 | 240篇 |
1979年 | 212篇 |
1975年 | 219篇 |
1974年 | 208篇 |
1973年 | 389篇 |
1972年 | 220篇 |
排序方式: 共有10000条查询结果,搜索用时 203 毫秒
81.
林殿芳 《山东电力高等专科学校学报》2015,(1):66-69
文章首先对暑期学校的发展历史和现状进行了分析,指出了现阶段国内高校暑期学校发展中的问题和瓶颈。针对提出的问题,文章剖析了开设暑期学校的理论支撑和实践基础,并结合山东大学九年办学实践经验说明暑期学校在深化教学改革、创新人才培养模式、提高教学质量和办学水平、扩大学校影响力,全面提升学校国际化的积极作用。 相似文献
82.
樊琳 《石油化工安全环保技术》2020,(2):1-3,I0001
分包商安全能力不足以及总包商安全管理薄弱,已成为导致工程建设项目事故多发的重要原因。将分包商的安全管理有效纳入到总承包商的安全管理体系内,做好分包商的安全管理,对提高总承包商的安全绩效、确保施工安全,具有极其重要的现实意义。从总承包商和分包商两个角度,研究分析分包安全管理中存在的问题及原因,得出分包安全管理各种问题的根源主要是经济利益,管理源头在总承包单位,站在总承包商的视角提出加强分包商安全管理的建议。 相似文献
83.
Yong Xu Yun Li Songlin Li Francis Balestra Gerard Ghibaudo Wenwu Li Yen‐Fu Lin Huabin Sun Jing Wan Xinran Wang Yufeng Guo Yi Shi Yong‐Young Noh 《Advanced functional materials》2020,30(20)
Unreliable mobility values, and particularly greatly overestimated values and severely distorted temperature dependences, have recently hampered the development of the organic transistor field. Given that organic field‐effect transistors (OFETs) have been routinely used to evaluate mobility, precise parameter extraction using the electrical properties of OFETs is thus of primary importance. This review examines the origins of the various mobilities that must be determined for OFET applications, the relevant extraction methods, and the data selection limitations, which help in avoiding conceptual errors during mobility extraction. For increased precision, the review also discusses device fabrication considerations, calibration of both the specific gate‐dielectric capacitance and the threshold voltage, the contact effects, and the bias and temperature dependences, which must actually be handled with great care but have mostly been overlooked to date. This review serves as a systematic overview of the OFET mobility extraction process to ensure high precision and will also aid in improving future research. 相似文献
84.
Sebastian Roth Peter Stockinger Jakob Steff Simon Steimle Dr. Viktor Sautner Prof. Dr. Kai Tittmann Prof. Dr. Jürgen Pleiss Prof. Dr. Michael Müller 《Chembiochem : a European journal of chemical biology》2020,21(18):2615-2619
The family of NAD(P)H-dependent short-chain dehydrogenases/reductases (SDRs) comprises numerous biocatalysts capable of C=O or C=C reduction. The highly homologous noroxomaritidine reductase (NR) from Narcissus sp. aff. pseudonarcissus and Zt_SDR from Zephyranthes treatiae, however, are SDRs with an extended imine substrate scope. Comparison with a similar SDR from Asparagus officinalis (Ao_SDR) exhibiting keto-reducing activity, yet negligible imine-reducing capability, and mining the Short-Chain Dehydrogenase/Reductase Engineering Database indicated that NR and Zt_SDR possess a unique active-site composition among SDRs. Adapting the active site of Ao_SDR accordingly improved its imine-reducing capability. By applying the same strategy, an unrelated SDR from Methylobacterium sp. 77 (M77_SDR) with distinct keto-reducing activity was engineered into a promiscuous enzyme with imine-reducing activity, thereby confirming that the ability to reduce imines can be rationally introduced into members of the “classical” SDR enzyme family. Thus, members of the SDR family could be a promising starting point for protein approaches to generate new imine-reducing enzymes. 相似文献
85.
Yu-Jiao Liu Xiao-Yang Fan Dr. Dong-Dong Zhang Yin-Zheng Xia Dr. Yan-Jun Hu Feng-Lei Jiang Prof. Fu-Ling Zhou Prof. Yi Liu 《ChemMedChem》2020,15(6):552-558
Based on the potential therapeutic value in targeting mitochondria and the fluorophore tracing ability, a fluorescent mitochondria-targeted organic arsenical PDT-PAO-F16 was fabricated, which not only visualized the cellular distribution, but also exerted anti-cancer activity in vitro and in vivo via targeting pyruvate dehydrogenase complex (PDHC) and respiratory chain complexes in mitochondria. In details, PDT-PAO-F16 mainly accumulated into mitochondria within hours and suppressed the activity of PDHC resulting in the inhibition of ATP synthesis and thermogenesis disorder. Moreover, the suppression of respiratory chain complex I and IV accelerated the mitochondrial dysfunction leading to caspase family-dependent apoptosis. In vivo, the acute promyelocytic leukemia was greatly alleviated in the PDT-PAO-F16 treated group in APL mice model. Our results demonstrated the organic arsenical precursor with fluorescence imaging and target-anticancer efficacy is a promising anticancer drug. 相似文献
86.
Cerebral microbleeds and cognitive decline in a hemodialysis patient: Case report and review of literature 下载免费PDF全文
Lin Li Mark Fisher Wei‐Ling Lau Hamid Moradi Alexander Cheung Gaby Thai Jason Handwerker Kamyar Kalantar‐Zadeh 《Hemodialysis international. International Symposium on Home Hemodialysis》2015,19(3):E1-E7
Cerebral microbleeds (CMBs) are small hemosiderin deposits indicative of prior cerebral microscopic hemorrhage and previously thought to be clinically silent. Recent population‐based cross‐sectional studies and prospective longitudinal cohort studies have revealed association between CMB and cognitive dysfunction. In the general population, CMBs are associated with age, hypertension, and cerebral amyloid angiopathy. In the chronic kidney disease (CKD) population, diminished estimated glomerular filtration rate has been found to be an independent risk factor for CMB, raising the possibility that a uremic milieu may predispose to microbleeds. In the end‐stage renal disease (ESRD) population on hemodialysis, the incidence of microbleeds is significantly higher compared with a control group without history of CKD or stroke. We present an ESRD patient on chronic hemodialysis with a history of gradual cognitive decline and progressive CMBs. Through this case and literature review, we illustrate the need to develop detection and prediction models to treat this frequent development in ESRD patients. 相似文献
87.
Adaptive backstepping repetitive learning control design for nonlinear discrete‐time systems with periodic uncertainties 下载免费PDF全文
Qiao Zhu Jian‐Xin Xu Shiping Yang Guang‐Da Hu 《International Journal of Adaptive Control and Signal Processing》2015,29(4):524-535
This paper addresses a tracking problem for uncertain nonlinear discrete‐time systems in which the uncertainties, including parametric uncertainty and external disturbance, are periodic with known periodicity. Repetitive learning control (RLC) is an effective tool to deal with periodic unknown components. By using the backstepping procedures, an adaptive RLC law with periodic parameter estimation is designed. The overparameterization problem is overcome by postponing the parameter estimation to the last backstepping step, which could not be easily solved in robust adaptive control. It is shown that the proposed adaptive RLC law without overparameterization can guarantee the perfect tracking and boundedness of the states of the whole closed‐loop systems in presence of periodic uncertainties. In addition, the effectiveness of the developed controller is demonstrated by an implementation example on a single‐link flexible‐joint robot. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
88.
89.
Wan‐Xia Wu 《Polymer International》2019,68(11):1848-1855
A series of novel aliphatic poly(β‐thioether ester)s with various methylene group contents were prepared by direct lipase‐catalyzed polycondensation of the monomer with an acid‐labile β‐thiopropionate group. The polycondensation reaction using immobilized lipase B from Candida antarctica was carried out in diphenyl ether at 90 °C. Poly(β‐thioether ester)s with high molecular weights of 20 500–57 000 Da and narrow polydispersities in the range 1.40–1.48 were obtained. Thermogravimetric analysis, differential scanning calorimetry and wide‐angle X‐ray diffraction were used to investigate the thermal properties and crystal structures of these polyesters. All the poly(β‐thioether ester)s were semicrystalline polymers and thermally stable up to at least 200 °C. In vitro degradation studies showed that they can rapidly degrade under acidic conditions by the hydrolysis of the β‐thiopropionate groups, suggesting their potential as acid‐degradable polymeric materials. © 2019 Society of Chemical Industry 相似文献
90.
Dr. Kathrin Schindl Dr. Deepika Sharma Prof. Dr. Dieter Spiteller 《Chembiochem : a European journal of chemical biology》2020,21(21):3151-3157
When Streptomyces violaceoruber grows together with Streptomyces sp. MG7-G1, it reacts with strongly induced droplet production on its aerial mycelium. Initially the metabolite profile of droplets from S. violaceoruber in co-culture with Streptomyces sp. MG7-G1 was compared to samples from S. violaceoruber in single-culture by using high-performance liquid chromatography-mass spectrometry (HPLC-MS). Then, the exudate from agar plates of co-cultures and single cultures (after freezing and thawing) was also analysed. Several compounds were only observed when S. violaceoruber was grown in co-culture. Based on their high-resolution ESI mass spectra and their comparable retention times to the calcium-dependent antibiotics (CDAs) produced by S. violaceoruber, the new compounds were suspected to be deacylated calcium-dependent antibiotics (daCDAs), lacking the 2,3-epoxyhexanoyl residue of CDAs. This was verified by detailed analysis of the MS/MS spectra of the daCDAs in comparison to the CDAs. The major CDA compounds present in calcium ion-supplemented agar medium of co-cultures were daCDAs, thus suggesting that Streptomyces sp. MG7-G1 expresses a deacylase that degrades CDAs. 相似文献