An antinociceptive effect of the intraperitoneal injection of nifedipine in rats, measured by tail-flick test

The tail-flick (TF) technique was used to assess the antinociceptive properties of nifedipine (NIF) given intraperitoneally (i.p.). First, the most suitable intensity of the noxious stimulus (temperature of the bulb) has been ascertained and used in the main study. Male Sprague-Dawley rats received NIF, dissolved in dimethyl sulfoxide (DMSO) at the doses of 0.0, 0.5, 2, 5, 10 and 15 mg/kg, or control with no injection. For the main study, the noxious stimulus was limited to 15 sec (cut-off time) and TF latencies were recorded up to 120 min. The antinociceptive response was expressed as the area under the curve for each rat and analyzed by one-way ANOVA. The antinociceptive response to the lower doses of NIF (0.5 and 2 mg/kg) did not differ from control (no injection) and DMSO alone. Significance was found at 5, 10 and 15 mg NIF with no difference among the doses. However, there was an increasing tendency of the mean values from 0.5 to 15 mg NIF resulting in a positive correlation. The correlation coefficient was 0.32483 (p = 0.015) and regression equation Y = (19.37) x dose + 1320. Our data suggest that spinal mechanisms are involved in NIF-induced antinociception.     

An extraction method to determine interconnect parasitic parameters

Interconnect parasitic parameters in integrated circuits have significant impact on circuit speed. An accurate monitoring of these parameters can help to improve interconnect performance during process development, provide information for circuit design, or give useful reference for circuit failure analysis. Existing extraction methods either are destructive (such as SEM measurement) or can determine only partial parasitic parameters (such as large capacitor measurement). In this paper, we present a new method for extracting interconnect parasitic parameters, which can simultaneously determine the interlayer and intralayer capacitances, line resistance, and effective line width. The method is based on two test patterns of the same structure with different dimensions. The structure consumes less wafer area than existing methods. The method shows good agreement with SEM measurement of dielectric thickness in both nonglobal planarized and chemical-mechanical polished processes, and gives accurate prediction of the process spread of a ring oscillator speed over a wafer     

Theory of soliton stability in asynchronous modelocking

A new type of fiber laser modelocking is examined where a phase modulator is driven asynchronously with respect to a harmonic of the roundtrip cavity frequency. An asynchronous drive is able to produce high repetition rate (>1 GHz) soliton pulses that are shorter than the classic, active modelocking pulse width limit. It is shown that with a proper choice of fiber parameters, noise cleanup and soliton pulse shaping can be obtained using filtering and asynchronous phase modulation. Limits of asynchronous detuning are derived and a comparison with the parameters ranges for synchronous phase modulation is also presented     

High-speed milling of titanium alloys using binderless CBN tools

The performance of conventional tools is poor when used to machine titanium alloys. In this paper, a new tool material, which is binderless cubic boron nitride (BCBN), is used for high-speed milling of a widely used titanium alloy Ti–6Al–4V. The performance and the wear mechanism of the BCBN tool have been investigated when slot milling the titanium alloy in terms of cutting forces, tool life and wear mechanism. This type of tool manifests longer tool life at high cutting speeds. Observations based on the SEM and EDX suggest that adhesion of workpiece and attrition are the main wear mechanisms of the BCBN tool when used in high-speed milling of Ti–6Al–4V.     

Fluor SOx净化工艺--为俄罗斯绿色环境开发的将SO2转化为元素硫的经济技术

Fluor公司开发的Fluor SO_2净化工艺具有广泛多样的工艺布局,可以通过经济的方式定制脱除烟气中的有害组成。该工艺几乎能去除全部SO_2并减少CO排放。Fluor SO_x净化工艺的主要步骤已在多套工业装置中得到成功的证实。除技术可行、经济合理之外,Fluor SO_x净化工艺不会产生任何有害副产物,也不会遇到与SO_3 有关的腐蚀问题。此外,该工艺生产高纯度可市售的元素硫。论述了Fluor SO_x净化工艺的特征、技术和成本优势、设计和操作的简易性以及实施的便利性。     

Diterpene resin acids: Major active principles in tall oil against Variegated cutworm,Peridroma saucia (Lepidoptera: Noctuidae)

Tall oil, a by-product of the kraft process for pulping softwood, has been shown to have insecticidal properties. In the present study, the active principles in tall oil against the variegated cutworm,Peridroma saucia Hübner, were investigated. GC-MS analysis showed that abietic, dehydroabietic, and isopimaric acids were major resin acid components of crude tall oil and depitched tall oil. When crude tall oil samples of differing resin acid composition were incorporated into artificial diet at a concentration of 2.0% fresh weight, they suppressed larval growth by 45–60% compared to controls. This suppression was significantly (P0.05) correlated with the equivalent contents of abietic, dehydroabietic, isopimaric, and total resin acids. These results were also evident from a diet choice test, showing that the second-instar larvae obviously selected diets with low levels of resin acids when different diets were randomly arranged in a Petri dish. Bioassays with pure resin acids (abietic, dehydroabietic, and isopimaric acids) demonstrated that all individual chemicals have similar bioactivity against this insect. Comparison of the bioactivities of depitched tall oil and an equivalent mixture of pure resin acids in thePeridroma chronic growth bioassay indicated that pure resin acids and depitched tall oil share a common mode of action to this insect. This study confirms that resin acids are major active principles in tall oil against the variegated cutworm, but other chemicals likely also contribute to the bioactivity of tall oil.     

Evaluating Social Navigation Visualization in Online Geographic Maps

Social navigation enables emergent collaboration between independent collaborators by exposing the behavior of each individual. This is a powerful idea for web-based visualization, where the work of one user can inform other users interacting with the same visualization. Results from a crowdsourced user study evaluating the value of such social navigation cues for a geographic map service are presented. Results show significantly improved performance for participants who interacted with the map when the visual footprints of previous users were visible.     

Perceptual image preview

Image preview is a convenient way to browse large or multiple images on small displays. However, current signal-level image resampling algorithms may remove many features of interest in the preview image. In this paper, we propose perceptual image preview which retains more perceptual features such that users can inspect features of interest by viewing the preview image only and without zooming in. This technology has two components, structure enhancement and perceptual feature visualization. Structure enhancement enhances the image structure while suppressing subtle details using a gradient modulation method, thus making the succedent perceptual features more apparent. For perceptual feature visualization, features of interest detected in the picture is visualized on the structure enhanced preview image. We demonstrate with two examples of most commonly used image quality features, image blur and noise. The effectiveness of the proposed method is validated by experimental results.     

Space-variant optical logic operations based on operation-dependent encoding method

We propose performing space-variant optical logic operations in a space-invariant optical system by selectively assigning encoding states that are operation dependent. With this method, encoders using liquid-crystal cells and liquid-crystal light valves to perform space-variant encoding for all 16 Boolean functions are designed. Multiple-instruction-multiple-data processing can then be realized in optical logic systems.