Synthesis and characterization of 2‐hydroxyethylmethacrylate/2‐(3‐indol‐yl)ethylmethacrylamide‐based novel hydrogels as drug carrier with in vitro antibacterial properties

In this study, a new cationic monomer 2‐(3‐indol‐yl)ethylmethacrylamide (IEMA) derived from tryptamine was synthesized in a single step and characterized by Fourier transform infrared (FTIR), ¹H‐NMR, and ¹³C‐NMR. Then, one‐step preparation of novel poly[2‐hydroxyethylmethacrylate‐c‐2‐(3‐indol‐yl)ethylmethacrylamide], or p(HEMA‐c‐IEMA), copolymeric hydrogels has been performed successfully with IEMA and 2‐hydroxyethylmethacrylate (HEMA) as monomers using free radical aqueous polymerization. The hydrogels were characterized with scanning electron microscopy, FTIR, elemental analysis, thermogravimetric analysis, and texture profile analysis instruments. p(HEMA‐c‐IEMA) hydrogels were used for swelling, diffusion, drug release, and antibacterial activity studies. The drug‐release behavior of the hydrogels was determined as a function of time at 37 °C in pH 1.2 and 7.2. The swelling and drug‐release studies showed that an increased IEMA amount caused a higher increase in swelling and drug‐release values. Additionally, zero‐order, first‐order, and Higuchi equation kinetic models were applied to the drug‐release data, and the data fit well in the Higuchi model, and the Peppas power‐law model was applied to the release mechanism. Finally, the antibacterial activities of the hydrogels were screened against Gram‐positive bacteria (Bacillus cereus and Staphylococcus aureus) and Gram‐negative bacteria (Escherichia coli and Salmonella typhimurium). © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134, 45550.     

Similarity queries: their conceptual evaluation, transformations, and processing

Many application scenarios can significantly benefit from the identification and processing of similarities in the data. Even though some work has been done to extend the semantics of some operators, for example join and selection, to be aware of data similarities, there has not been much study on the role and implementation of similarity-aware operations as first-class database operators. Furthermore, very little work has addressed the problem of evaluating and optimizing queries that combine several similarity operations. The focus of this paper is the study of similarity queries that contain one or multiple first-class similarity database operators such as Similarity Selection, Similarity Join, and Similarity Group-by. Particularly, we analyze the implementation techniques of several similarity operators, introduce a consistent and comprehensive conceptual evaluation model for similarity queries, and present a rich set of transformation rules to extend cost-based query optimization to the case of similarity queries.     

Assessment of Fire Risk in the Readymade Garment Industry in Dhaka,Bangladesh

Readymade garments are the most important export item from Bangladesh, yet the working conditions and fire safety records in the factories are often not up to the standard. Despite a number of initiatives to curb fire accidents in the garment industry, there are still a significant number of fire occurrences in this industry. Unfortunately, there is no comprehensive statistics on the current status of fire provisions and management practices in the readymade garment factories in Bangladesh. Given the management practices (soft issues) are often as important as structural fire safety measures, yet difficult to regulate, this paper develops a fire risk index (FRI), the first of its kind in Bangladesh, for soft parameters in the garment industry. FRI for 60 random garment factories are developed through surprise inspections to understand the current status of fire risk due to inadequacies in the soft parameters. Results show that the mean FRI is 2.8 on a scale of 5.0, which indicates an alarming condition. Locked exit doors, lack of emergency announcement system and lack of fire drills are the three worst performers among the 24 investigated parameters and require immediate attention from the regulators and stakeholders. We also observed a U-shaped relationship between FRI and factory size. Factories that are members of the industry’s trade lobby generally have better fire safety practices than the non-members. Given the importance of the readymade garment sector in many developing countries, poor fire safety record and lack of information on fire safety, our approach of developing an FRI for the industry can be very useful to understand the immediate concerns and thus to curb fatalities and injuries from fire accidents in this sector.     

Experimental study of the fatigue characteristics and reliability of continuous welded rails

In recent years, joint types in railway superstructure have shifted to continuous welded rails (CWRs), which can be constructed by various welding techniques to form uninterrupted rails several kilometres long. Because of the numerous advantages of this method, CWR systems are highly preferred today for the construction of new railway lines. The increase in the number of trains in operation is inducing fatigue damages, linking to life‐threatening risks in the rails as well as in trains' wheels and axles. In this study, CWR specimens formed by the flash butt‐welding process are investigated. Specimens extracted from rail sections are subjected to four‐point bending fatigue tests to establish S–N curves under various loading levels. The surfaces of those specimens which fail are then investigated in detail in order to determine the initiation points of the failures. The findings provide experimental data on the dynamic life cycle of CWR and identify the failure mechanism of the CWR system.     

Economic analysis of standalone and grid connected hybrid energy systems

A pilot region was selected and cost analysis of using renewable energy sources with a hydrogen system for that region’s energy demand is introduced, in a techno-economic perspective, in this paper. The renewable energy potential for the region was evaluated by implementing energy cost analysis. The study also evaluates the feasibility of utilizing solar and wind energy with hydrogen as a storage unit to meet the electricity requirements of the pilot region as a standalone system and in conjunction with the conventional grid based electricity.In order to simulate the operation of the system and to calculate the technical and economic parameters, micropower optimization program Homer (NREL, US) was used in this study. Homer requires some input values, such as technological options, cost of components, and resource compliance; and then the program ranges the feasible system configurations according to the net present cost (system cost) by using these inputs.The pilot region in this study, where the renewable based energy will be used, is determined to be Electrics & Electronics Faculty, Istanbul Technical University.