Occlusion of large atrial septal defects with a centering buttoned device: early clinical experience

A feasibility clinical study was conducted for the transcatheter occlusion of large ostium secundum atrial septal defects with the centering buttoned device. The centering buttoned device is a modification of the regular buttoned device in which a centering counter-occluder is sutured at the central 40% portion of the occluder. During centering it is stretched, forming a parachute-shaped structure and pulling the occluder over the center of the defect. During buttoning, the counter-occluder forms a double figure eight, opposing the right atrial side of the atrial septum. Occlusion was performed in 12 patients aged 6 to 56 years. All had been rejected for transcatheter occlusion by the regular buttoned device, because of either their defect size or the lack of adequate septal rim. The defect size varied between 23 and 31 mm, and the device size varied between 45 and 60 mm. Nine had immediate effective occlusions of their defects and three residual shunts. One patient with unbuttoning had hemolysis at 2 weeks and underwent surgery. Early results of the transcatheter occlusion of large atrial septal defects are promising, and larger clinical trials are justified.     

Localization of interferon-gamma and Ia-antigen in T cell line-mediated experimental autoimmune encephalomyelitis

This study reports the cellular localization of interferon-gamma (IFN-gamma) and MHC class II antigen (Ia) in the spinal cord of rats with experimental autoimmune encephalomyelitis induced by adoptive transfer of myelin basic protein-specific T cells. Numerous IFN-gamma-positive cells, stained with two different monoclonal antibodies against IFN-gamma, were present from days 3 to 7 after cell transfer. Their number was greatly reduced on day 10. A subpopulation of T cells was IFN-gamma positive. Moreover, a large number of ED1-positive macrophages contained IFN-gamma immunoreactivity. The transient presence of immune cells containing IFN-gamma immunoreactivity in experimental autoimmune encephalomyelitis suggests a pathogenic role of this cytokine in immune-mediated demyelination of the central nervous system.     

Prediction of evaporation heat transfer coefficient and pressure drop of refrigerant mixtures

A study on the prediction of heat transfer coefficient (HTC) and pressure drop of refrigerant mixtures is reported. HTCs and pressure drops of prospective mixtures to replace R12 and R22 are predicted on the same cooling capacity basis. Results indicate that nucleate boiling is suppressed at qualities greater than 20.0% for all mixtures and evaporation becomes the main heat transfer mechanism. For the same capacity, some mixtures containing R32 and R152a show 8.0–10.0% increase in HTCs. Some mixtures with large volatility difference exhibit as much as 55.0% reduction compared with R12 and R22, caused by mass transfer resistance and property degradation due to mixing (32.0%) and reduced mass flow rates (23.0%). Other mixtures with moderate volatility difference exhibit 20.0–30.0% degradation due mainly to reduced mass flow rates. The overall impact of heat transfer degradation, however, is insignificant if major heat transfer resistance exists in the heat transfer fluid side (air system). If the resistance in the heat transfer fluid side is of the same order of magnitude as that on the refrigerant side (water system), considerable reduction in overall HTC of up to 20% is expected. A study of the effect of uncertainties in transport properties on heat transfer shows that transport properties of liquid affect heat transfer more than other properties. Uncertainty of 10.0% in transport properties causes a change of less than 6% in heat transfer prediction.     

Still image coding based on vector quantization and fractalapproximation

In this paper, we propose a coding algorithm for still images using vector quantization (VQ) and fractal approximation, in which low-frequency components of an input image are approximated by VQ, and its residual is coded by fractal mapping. The conventional fractal coding algorithms indirectly used the gray patterns of an original image with contraction mapping, whereas the proposed fractal coding method employs an approximated and then decimated image as a domain pool and uses its gray patterns. Thus, the proposed algorithm utilizes fractal approximation without the constraint of contraction mapping. For approximation of an original image, we employ the discrete cosine transform (DCT) rather than conventional polynomial-based transforms. In addition, for variable blocksize segmentation, we use the fractal dimension of a block that represents the roughness of the gray surface of a region. Computer simulations with several test images show that the proposed method shows better performance than the conventional fractal coding methods for encoding still pictures.     

Taking the challenge of multiple access for third-generationcellular mobile radio systems-a European view

In Europe, the challenge of the design of third-generation cellular mobile radio systems has been taken numerous research and development activities in this field have been started. The authors try to give an overview of the European activities in this field. The article is organized in two parts. In the first part, the requirements for third-generation cellular mobile radio systems such as Universal Mobile Telecommunications System (UMTS) and Future Public Land Mobile Telecommunications System (FPLMTS), which has been named International Mobile Telecommunications after the year 2000 (IMT-2000) are presented concisely. Also, the importance and challenge of the multiple access design for such third-generation cellular mobile radio systems is explained. In the second part, numerous European research activities with focus on the multiple access design for third-generation cellular mobile radio systems are reviewed     

Performance analysis of linear multiuser detectors for randomlyspread CDMA using Gaussian approximation

The performance of a linear decorrelating detector (LDD) and a minimum mean square error (MMSE) detector is analyzed for random spreading waveforms. The performance of the LDD and MMSE detectors is expressed in terms of the so-called near-far resistance, defined by a reciprocal of a diagonal component of inverse matrix. For random code division multiple access, which employs random spreading waveforms, the near-far resistance can be regarded as a random variable. Many papers have dealt with the analysis of multiuser detectors for random spreading sequences. In most cases, however, these analyses derived only the expectations or bounds for the near-far resistance. In this paper, we directly derive the approximate probability density function (PDF) of the near-far resistance and corresponding bit error rate expression for random spreading sequences. It is based on Gaussian approximation of the cross correlation between any two randomly generated spreading codes. The resulting PDF turned out to be a reversed-and-scaled version of chi-square distribution. The approximate expressions, both the PDF and the corresponding bit error rate expression, were verified via Monte Carlo simulations. The results showed that the approximation is quite close to the simulation results when the number of users is less than half the processing gain     

A 44-GHz monolithic waveguide plane-wave amplifier with improvedunit cell design [using pHEMTs]

A 44-GHz monolithic waveguide plane-wave amplifier (PWA) with improved unit cell design is presented in this paper. The unit cell is a two-stage direct-coupled design and satisfies size, bistability, and stability requirements of the waveguide PWA. The ultra-compact unit cell had a cell size of 0.8 mm², and showed a small-signal gain of 8 dB and an output power of 15 dBm at 44 GHz with a corresponding dc-to-RF efficiency of 10%. A monolithic waveguide PWA using these unit cells showed a “flange-to-flange” gain of 5 dB, an output power of 0.3 W, and an efficiency of 2% at 44 GHz     

Energy release rates of crack kinking by boundary condition sensitivity analysis

The energy release rate, which is the total derivative of the energy with respect to crack length, is recognized as corresponding to the shape sensitivity analysis with the crack length change represented by the tangential component of design velocity. In this paper the sensitivity formula recently developed for a changing boundary condition has been further extended to cover crack kinking under mixed mode loading. Due to difficulty in defining the velocity field at the corner, the energy release rate at the onset of crack kinking is obtained by extrapolating the energy release rates for finite length kinked cracks. A rectangular plate with a single edge slant crack under uniform tension is taken as a numerical example. The multi-region technique in the numerical implementation of the boundary integral equation is adopted to consider the asymmetry of the problem. Excellent accuracy is observed as compared with reference analytic solutions.     

Aerodynamic effect on natural frequency and flutter instability in rotating optical disks

 Experimental studies on the aerodynamic coupling effect on natural frequencies and flutter instability of rotating disks are investigated in this paper. The experiments performed using a vacuum chamber and optical disks give two main results. One is that the aerodynamic effect by surrounding air reduces the natural frequencies and critical speeds of the vibration modes in pre-flutter regions. The other is that the natural frequency of the disk rotating at ambient atmospheric pressure is equal to that in vacuum at the flutter onset speed where the disk experiences aero-induced flutter. In post-flutter regions, the aerodynamic coupling between the disk and surrounding air increases the natural frequencies of the disk. Received: 17 June 2002/Accepted: 7 October 2002 The work was supported by Grant No. R11-1997-042-090001-0 of the Center for Information Storage Devices designated by the Korea Science & Engineering Foundation. Paper presented at the 13th Annual Symposium on Information Storage and Processing Systems, Santa Clara, CA, USA, 17–18 June, 2002     

On the current delivery limit of semiconducting carbon nanotubes

The current carrying capacity of single-walled semiconducting carbon nanotubes (CNTs) is studied by self-consistent quantum simulations using the non-equilibrium Green’s function formalism with the self-consistent Born approximation. The simulation shows that the current carrying capacity depends on the bias regime and is drastically different from that of metallic tubes. For long CNTs (with a length much longer than zone boundary and optical phonon scattering mean free path), the current saturates around 20 μA in the forward bias regime with unipolar transport due to phonon scattering. In ambipolar transport regime, the current delivery limit is still about 20 μA due to recombination of electron and hole currents. In contrast, for short semiconducting CNTs, the current delivery capacity can be above 25 μA in the unipolar transport regime and further double in the ambipolar transport regime. In reverse bias regime, the current of a long CNT can exceed 20 μA due to the second subband conduction and increased electron injection from the drain. The simulation provides a coherent explanation to the dependence of current delivery limit on bias regime and channel length, which is consistent with recent experiments.