Acanthopanax senticosus Polysaccharide Enhances the Pathogen Resistance of Radiation-Damaged Caenorhabditis elegans through Intestinal p38 MAPK-SKN-1/ATF-7 Pathway and Stress Response

With the advancement of science and technology, humans are chronically exposed to ionizing radiation. It is crucial to look for efficient and low-toxic anti-radiation agents. Through preliminary screening, we found that Acanthopanax senticosus polysaccharide (ASPS) played a major role in regulating immune damage caused by radiation. The objective of this study was to apply the Caenorhabditis elegans—P. aeruginosa (PA14) infection model to illuminate the mechanism of ASPS increasing the pathogen resistance of radiation-damaged nematodes. Results indicated that ASPS (1 mg/mL) significantly enhanced the pathogen resistance of radiation-damaged nematodes by directly elevating the immune response of nematodes rather than by affecting the bacterial activity. Through further research on the p38 MAPK signaling pathway and related mutants, we found that ASPS functioned by the p38 MAPK pathway in the intestine, and SKN-1, ATF-7 as the downstream targets of PMK-1 participated the regulation of ASPS. In addition, ASPS markedly alleviated the stress status of damaged nematodes by regulating oxidative stress. Collectively, our findings suggest that ASPS enhances the pathogen resistance of radiation-damaged nematodes through the intestinal p38MAPK-SKN-1/ATF-7 pathway and stress response.     

基于熵相关系数的关联性自动判别方法——COCA

数据库自管理、自调优中查询计划的自动优化是目前的关注热点。为保证优化器估值精度,用统计学方法,给出了一种基于熵相关系数的对字段关联性的自动判别的新算法——COCA。该算法有下列特点：（1）限制少,没有卡方检验的频数限制,卡方检验只有在列联表中至少有80%的格子频数大于5的情况下才可信; （2）结果多,卡方检验（CORDS）只判断字段之间是否有关联,新方法可计算字段之间双向的关联程度。实验表明, 新方法更坚固,产生更多的统计信息,可以支持后面更高效、准确地建立直方图。     

Shaping the interdisciplinary knowledge network of China: a network analysis based on citation data from 1981 to 2010

This study builds the interdisciplinary knowledge network of China, which is used to catch the knowledge exchange structure of disciplines, and investigates the evolution process from 1981 to 2010. A network analysis was performed to examine the special structure and we compare state of the networks in different periods to determine how the network has got such properties. The dataset are get from the reference relationship in literature on important Chinese academic journals from 1980 to 2010. The analytical results reveal the hidden network structure of interdisciplinary knowledge flows in China and demonstrate that the network is highly connected and has a homogeneous link structure and heterogeneous weight distribution. Through comparing of the network in three periods, that is 1981–1990, 1991–2000 and 2001–2010, we find that the special evolution process, which is limited by the number of nodes, play an important influence on interdisciplinary knowledge flows.     

温敏型有机-无机杂化纳米微胶囊的渗透性能

将N-异丙基丙烯酰胺引入以正十六烷为模板的苯乙烯与甲基丙烯酸-3-三甲氧基硅丙酯细乳液共聚法制备纳米微胶囊的体系,得到一种温敏型有机-无机杂化纳米微胶囊。采用紫外可见分光光度计研究该种微胶囊在临界温度附近对甲酚红的载入和释放行为。结果表明N-异丙基丙烯酰胺的引入和温度均影响纳米微胶囊对甲酚红的载入与释放。微胶囊在临界温度以上具有一定渗透速率,临界温度以下渗透不明显,能较好地实现开-关式环境温敏型控制吸附和释放。     

一种多相插值滤波器的设计与应用

为了满足某高速卫星通信地球站调制解调器对多相插值滤波器的实际应用设计需要,分析了多相插值滤波器的一般设计原理,给出了一种多相插值滤波器的设计方法。采用VHDL语言TOP—DOWN设计方法,用XILINX VIRTEX-xv600系列FPGA进行了实现,对FPGA设计进行了仿真与测试。给出了部分仿真、实际应用测试结果。证明了设计的多相插值滤波器的正确性与可行性。     

计及旁路二极管效应的太阳能模组性能评估

为避免功率失配损失,太阳能模组一般都配置旁路二极管,提供一个能量散逸的途径。基于这种配置提出一种新的太阳能模组性能评估算法。依据实际旁路区段配置建立网络方程,通过牛顿–拉夫逊非线性迭代方法实现拓扑求解,继而获得模组的整体性能。在用制造商标准测试数据验证了该评估算法的有效性后,进一步考察各种阴影场景下的模组整体性能,并给出全局最大功率点(maximal power point,MPP)位置随辐射强度变化时的定性结论。理论分析和仿真结果表明,由于多辐射强度导致功率多峰值的存在,常规最大功率点跟踪(maximal power point track,MPPT)算法可能会因为只能检测到MPPT伪极大值点而失效;而且,旁路二极管的合理配置对太阳能模组性能有很大影响。     

关于开关检修工作中二次回路隔离的探讨

开关检修是变电站常见的工作之一,但是运行人员对其二次回路隔离的理解、执行多不完全,给检修工作造成了安全隐患。文章在分析开关检修工作二次回路隔离的基础上。结合调度规程、现场规程等提出了二次回路隔离具体可行的操作方案,以保证开关检修过程中的人身安全、设备安全。     

热处理过程中Hg1—xCdxTe／CdTe界面互扩散研究

对ＨｇＣｄＴｅ／ＣｄＴｅ／ＧａＡｓ结构热处理后的样品进行深度剥层腐蚀,并用椭偏光谱测量方法,获得了样品在４９０℃经０．５ｈ和２ｈ热处理后不同深度下的组份分布．根据实验结果对Ｚａｎｉｏ等人提出的扩散系数公式进行了修正,得到４９０℃热处理条件下的组份扩散系数ＤＨｇ１－ｘＣｄｘＴｅ（４９０℃）＝４×１０－３×１０－３·ｘ．     

Transition‐Metal Dichalcogenide NiTe2: An Ambient‐Stable Material for Catalysis and Nanoelectronics

By means of theory and experiments, the application capability of nickel ditelluride (NiTe₂) transition‐metal dichalcogenide in catalysis and nanoelectronics is assessed. The Te surface termination forms a TeO₂ skin in an oxygen environment. In ambient atmosphere, passivation is achieved in less than 30 min with the TeO₂ skin having a thickness of about 7 Å. NiTe₂ shows outstanding tolerance to CO exposure and stability in water environment, with subsequent good performance in both hydrogen and oxygen evolution reactions. NiTe₂‐based devices consistently demonstrate superb ambient stability over a timescale as long as one month. Specifically, NiTe₂ has been implemented in a device that exhibits both superior performance and environmental stability at frequencies above 40 GHz, with possible applications as a receiver beyond the cutoff frequency of a nanotransistor.     

阵列波导光栅解复用器的偏振相关损耗的优化

对硅基二氧化硅阵列波导光栅解复用器(AWG DEMUX)的偏振相关损耗(PDL)进行了优化。理论分析了引起AWG偏振相关性的物理因素以及消除偏振相关性的工艺方法和条件。利用化学气相沉积、光刻和刻蚀等半导体工艺制备了AWG DEMUX芯片,并结合理论分析对包层材料中的硼(B)、磷(P)含量进行了优化调整,成功地将芯片的PDL降低至0.12 dB,使PDL参数满足芯片的商用化需求。