Application potential of bone marrow mesenchymal stem cell (BMSCs) based tissue-engineering for spinal cord defect repair in rat fetuses with spina bifida aperta

Spina bifida aperta are complex congenital malformations resulting from failure of fusion in the spinal neural tube during embryogenesis. Despite surgical repair of the defect, most patients who survive with spina bifida aperta have a multiple system handicap due to neuron deficiency of the defective spinal cord. Tissue engineering has emerged as a novel treatment for replacement of lost tissue. This study evaluated the prenatal surgical approach of transplanting a chitosan–gelatin scaffold seeded with bone marrow mesenchymal stem cells (BMSCs) in the healing the defective spinal cord of rat fetuses with retinoic acid induced spina bifida aperta. Scaffold characterisation revealed the porous structure, organic and amorphous content. This biomaterial promoted the adhesion, spreading and in vitro viability of the BMSCs. After transplantation of the scaffold combined with BMSCs, the defective region of spinal cord in rat fetuses with spina bifida aperta at E20 decreased obviously under stereomicroscopy, and the skin defect almost closed in many fetuses. The transplanted BMSCs in chitosan–gelatin scaffold survived, grew and expressed markers of neural stem cells and neurons in the defective spinal cord. In addition, the biomaterial presented high biocompatibility and slow biodegradation in vivo. In conclusion, prenatal transplantation of the scaffold combined with BMSCs could treat spinal cord defect in fetuses with spina bifida aperta by the regeneration of neurons and repairmen of defective region.     

气相色谱仪新旧检定规程的解读

本文主要从规程适用范围、计量器具控制、计量性能要求及检定方法等方面入手,全面的解读了气相色谱仪新旧检定规程的差异,为仪器检定及期间核查提供了参考。     

Regulation of Polymer Configurations Enables Green Solvent-Processed Large-Area Binary All-Polymer Solar Cells With Breakthrough Performance and High Efficiency Stretchability Factor

With the great potential of the all-polymer solar cells for large-area wearable devices, both large-area device efficiency and mechanical flexibility are very critical but attract limited attention. In this work, from the perspective of the polymer configurations, two types of terpolymer acceptors PYTX-A and PYTX-B (X = Cl or H) are developed. The configuration difference caused by the replacement of non-conjugated units results in distinct photovoltaic performance and mechanical flexibility. Benefiting from a good match between the intrinsically slow film-forming of the active materials and the technically slow film-forming of the blade-coating process, the toluene-processed large-area (1.21 cm²) binary device achieves a record efficiency of 14.70%. More importantly, a new parameter of efficiency stretchability factor (ESF) is proposed for the first time to comprehensively evaluate the overall device performance. PM6:PYTCl-A and PM6:PYTCl-B yield significantly higher ESF than PM6:PY-IT. Further blending with non-conjugated polymer donor PM6-A, the best ESF of 3.12% is achieved for PM6-A:PYTCl-A, which is among the highest comprehensive performances.     

Implementation of pseudo-nondiffracting beams by use of diffractive phase elements

We report the experimental implementation of pseudo-nondiffracting beams by use of diffractive phase elements (DPE's). Based on the conjugate-gradient method presented in J. Opt. Soc. Am. A 15, 144-151 (1998), these DPE's are designed and fabricated on a flat quartz substrate. The experimental results show that the performance of the fabricated DPE's is in good agreement with the theoretical prediction.     

A network-based mobility management scheme for future Internet

The current Internet was originally designed for “fixed” terminals and can hardly support mobility. It is necessary to develop new mobility management schemes for the future Internet. This paper proposes an Identifiers Separating and Mapping Scheme (ISMS), which is a candidate for the future Internet mobility management, and discusses the basic principles and detailed message flow. ISMS is a network-based mobility management scheme that takes advantage of the identity and location separation. The mobility entities in the core network are responsible for the location management. ISMS is designed to satisfy the requirements of faster handover, route optimism, advanced management, location privacy and security. The average handover delay of ISMS is on the order of milliseconds only, which is far smaller than that of Mobile IPv6. Analyses show that ISMS can reduce packet overhead on wireless channels. We build a prototype and perform some experiments. Results verify the feasibility of ISMS.     

Embedding multi-dimensional meshes into twisted cubes

The twisted cube is an important variant of the most popular hypercube network for parallel processing. In this paper, we consider the problem of embedding multi-dimensional meshes into twisted cubes in a systematic way. We present a recursive method for embedding a family of disjoint multi-dimensional meshes into a twisted cube with dilation 1 and expansion 1. We also prove that a single multi-dimensional mesh can be embedded into a twisted cube with dilation 2 and expansion 1. Our work extends some previously known results.     

未雨绸缪 防患未然——“柔性测试”助力泛华测控提供高可靠性测试系统

<正>毋庸置疑,"可靠性"一直是评价电子产品性能的关键词之一,尤其在军工、航天等领域,产品的可靠性更是具有举足轻重的地位。一个细小器件的故障引发系统重大事故的案例屡见不鲜。随着人们对可靠性的重要性认识的不断提高,业内对可靠性理论及可靠性设计的研究也不断深入。12月2日,由中国电子