AbstractA series of Cu-K/Al2O3 catalysts were synthesized by wet impregnation technique. The reduced catalysts were further used for conversion of carbon dioxide to methane and carbon monoxide. Moreover, the fresh and used catalysts were characterized to investigate the changes in the surface morphology, metal dispersion, surface area, crystalline phases, and functional groups of studied catalysts. The SEM analysis of fresh and spent catalysts showed no remarkable difference in surface morphology with irregular shaped agglomerated particles. Furthermore, TEM micrographs presented the well distribution of metal catalyst over alumina support. The decrease in surface area from 115 to 77?m2/g for Cu1.62-K0.5/Al2O3 after reaction was related to sintering and oxidation of catalyst during reaction. XRD revealed the disappearance of some minor peaks which can be associated with the sintering of spent catalyst. FTIR also presented some new peak for spent catalyst which can be linked with metal oxides. Moreover, various reaction conditions of temperature (230, 400, and 600?°C), pressure (1 and 7?bar), and feed molar ratio of H2/CO2 (2:1 and 4:1) were investigated using different Cu loading (0, 1, 1.25, 1.62, and 4 weight percent). A maximum CO2 conversion of 63% with 39% CH4 selectivity was achieved by using Cu1.62-K0.5/Al2O3 at 600?°C, molar ratio of H2/CO2 4 under 7?bar. The presence of K on the surface of synthesized catalyst increased the CO2 conversion from 48% (Cu1/Al2O3) to 55% (Cu1-K0.5/Al2O3) at above mentioned reaction conditions which suggested the promoter effect of K during conversion of carbon dioxide. 相似文献
Aspergillus species are ubiquitous environmental moulds, with spores inhaled daily by most humans. Immunocompromised hosts can develop an invasive infection resulting in high mortality. There is, therefore, a pressing need for host-centric therapeutics for this infection. To address it, we created a multi-scale computational model of the infection, focused on its interaction with the innate immune system and iron, a critical nutrient for the pathogen. The model, parameterized using published data, was found to recapitulate a wide range of biological features and was experimentally validated in vivo. Conidial swelling was identified as critical in fungal strains with high growth, whereas the siderophore secretion rate seems to be an essential prerequisite for the establishment of the infection in low-growth strains. In immunocompetent hosts, high growth, high swelling probability and impaired leucocyte activation lead to a high conidial germination rate. Similarly, in neutropenic hosts, high fungal growth was achieved through synergy between high growth rate, high swelling probability, slow leucocyte activation and high siderophore secretion. In summary, the model reveals a small set of parameters related to fungal growth, iron acquisition and leucocyte activation as critical determinants of the fate of the infection. 相似文献
Loop‐mediated isothermal amplification (LAMP) is a novel method that amplifies target nucleic acids under isothermal conditions. It is a rapid, specific, and sensitive method, which does not require costly thermal cyclers for the detection of nucleic acids. Thus, it is suitable for on‐site detection assays under low‐resource settings. It can also be integrated on compact lab‐on‐a‐chip devices for the development of micro‐total analysis systems. This review discusses LAMP‐based methods, as well as LAMP‐based centrifugal, microfluidic, and other fluid‐handling devices, which have been developed for the assessment of meat quality parameters that are related to the presence or absence of nucleic acids, for example, animal species identification and microbiological quality. Advances in improving the rapidity, specificity, and sensitivity of LAMP techniques for the assessment of these meat quality parameters are also discussed in this review. 相似文献
The corrosion resistance of conventional and high alloy stainless steels (specifically 316L, 317L, 904L, duplex 2205, 3127hMO, 1925hMO, 254SMO, 654SMO and Remanit-4565) was determined electrochemically in chlorinated and unchlorinated Arabian Gulf Seawater at 25 and 50 °C. The stainless steels 316L and 317L were used as reference alloys. The electrochemical potentiodynamic cyclic polarization method was used to determine the passive film break down potential (Eb), protection potential (Eprot) and maximum current attained on scan reversal (Imax). It was found that at 25 °C in chlorinated and unchlorinated seawater and at 50 °C in unchlorinated seawater, stainless steels 316L and 317L have poor resistance to corrosion, Stainless steels 904L and duplex 2205 at 25 °C in chlorinated and unchlorinated seawater showed good resistance to corrosion but at 50 °C these steels failed to resist. The high alloy stainless steels such as 3127hMO, 1925hMO, 254SMO, 654SMO and Remanit-4565 showed better corrosion resistance under all the test conditions. 相似文献
A new alternating double aquo-bridged and single cyano-bridged polymeric complex {[Ba2(phen)4(H2O)6Fe(CN)6]·Cl·2(phen)·3H2O}n (1) (phen = 1,10-phenanthroline) has been synthesized and structurally characterized. In the crystal structure the two centrosymmetric [Ba2(phen)4(H2O)6] units are bridged through two trans CN groups of [Fe(CN)6]3− ion, which results in the formation of a zig-zag polymeric chain. In each [Ba2(phen)4(H2O)6] unit, the two Ba centers are joined by double aquo bridges. Both the Ba atoms are 9-coordinated with distorted mono-capped square antiprismatic geometry. An elaborate hydrogen bonding system holds the parallel polymeric chains together. 相似文献
This work presents experimental, modeling and simulation studies for Co2+ ion extraction using hollow fiber supported liquid membrane (HFSLM) operated in a recycling mode. Extractant di-(2-ethylhexyl) phosphoric acid (D2EHPA) diluted with kerosene has been used as the membrane phase. The Co2+ ion concentration in the aqueous feed phase was varied in the range of 1–3 mM. Also, D2EHPA concentration was varied in the range of 10–30% (v/v). A mass transfer model has been developed considering the complexation and de-complexation reactions to be fast and at equilibrium. Equations for extractant mass balance and counter-ion (H+) transport have also been incorporated in the model. Extraction equilibrium constant (Kex) for cobalt–D2EHPA system has been estimated from equilibration experiments and found to be 3.48 × 10−6. It was observed that the model results are in good agreement with the experimental data when diffusivity of metal-complex (Dm) through the membrane phase is 1.5 × 10−10 m2/s. Feed phase pH and strip phase acidity had negligible effect on the extraction profiles of Co2+ ions. An increase in D2EHPA concentration increased extraction rates of Co2+ ions. The membrane phase diffusion step was found to be the controlling resistance to mass transfer. 相似文献
The gross calorific value (GCV) is an important property defining the energy content and thereby efficiency of fuels, such as coals. There exist a number of correlations for estimating the GCV of a coal sample based upon its proximate and/or ultimate analyses. These correlations are mainly linear in character although there are indications that the relationship between the GCV and a few constituents of the proximate and ultimate analyses could be nonlinear. Accordingly, in this paper a total of seven nonlinear models have been developed using the artificial neural networks (ANN) methodology for the estimation of GCV with a special focus on Indian coals. The comprehensive ANN model developed here uses all the major constituents of the proximate and ultimate analyses as inputs while the remaining six sub-models use different combinations of the constituents of the stated analyses. It has been found that the GCV prediction accuracy of all the models is excellent with the comprehensive model being the most accurate GCV predictor. Also, the performance of the ANN models has been found to be consistently better than that of their linear counterparts. Additionally, a sensitivity analysis of the comprehensive ANN model has been performed to identify the important model inputs, which significantly affect the GCV. The ANN-based modeling approach illustrated in this paper is sufficiently general and thus can be gainfully extended for estimating the GCV of a wide spectrum of solid, liquid and gaseous fuels. 相似文献
The mu opioid receptor has a distinct place in the opioid receptor family, since it mediates the actions of most opioids used clinically (e.g., morphine and fentanyl), as well as drugs of abuse (e.g., heroin). The single-copy mu opioid receptor gene, OPRM1, goes through extensive alternative pre-mRNA splicing to generate numerous splice variants that are conserved from rodents to humans. These OPRM1 splice variants can be classified into three structurally distinct types: (1) full-length 7 transmembrane (TM) carboxyl (C)-terminal variants; (2) truncated 6TM variants; and (3) single TM variants. Distinct pharmacological functions of these splice variants have been demonstrated by both in vitro and in vivo studies, particularly by using several unique gene-targeted mouse models. These studies provide new insights into our understanding of the complex actions of mu opioids with regard to OPRM1 alternative splicing. This review provides an overview of the studies that used these gene-targeted mouse models for exploring the functional importance of Oprm1 splice variants. 相似文献
Massive MIMO (also known as the “Large-Scale Antenna System”) enables a significant reduction of latency on the air interface with the use of a large excess of service-antennas over active terminals and time division duplex operation. For large-scale MIMO, several technical issues need to be addressed (e.g., pilot pattern design and low-antenna power transmission design) and theoretically addressed (e.g., channel estimation and power allocation schemes). In this paper, we analyze the ergodic spectral efficiency upper bound of a large-scale MIMO, and the key technologies including channel uplink detection. We also present new approaches for detection and power allocation. Assuming arbitrary antenna correlation and user distributions, we derive approximations of achievable rates with linear detection techniques, namely zero forcing, maximum ratio combining, minimum mean squared error (MMSE) and eigen-value decomposition power allocation (EVD-PA). While the approximations are tight in the large system limit with an infinitely large number of antennas and user terminals, they also match our simulations for realistic system dimensions. We further show that a simple EVD-PA detection scheme can achieve the same performance as MMSE with one order of magnitude fewer antennas in both uncorrelated and correlated fading channels. Our simulation results show that our proposal is a better detection scheme than the conventional scheme for LSAS. Also, we used two channel environment channels for further analysis of our algorithm: the Long Term Evolution Advanced channel and the Millimeter wave Mobile Broadband channel.
Aqueous solution properties of polyethylene oxide–block-polypropylene oxide–block-polyethylene oxide TBP [(PEO)103(PPO)39(PEO)103] were studied in the presence of sodium salts with different anions (NaI, NaBr, NaCl, NaF, Na2SO4, Na3PO4) to investigate unimer-to-micelle transition [critical micelle concentration (CMC), critical micellization temperature (CMT)],
micelle size and the phase separation (cloud point). This TBP, due to its very hydrophilic (80% PEO) nature does not form
micelles at ambient temperatures. Micellization can be induced much below its CMT in water on addition of sodium salts having
different anions. Analytical methods viz. fluorescence, FTIR and dynamic light scattering (DLS) were used to monitor the salt-induced
micellization. The hydration of respective anion and resultant contribution to its salting-out effect was found to be the
governing factor in promoting micellization. The presence of salt decreases the CMC, CMT and phase separation temperature.
The salts affect the aggregation process in agreement with an order mentioned in Hofmeister series. 相似文献