非线性地基上桩结构物空间分析

本文提出了桩结构物－非线性地基空间相互作用分析的迭代法和非线性有限元法。其中，桩基分析用ｐ－ｙ曲线法。结合实际结构物进行了大量的计算及比较分析，成果是令人满意的，可以付诸应用。     

组合式光纤流量传感器

提出了一种新型的组合式光纤流量传感器，介绍了它的工作原理，详细讨论了光脉冲转换器的设计要点，据此设计了传感头，并给出了它的实验结果。     

高灵敏度荧光显微镜及其在细胞光敏效应研究中的应用

研制了一种可探测极微弱细胞荧光图象的高灵敏度荧光显微镜，在仪器中使用了一个高质量的亮度增益为５０，０００的象增强器对细胞的荧光图象进行光能量放大，因而这种荧光显微镜可探测到普通荧光显微镜不能观察的微弱荧光图象。由于仪器中光源的输出强度很小，避免了长时间观察对活细胞的光损伤，并可观察到荧光效率低的荧光物质的分布图象。探测系统中用计算机采集图象数据，同时对数据进行必要处理，以提高图象的质量。这种高灵敏度的荧光显微镜可用于分析细胞中荧光物质的分布，以及细胞动态生理过程的研究。使用此仪器已直接观察到光敏竹红菌甲素在Ｈｅｌａ细胞（人体宫颈癌细胞）中的分布，细胞受光照射后的光损伤现象及加入三种细胞保护剂后获得不同程度保护的细胞状态。     

微型集散系统通用过程控制软件包

本文给出一种新的基于ＭＣＳ－５１单片机集散系统通用过程控制软件包的设计原理及其实施方法。文中重点地阐述了微型集散系统的构在民，通用过程控制软件的自动生成，主要数据结构与程序结构，实现方法及关键技术等。本软件包是采用ＴＵＲＢＯＣ２．０版本和ＭＣＳ－５１泄编语言编程的，并通过了ＭＣＳ－５１组合软件的编译，形成了可用的目标码程序系统。     

An object-oriented manufacturing control system

This paper presents the development of an event-driven control architecture and its implementation in a physical simulator of a computerized manufacturing system using object-oriented techniques. The architecture was developed to improve the efficiency of handling concurrent control events in the DOS environment. In the implementation, the control system of the physical simulator consists of four distinct layers of control devices: a PC/386 computer, a microcontroller, I/O modules and the system's control devices such as motors, solenoids and sensors. A control program residing in the PC/386 coordinates system-level tasks such as event scheduling, while a BASIC program running on the microcontroller handles all low-level control tasks such as sensor monitoring and motion control. The concepts and developments presented in this paper should help in implementing an efficient control system for both CIM systems and their physical simulators.     

制备2，4－二氯－5－氟苯甲酰乙酸甲酯的缩合剂及工艺研究

通过３种不同的碱来制备２，４－二氯－５－氟苯甲酰乙酸甲酯，优选得到了其最佳缩合剂甲醇钠；同时应用正交设计实验，研究了原料配比、反应时间、反应温度对收率的影响，在优选条件下收率为７８．５％。     

Antiarrhythmic effect related to the plasma concentration of pentisomide in vivo and the antiarrhythmic-concentration relationship in vitro

Pentisomide, 2-(2-diisopropylaminoethyl)-4-methyl-2-(pyridyl)- pentanamide, is a novel antiarrhythmic agent structurally related to disopyramide. Using a glass bead arrhythmic model, the authors studied the antiarrhythmic effect of pentisomide in dogs by monitoring the plasma concentrations. When pentisomide was infused at 1 mg/kg/min for 20 min, the ventricular tachycardia was significantly reduced at 5 min after starting the infusion; the arrhythmias were reduced to less than 5% at the end of the 20 min infusion. The plasma-free concentration of pentisomide was about 3 micrograms/ml at 5 min; it increased to about 10 micrograms/ml at the end of 20 min infusion. With 0.3 mg/kg/min infusion, the arrhythmias were reduced to about 60% but were not significant at 20 min of infusion. The plasma-free concentration of pentisomide did not reach 3 micrograms/ml until 20 min of infusion. The 3 micrograms/ml plasma-free concentration for pentisomide seems to be a critical concentration in inducing a significant antiarrhythmic effect. Pentisomide dose-dependently inhibited ischaemia-reperfusion arrhythmia at doses of 30 microM and higher concentrations in vitro. In conclusion, pentisomide inhibits arrhythmias dependent with the plasma concentration or with the concentration of the external solution. The critical plasma-free concentration for inhibition of arrhythmias was 3 micrograms/ml (not equal to 10 microM) and the in vitro effect also had a similar concentration. Therefore, the in vivo and in vitro antiarrhythmic concentrations were well correlated.     

Surgical treatment of unilateral alveolar cleft

In this study, 16 cases of unilateral alveolar cleft with cleft lip and palate were repaired with autografts of cancellous bone (13 cases) or hydroxyapatite (3 cases). The grafts were covered by reflected mucoperiosteal flaps and a mucosal flap from the upper lip. Twelve of the thirteen cases were followed up for 1-5 years. Nine of whom using cancellous bone had bony continuity of the maxilla and 7 cases erupted permanent maxillary canines within the area of autografts. None of the 3 cases using hydroxyapatite erupted a canine tooth. The results showed that autograft was better than hydroxyapatite in terms of maxillary canine eruption.     

Histomorphometric study in children with idiopathic nephrotic syndrome

There is agreement on the clinical diagnostic criteria for acute inflammatory demyelinating polyneuropathy (AIDP/GBS) however, there is lack of consensus for detection of demyelination. In order to critically evaluate the prevailing criteria, sixty-six patients who fulfilled NINCDS criteria and had typical features of GBS were studied for electrophysiological abnormalities of peripheral nerves by using standard methods (median, common peroneal, sural and ulnar) between 1 to 12 weeks after the onset of symptoms. The commonest abnormality on motor nerve conduction study was prolonged distal latency (75%-83%) followed by reduction in CMAP amplitude (63%-82%), decreased velocity (48%-62%), conduction block (17%-39%) and f-wave abnormalities (37.8%-59%). Sensory conduction abnormalities were detected in over 20% of median, 25% of ulnar and 33% of sural nerves. All the patients had abnormality of at least two motor conduction parameters in one nerve when values beyond 2 SD of the mean were considered abnormal and over 70% of patients had three abnormalities in two nerves or two abnormalities in three nerves. Comparison with the prevailing criteria for demyelination revealed that the number of patients fulfilling them varied widely: Albers et al. (1985): 74.2%, Albers et al. (1989): 40.9% and Cornblath: 30.3%. We believe that the current criteria for detection of demyelination in acute neuropathy are too strict, underestimate the underlying pathology in GBS and need reassessment.