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21.
Takashi Ijiri Kenshi Takayama Hideo Yokota Takeo Igarashi 《Computer Graphics Forum》2009,28(7):1821-1828
Animations of characters with flexible bodies such as jellyfish, snails, and, hearts are difficult to design using traditional skeleton‐based approaches. A standard approach is keyframing, but adjusting the shape of the flexible body for each key frame is tedious. In addition, the character cannot dynamically adjust its motion to respond to the environment or user input. This paper introduces a new procedural deformation framework (ProcDef) for designing and driving animations of such flexible objects. Our approach is to synthesize global motions procedurally by integrating local deformations. ProcDef provides an efficient design scheme for local deformation patterns; the user can control the orientation and magnitude of local deformations as well as the propagation of deformation signals by specifying line charts and volumetric fields. We also present a fast and robust deformation algorithm based on shape‐matching dynamics and show some example animations to illustrate the feasibility of our framework. 相似文献
22.
Vasileios Belagiannis Xinchao Wang Horesh Beny Ben Shitrit Kiyoshi Hashimoto Ralf Stauder Yoshimitsu Aoki Michael Kranzfelder Armin Schneider Pascal Fua Slobodan Ilic Hubertus Feussner Nassir Navab 《Machine Vision and Applications》2016,27(7):1035-1046
Multiple human pose estimation is an important yet challenging problem. In an operating room (OR) environment, the 3D body poses of surgeons and medical staff can provide important clues for surgical workflow analysis. For that purpose, we propose an algorithm for localizing and recovering body poses of multiple human in an OR environment under a multi-camera setup. Our model builds on 3D Pictorial Structures and 2D body part localization across all camera views, using convolutional neural networks (ConvNets). To evaluate our algorithm, we introduce a dataset captured in a real OR environment. Our dataset is unique, challenging and publicly available with annotated ground truths. Our proposed algorithm yields to promising pose estimation results on this dataset. 相似文献
23.
Yoshimitsu Aoki Shuji Hashimoto Masahiko Terajima Akihiko Nakasima 《The Visual computer》2001,17(2):121-131
We propose a prototype of a facial surgery simulation system for surgical planning and the prediction of facial deformation.
We use a physics-based human head model. Our head model has a 3D hierarchical structure that consists of soft tissue and the
skull, constructed from the exact 3D CT patient data. Anatomic points measured on X-ray images from both frontal and side
views are used to fire the model to the patient's head.
The purposes of this research is to analyze the relationship between changes of mandibular position and facial morphology
after orthognathic surgery, and to simulate the exact postoperative 3D facial shape. In the experiment, we used our model
to predict the facial shape after surgery for patients with mandibular prognathism. Comparing the simulation results and the
actual facial images after the surgery shows that the proposed method is practical. 相似文献
24.
Ongol MP Sawatari Y Ebina Y Sone T Tanaka M Tomita F Yokota A Asano K 《International journal of food microbiology》2007,116(3):358-366
Persistent acid production by Lactobacillus delbrueckii subsp. bulgaricus during refrigerated storage is a major cause of reduced viability of probiotic strains such as Bifidobacterium breve in yoghurt. It was established that H+ -ATPase-defective mutants of lactic acid bacteria have reduced growth and metabolism in low pH environments. Therefore, the aim of this study was to evaluate inhibition of post-acidification and maintenance of B. breve viability in yoghurt fermented by L. delbrueckii subsp. bulgaricus mutants with reduced membrane-bound H+ -ATPase activity during refrigerated storage. Spontaneous neomycin mutants of L. delbrueckii subsp. bulgaricus that had a significantly (P < or = 0.05) reduced H+ -ATPase activity were successfully isolated. Yoghurt fermented using L. delbrueckii subsp. bulgaricus SBT0164 No. 55-1 (mutant) starter culture had markedly reduced post-acidification and maintained viability (> or = 10(8) CFU/ml) of both Bifidobacteruim breve JCM 1192(T) and Bifidobacteruim breve JCM 7017 during storage at 10 degrees C for 21 days. These results clearly showed that yoghurt fermented by mutants of L. delbrueckii subsp. bulgaricus with reduced membrane-bound H+ -ATPase activity has reduced post-acidification that prolongs viability of B. breve in yoghurt during refrigerated storage. 相似文献
25.
Yoshimitsu Sagara Toru Komatsu Tasuku Ueno Kenjiro Hanaoka Takashi Kato Tetsuo Nagano 《Advanced functional materials》2013,23(42):5277-5284
Switching of the luminescence properties of molecular materials in response to mechanical stimulation is of fundamental interest and also has a range of potential applications. Herein, a water‐soluble mechanochromic luminescent pyrene derivative having two hydrophilic dendrons is reported. This pyrene derivative is the first example of a mechanochromic luminescent organic compound that responds to relative humidity. Mechanical stimulation (grinding) of this pyrene derivative in the solid state results in a change of the photoluminescence from yellow to green. Subsequent exposure to water vapor induces recovery of the initial yellow photoluminescence. The color change is reversible through at least ten cycles. It is also demonstrated that this compound can be applied as a mechano‐sensing material in frictional wear testing for grease, owing to its immiscibility in non‐polar solvents and its non‐crystalline behavior. Transmission electron microscope and atomic force microscope observations of samples prepared from dilute aqueous solutions of the pyrene derivative on suitable substrates, together with dynamic light scattering measurements for the compound in aqueous solution, indicate that this amphiphilic dumbbell‐shaped molecule forms micelles in water. 相似文献
26.
27.
Yoshimitsu Yamada Takashi Tsuchida Nyan Myint Kyaw Tatsuru Aoyama Moe Myint Su Hlaing Ryota Hashimoto 《Soils and Foundations》2019,59(6):2279-2298
Recently, a great deal of foreign investment has been entered into construction of the social infrastructure of Myanmar. Many construction projects are therefore on-going, and these are especially planned in the Yangon area. While these construction booms are increasing, existing studies on the geotechnical problems in the Yangon area such as problematic soils like soft clays are limited at present. Information on soil properties has also not been shared and has been confined to individual projects. In this paper, the boring and laboratory tests carried out in the Yangon area are selected and focused upon among the tests carried out in Myanmar. Laboratory test results for clay deposits in the Yangon area are analyzed and the differences in soil properties between different sedimentary basins and sub-areas divided by the Tertiary sediment ridge that runs from north to south at the center of Yangon are clarified together with a comparison to the clays found in other countries, which have been previously investigated. 相似文献
28.
Junya Hanaguri Harumasa Yokota Akifumi Kushiyama Sakura Kushiyama Masahisa Watanabe Satoru Yamagami Taiji Nagaoka 《International journal of molecular sciences》2022,23(3)
We investigated the effect of tofogliflozin, a sodium-dependent glucose cotransporter 2 inhibitor (SGLT2i), on retinal blood flow dysregulation, neural retinal dysfunction, and the impaired neurovascular coupling in type 2 diabetic mice. Tofogliflozin was added to mouse chow to deliver 5 mg/kg/day and 6-week-old mice were fed for 8 weeks. The longitudinal changes in the retinal neuronal function and blood flow responses to systemic hyperoxia and flicker stimulation were evaluated every 2 weeks in diabetic db/db mice that received tofogliflozin (n =6) or placebo (n = 6) from 8 to 14 weeks of age. We also evaluated glial activation and vascular endothelial growth factor (VEGF) expression by immunofluorescence. Tofogliflozin treatment caused a sustained decrease in blood glucose in db/db mice from 8 weeks of the treatment. In tofogliflozin-treated db/db mice, both responses improved from 8 to 14 weeks of age, compared with vehicle-treated diabetic mice. Subsequently, the electroretinography implicit time for the oscillatory potential was significantly improved in SGLT2i-treated db/db mice. The systemic tofogliflozin treatment prevented the activation of glial fibrillary acidic protein and VEGF protein expression, as detected by immunofluorescence. Our results suggest that glycemic control with tofogliflozin significantly improved the impaired retinal neurovascular coupling in type 2 diabetic mice with the inhibition of retinal glial activation. 相似文献
29.
Duchenne muscular dystrophy (DMD) is an X-linked recessive neuromuscular disorder with a prevalence of approximately 1 in 3500–5000 males. DMD manifests as childhood-onset muscle degeneration, followed by loss of ambulation, cardiomyopathy, and death in early adulthood due to a lack of functional dystrophin protein. Out-of-frame mutations in the dystrophin gene are the most common underlying cause of DMD. Gene editing via the clustered regularly interspaced short palindromic repeats (CRISPR) system is a promising therapeutic for DMD, as it can permanently correct DMD mutations and thus restore the reading frame, allowing for the production of functional dystrophin. The specific mechanism of gene editing can vary based on a variety of factors such as the number of cuts generated by CRISPR, the presence of an exogenous DNA template, or the current cell cycle stage. CRISPR-mediated gene editing for DMD has been tested both in vitro and in vivo, with many of these studies discussed herein. Additionally, novel modifications to the CRISPR system such as base or prime editors allow for more precise gene editing. Despite recent advances, limitations remain including delivery efficiency, off-target mutagenesis, and long-term maintenance of dystrophin. Further studies focusing on safety and accuracy of the CRISPR system are necessary prior to clinical translation. 相似文献
30.
N. Kawamoto T. Horikoshi K. Nomura H. Yokota Y. Negishi E. Tobita M. Terano 《应用聚合物科学杂志》2006,99(4):1350-1358
The aluminum aryloxide was prepared via the reaction of phenolic antioxidant, 3‐(3,5‐di‐t‐butyl‐4‐hydroxyphenyl)‐N‐octadecylpropionamide, with triethyl aluminum. Propylene polymerization using supported Ziegler–Natta catalyst systems was carried out in the presence of the antioxidant or its aluminum aryloxide. Although the antioxidant gave rise to decrease in catalyst yield and change in hydrogen response, the aluminum aryloxide had no influence on the catalytic polymerization behavior, and thus the obtained polymer characteristics such as molecular weight, polydispersity, and meso pentad as a stereoregularity were comparable to that polymerized without the antioxidant and the aluminum aryloxide. Polypropylene obtained in the presence of the aluminum aryloxide was well stabilized for oxidation and its stability was over 1000 h at 100°C (estimated to be over 30 years at room temperature). © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 99: 1350–1358, 2006 相似文献