The (R)evolution of access networks for the informationsuperhighway

Competition in deregulated telecommunication markets forces network operators to modernize their access networks-often called the “last mile” to the customer-to provide a mix of multimedia and traditional telecommunication services. Economics necessitate an evolutionary, step-by-step approach to migrate from the present access infrastructure-composed mainly of existing telephone networks and cable TV networks-to the ultimate information superhighway. At the end of the day, however, networks of different operators should provide interconnectivity for the same set of services. A system concept is described that drives access network technology toward a “common platform” with generic access methods, cognate routing and switching, and common, standardized communication protocols. Simulation results show some performance figures of the common platform concept. An implementation on a CATV network is presented as well     

Cost-sensitive ensemble learning: a unifying framework

Data Mining and Knowledge Discovery - Over the years, a plethora of cost-sensitive methods have been proposed for learning on data when different types of misclassification errors incur different...     

Control of Polymorph Selection in Amorphous Calcium Carbonate Crystallization by Poly(Aspartic Acid): Two Different Mechanisms

Poly(aspartic acid) (pAsp) is known to stabilize amorphous calcium carbonate (ACC) and affect its crystallization pathways. However, little is known about the mechanisms behind these phenomena. Here it is shown that ACC is stabilized by pAsp molecules in the solution rather than by the amount of pAsp incorporated into the ACC bulk, and that the effect of pAsp on the polymorph selection is entirely different at low and high concentration of pAsp. At low concentrations, pAsp is more effective in inhibiting the nucleation and growth of vaterite than calcite. At high concentrations, when calcite formation is prevented, the crystallization of vaterite proceeds via a pseudomorphic transformation of ACC nanospheres, where vaterite nucleates on the surface of ACC nanospheres and grows by a local transformation of the bulk ACC phase. These results shed some light on the function of pAsp during an ACC‐mediated biomineralization process and provide an explanation for the presence of metastable vaterite at conditions where calcite is thermodynamically favored.     

Preparation of Zinc Titanate Thin Films by Low-Pressure Metalorganic Chemical Vapor Deposition

Homogeneous thin films of zinc titanate have been successfully prepared on Si(100) wafers by depositing a film of zinc and titanium oxides (ZnO-TiO₂) by low-pressure metalorganic chemical vapor deposition (MOCVD), followed by an annealing treatment. The precursors used for the deposition were diethylzinc (DEZ), tetraisopropoxide titanium (TPT), and water. By performing the deposition at temperatures between 140 and 350C, the stoichiometry of the as-deposited films could be effectively controlled over Zn/Ti ratios between 0.5 and 2.5, which cover the composition of various zinc titanate phases identified in the literature. The as-deposited ZnO-TiO₂ films are amorphous, and possess a fairly smooth surface. XPS and SIMS analysis showed that the composition of these films is uniform over the wafer as well as through the films bulk. An annealing treatment of the as-deposited films at high temperature     

Change patterns

Change, such as in the requirements or the assumptions of a system, has a far-reaching impact across several software artifacts. This paper argues that patterns of co-evolution (or change patterns) can be observed between intertwined pairs of artifacts, like the requirements specification and the architectural design. The paper introduces change patterns as a precise framework to systematically capture and handle change. The approach is based on model-driven engineering concepts and is accompanied by a tool-supported process. Changing trust assumptions are presented as an example of security-related evolution, and are used to illustrate the approach. The approach is empirically validated by means of a controlled experiment involving 12 subjects, and a case study involving an industrial partner.     

Leaving the third dimension: no measurable evidence for cognitive aftereffects of stereoscopic 3D movies

Stereoscopic 3D (S‐3D) is becoming an increasingly important display technology. Parallel to this, concern about the potential negative effects of exposure to S‐3D movies has been growing. Some manufacturers place disclaimers on their TVs advising people to limit the time they watch S‐3D. However, surprisingly little experimental research has been conducted estimating the genuineness of these concerns. Therefore, an experiment was designed to assess the potential impact of viewing an S‐3D movie on visual, spatial, and general attention performance. To mimic the real‐world experience of watching a movie in the living room, participants (N = 61) watched a full movie in either 2D or S‐3D. Our results do not show evidence for cognitive aftereffects of S‐3D movies. A second experiment (N = 32) that focused on possible aftereffects on visual attention also failed to find reliable effects. We therefore conclude that cognitive functioning is not altered by watching an S‐3D movie, at least not to an extent that is measurable through well‐established cognitive tasks.     

Identification and Validation of Esophageal Squamous Cell Carcinoma Targets for Fluorescence Molecular Endoscopy

Dysplasia and intramucosal esophageal squamous cell carcinoma (ESCC) frequently go unnoticed with white-light endoscopy and, therefore, progress to invasive tumors. If suitable targets are available, fluorescence molecular endoscopy might be promising to improve early detection. Microarray expression data of patient-derived normal esophagus (n = 120) and ESCC samples (n = 118) were analyzed by functional genomic mRNA (FGmRNA) profiling to predict target upregulation on protein levels. The predicted top 60 upregulated genes were prioritized based on literature and immunohistochemistry (IHC) validation to select the most promising targets for fluorescent imaging. By IHC, GLUT1 showed significantly higher expression in ESCC tissue (30 patients) compared to the normal esophagus adjacent to the tumor (27 patients) (p < 0.001). Ex vivo imaging of GLUT1 with the 2-DG 800CW tracer showed that the mean fluorescence intensity in ESCC (n = 17) and high-grade dysplasia (HGD, n = 13) is higher (p < 0.05) compared to that in low-grade dysplasia (LGD) (n = 7) and to the normal esophagus adjacent to the tumor (n = 5). The sensitivity and specificity of 2-DG 800CW to detect HGD and ESCC is 80% and 83%, respectively (ROC = 0.85). We identified and validated GLUT1 as a promising molecular imaging target and demonstrated that fluorescent imaging after topical application of 2-DG 800CW can differentiate HGD and ESCC from LGD and normal esophagus.     

Segmented polymer networks based on poly(N-isopropyl acrylamide) and poly(tetrahydrofuran) as polymer membranes with thermo-responsive permeability

Segmented polymer networks (SPNs) containing a polymer with a lower critical solution temperature were prepared by free radical copolymerization of poly(tetrahydrofuran) (PTHF) bis-macromonomers with N-isopropyl acrylamide (NIPAA). The PTHF bis-macromonomers, which were prepared by living cationic polymerization of tetrahydrofuran, were provided with acrylate or acrylamide end-groups by end-capping the living polymer chains with acrylic acid and 3-acrylaminopropanoic acid, respectively. Differential Scanning Calorimetry (DSC) experiments showed clearly that, for the same fractions of both network components, the phase morphology of the SPNs was highly influenced and adjustable by the nature of the end-groups of the bis-macromonomer as a result of their copolymerization behavior with NIPAA. For the same type of multi-component networks, the morphology changed from a heterogeneous up to a rather homogeneous nature by application of bis-macromonomers with, respectively, acrylate or acrylamide end-groups during their preparation. Swelling and DSC experiments on the swollen SPNs revealed, respectively, that the swelling properties and the cloud point temperature (T_cp) could be controlled by the network composition. The thermo-responsive water permeability and the possible application of the SPNs as pervaporation membranes for the separation of a water/isopropanol mixture were investigated as a function of temperature and network composition. The permeability and selectivity of the membranes decrease when the T_cp is reached. The permeability increases while the selectivity decreases with decreasing crosslink density or higher overall hydrophilicity of the SPNs.     

PERSIST: Policy-Based Data Management Middleware for Multi-Tenant SaaS Leveraging Federated Cloud Storage

NoSQL data stores are often combined to address different requirements within the same application. The implication of this trend is particularly important and relevant in the context of multi-tenant SaaS applications where tenants commonly have different storage- and privacy-related requirements and thus they desire to customize the storage setup according to their specific needs. Consequently, application developers are increasingly combining storage resources: on-premise and public cloud resources in a hybrid cloud setup, different external public cloud storage resources and providers in a federated cloud storage setup, etc. The consequences of these trends are twofold: (i) application developers and SaaS providers have to deal with heterogeneous technologies, different APIs, and implement complex storage logic (to address different requirements of tenants), all within the application layer; and (ii) storage architectures have become less rigid, and techniques are required to flexibly change the storage configuration of running applications, up to the level of individual service requests. To address these challenges, we present PERSIST, a middleware architecture that (i) externalizes the complexity of a federated cloud storage architecture and the complex storage logic from the SaaS application to storage policies, allows tenants to enforce different storage- and privacy-related requirements at a fine-grained level; and (ii) supports the dynamic (re)configurability of the underlying federated cloud storage architecture. Application-specific policies can be customized by individual tenants at run time, and PERSIST offers support for run-time cross-provider polyglot persistence and the confidentiality of sensitive data through encryption. We have validated PERSIST in a working prototype implementation. Our extensive evaluation efforts show (i) the accomplished reduction in the required development effort to support complex storage policies, (ii) the reduction in cost/effort to change the data storage architecture itself, and finally (iii) the acceptability of the performance overhead (around 6% for insert, and 2% for read, update and delete transactions).     

PROBA-V mission for global vegetation monitoring: standard products and image quality

PROBA-V is a new global vegetation monitoring mission, to be launched in the second quarter of 2013. PROBA-V has been developed to show a consistent performance with SPOT-VEGETATION (SPOT-VGT) data, with similar spectral bands but with an improved spatial resolution of 1/3 km. The innovative mission concept has led to several key research topics related to image quality, which are discussed in this article. To support the existing VEGETATION user community, the data products for PROBA-V continue to provide daily top of canopy synthesis (S1-TOC) and 10 day synthesis products (S10-TOC). In addition, the new top of atmosphere daily synthesis (S1-TOA) products and a radiometrically/geometrically corrected (level 1C) product in raw resolution will also be provided for scientific users.