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81.
Cognition, Technology & Work - For a successful market introduction of Level 3 Automated Driving Systems (L3 ADS), a careful evaluation of human–machine interfaces (HMIs) is necessary....  相似文献   
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83.
This paper is focused on the retrieval of industrial aerosol optical thickness (AOT) and microphysical properties by means of airborne imaging spectroscopy. Industrial emissions generally lead to optically thin plumes requiring an adapted detection method taking into account the weak proportion of particles sought in the atmosphere. To this end, a semi-analytical model combined with the Cluster-Tuned Matched Filter (CTMF) algorithm is presented to characterize those plumes, requiring the knowledge of the soil under the plume. The model allows the direct computation of the at-sensor radiance when a plume is included in the radiative transfer. When applied to industrial aerosol classes as defined in this paper, simulated spectral radiances can be compared to ‘real’ MODTRAN (Moderate Resolution Atmospheric Transmission) radiances using the Spectral Angle Mapper (SAM). On the range from 0.4 to 0.7 µm, for three grounds (water, vegetation, and bright one), SAM scores are lower than 0.043 in the worst case (a both absorbing and scattering particle over a bright ground), and usually lower than 0.025. The darker the ground reflectance is, the more accurate the results are (typically for reflectance lower than 0.3). Concerning AOT retrieval capabilities, with a pre-calculated model for a reference optical thickness of 0.25, we are able to retrieve plume AOT at 550 nm in the range 0.0 to 0.4 with an error usually ranging between 9% and 13%. The first test case is a CASI (Compact Airborne Spectrographic Imager) image acquired over the metallurgical industry of Fos-sur-Mer (France). First results of the use of the model coupled with CTMF algorithm reveal a scattering aerosol plume with particle sizes increasing with the distance from the stack (from detection score of 54% near the stack for particles with a diameter of 0.1 µm, to 69% away from it for 1.0 µm particles). A refinement is made then to estimate more precisely aerosol plume properties, using a multimodal distribution based on the previous results. It leads to find a mixture of sulfate and brown carbon particles with a plume AOT ranging between 0.2 and 0.5. The second test case is an AHS (Airborne Hyperspectral Scanner) image acquired over the petrochemical site of Antwerp (Belgium). The first CTMF application results in detecting a brown carbon aerosol of 0.1 µm mode (detection score is 51%). Refined results show the evolution of the AOT decreasing from 0.15 to 0.05 along the plume for a mixture of brown carbon fine mode and 0.3 µm radius of sulfate aerosol.  相似文献   
84.
Wall roughness plays a crucial role in granular medium - rough wall interface friction. In this study, an experimental device has been designed to study the influence of boundary conditions, more specifically wall roughness, on the behavior of sheared granular medium. The study is based on use of an analog model, and consists of simulating roughness by means of notches and grains in the medium by monodisperse beads and on use of a numerical model based on the discrete element method. The test protocol entails displacing at fixed speed notched rods under confined granular medium. Movement of the beads layer near the rods as well as friction of the beads against the rods are both studied herein. Results indicate that the parameter controlling friction at the granular medium - rough wall interface is primarily the depth of beads embedment in surface asperities. The objective of the associated numerical modeling is to supplement the experimental results.  相似文献   
85.
Countless bibliometric indexes have been proposed to assess researchers’ productivities, in particular, in fields where the author sequence is regarded helpful in determining authors’ individual credits. Unfortunately, the most popular h-index ignores author ranks and leads to bias with multi-author publications; and of the many bibliometric counting methods proposed for assigning credit to authors, such as harmonic or geometric counting, none seems to have been widely adopted yet. In this work, I challenge the assumption that the total credit for a publication be equal to 1. This total-credit normalization assumption diminishes first-author credit and may impede adoption of multi-author-aware credit assignment rules. Other than on relative contributions, author credit could be based on variables such as accountability, which remains unchanged for the first (and potentially, the last) author regardless of additional coauthors. Therefore, I study the adequacy of several counting methods for first-author-normalized credit, giving full credit to the first author while also crediting coauthors. Harmonic counting has been shown to agree well with empirical data; however, unlike geometric counting, harmonic counting results in unbounded total credit for a publication with first-author-credit normalization in the limit of many authors. I therefore propose adaptable geometric counting and evaluate how it combines the advantages of harmonic and geometric counting through an additional parameter. I show that the golden ratio is a parameter for geometric counting that agrees as well as harmonic counting with empirical data for total-credit normalization; and I discuss the impact of using adaptable geometric counting with first-author-normalized credit. In particular, the latter features bounded total credits even when full credit is given to first authors. In conclusion, geometric counting with the golden ratio can be used for credit assignment without having to choose a parameter value, yet offers customization potential and can be combined with either normalization assumption.  相似文献   
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87.
Structural and Multidisciplinary Optimization - In this article, we present simple and robust numerical methods for two-dimensional geometrical shape optimization problems, in the context of...  相似文献   
88.
Multimedia Tools and Applications - Segmentation of white blood cell nucleus is a crucial step in white blood cell counting and classification system based on peripheral blood smear images. It is...  相似文献   
89.
High-level synthesis (HLS) is a potential solution to increase the productivity of FPGA-based real-time image processing development. It allows designers to reap the benefits of hardware implementation directly from the algorithm behaviors specified using C-like languages with high abstraction level. In order to close the performance gap between the manual and HLS-based FPGA designs, various code optimization forms are made available in today’s HLS tools. This paper proposes a HLS source code and directive manipulation strategy for real-time image processing by taking into account the applying order of different optimization forms. Experiment results demonstrate that our approach can improve more effectively the test implementations comparing to the other optimization strategies.  相似文献   
90.
The tropical diseases human African trypanosomiasis, Chagas disease, and the various forms of leishmaniasis are caused by parasites of the family of trypanosomatids. These protozoa possess a unique redox metabolism based on trypanothione and trypanothione reductase (TR), making TR a promising drug target. We report the optimization of properties and potency of cyclohexylpyrrolidine inhibitors of TR by structure‐based design. The best inhibitors were freely soluble and showed competitive inhibition constants (Ki) against Trypanosoma (T.) brucei TR and T. cruzi TR and in vitro activities (half‐maximal inhibitory concentration, IC50) against these parasites in the low micromolar range, with high selectivity against human glutathione reductase. X‐ray co‐crystal structures confirmed the binding of the ligands to the hydrophobic wall of the “mepacrine binding site” with the new, solubility‐providing vectors oriented toward the surface of the large active site.  相似文献   
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