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51.
Nakamura K. Takeda K. Toyoshima H. Noda K. Ohkubo H. Uchida T. Shimizu T. Itani T. Tokashiki K. Kishimoto K. 《Solid-State Circuits, IEEE Journal of》1997,32(11):1758-1765
A 32-b 500-MHz 4-1-1-1 operation 4-Mb pipeline burst cache SRAM has been developed. In order to achieve both high bandwidth operation and short latency operation, we developed the following technologies: 1) a prefetched pipeline-burst scheme with double late-write buffers, 2) gate size reduction and a bit-line equalization by source resetting, 3) point-to-point bidirectional coding I/O's to reduce bus noise and power consumption, and 4) a three-level metal 0.25-μm CMOS process technology with six transistor memory cells 相似文献
52.
Yamada M. Shimizu M. Horiguchi M. Okayasu M. 《Quantum Electronics, IEEE Journal of》1992,28(3):640-649
Temperature-dependent signal gain characteristics at signal wavelengths of 1.536 and 1.552 μm in Er3+-doped optical fibers with a temperature range of -40 to 80°C are reported for 0.98 and 1.48 μm pumping. The temperature dependences of signal gain strongly depend on fiber length, pump wavelength, and signal wavelength. The fiber length at which signal gain temperature insensitivity occurs is found for the amplification of a 0.98-μm-pump-1.536-μm-signal, a 0.98-μm-pump-1.552-μm-signal, and a 1.48-μm-pump-1.536-μm-signal. It is confirmed theoretically that the temperature dependences result from linear changes in the fluorescence, and absorption cross sections at the signal and pump wavelengths, and a shift in the effective pump wavelength 相似文献
53.
Yamada M. Shimizu M. Ohishi Y. Temmyo J. Kanamori T. Sudo S. 《Photonics Technology Letters, IEEE》1993,5(9):1011-1013
A highly efficient Pr3+-doped fluoride fiber amplifier configuration with an optical circulator, in which the input signal light is amplified both forward and backward through a Pr3+-doped fluoride fiber, is investigated with a view to decreasing the drive current and improving the reliability of pump laser diodes (LD's). With this double-path configuration, a 25-dB signal gain is achieved at an LD drive current of 110 mA. This LD drive current is about half that needed for a conventional single-path configuration. It is also found that this double-path configuration provides a double-gain coefficient, a slightly low saturation power, and a slightly narrow spectral gain width 相似文献
54.
Hamada M. Shimizu M. Okayasu M. Takeshita T. Horiguchi M. Tachikawa Y. Sugita E. 《Photonics Technology Letters, IEEE》1990,2(3):205-207
Measured noise characteristics of Er3+-doped optical fiber amplifiers pumped by 0.98- and 1.48-μm laser diodes (LDs) are reported. The noise figures estimated from the beat noise between signal and spontaneous emission are 3.2 dB for pumping by 0.98-μm LD and 4.1 dB for pumping by 1.48-μm LD. The beat noise between spontaneous emission components and the spontaneous shot noise for the 0.98-μm pumping are lower than those for the 1.48-μm pumping 相似文献
55.
Yamazaki S. Ono T. Shimizu H. Kitamura M. Emura K. 《Photonics Technology Letters, IEEE》1990,2(12):914-916
A 2.5-Gb/s CPFSK four-channel FDM transmission experiment has been conducted with a 150-km-long nondispersion-shifted fiber. This system employed a wideband channel space controller, a common polarization control, and a channel identification function. These were indispensable for realizing a high-capacity, coherent FDM trunk line system. The results of the experiment confirm the feasibility of trunk line systems with over 160-Gb/s capacity 相似文献
56.
A new technique to increase the effective sampling rate of an optical time-domain reflectometer using a time division multiplexing digital sampling averaging procedure is proposed. This permits an increase in distance measuring accuracy of an optical time-domain reflectometer. 相似文献
57.
Single or ten weekly subcutaneous injection(s) of 1, 2-dimethylhydrazine dihydrochloride were administered separately to Swiss mice. The repeated application gave rise mainly to high incidences of tumors in the large intestine. These neoplasms occurred most frequently in the colorectal area and in cecum adjacent to ileum. Light microscopically, these lesions were classified as polypoid adenomas and adenocarcinomas. Most of the adenocarcinomas were highly invasive, although they metastasized rarely. The fine structure of the malignant cells exhibited features typical of columnar absorptive cells. A distinctive alteration was the disorderly arrangement and abnormal size and shape of the microvilli. In addition, the cells exhibited numerous free ribosomes, little RER, priminent Golgi bodies, and uniformly dispersed nuclear chromatin. Morphologically, the intestinal tumors were similar to those found in man. In addition, the repeated administration of 1, 2-DMH also induced significant incidences of neoplasms in blood vessels, lungs, anus, and kidneys while the single application produced tumors in blood vessels and liver. The main hypotheses attempting to explain the selective induction of large intestinal neoplasms are discussed. 相似文献
58.
Sugano M Shimizu T Komatsu A Kakuta Y Hirano K 《Environmental science & technology》2011,45(6):2493-2497
Additive effects of glass powder upon the product yields and chlorine distribution after liquefaction of hydrothermally pretreated mixed waste (HMW) are compared with liquefaction of HMW with any one of water, quartz sand, or glass powder plus water. As a result, addition of either water or quartz sand did not affect liquefaction and dechlorination of HMW. Further, water (5 g) addition did not enhance liquefaction and dechlorination of HMW with glass powder. On the other hand, after liquefaction of HMW with glass powder, the yields of chlorine in the gas and water insoluble constituents decreased and the chlorine yield in the water-soluble constituent increased significantly. Because sodium in glass powder dissolved in a small amount (0.5 g) of water resulted from dehydration of HMW during liquefaction. Further, hydrogen chloride derived from polyvinylchloride in HMW was neutralized by ion exchange between H(+) and Na(+) dissolved in a small amount of water forming NaCl in the Residue (water-soluble) constituent. Therefore, most of chlorine in HMW was removed easily by water extraction of the Residue constituent after liquefaction of HMW with glass powder. Further, upgrading of HMW into the oil constituent was enhanced due to inhibition of production of chlorine containing organic compounds. Accordingly, it was clarified that glass powder was the most effective additive for liquefaction and dechlorination of HMW. 相似文献
59.
Mai Morozumi Hirohisa Izumi Takashi Shimizu Yasuhiro Takeda 《Journal of dairy science》2021,104(6):6463-6471
Extracellular vesicles (EV) are important for delivering biologically active substances to facilitate cell-to-cell communication. Milk-derived EV are widely known because of their potential for immune enhancement. However, procedures for isolating milk-derived EV have not been fully established. To obtain pure milk-derived EV and accurately reveal their function, such procedures must be established. The aim of the present study was to compare methods using commercially available kits for isolating milk-derived EV. Initially, we investigated procedures to remove casein, which is the major obstacle in determining milk-derived EV purity. We separated whey using centrifugation only, acetic acid precipitation, and EDTA precipitation. Then, we isolated milk-derived EV by ultracentrifugation, membrane affinity column, size exclusion chromatography (SEC), polymer-based isolation, or phosphatidylserine-affinity isolation. Using EV count per milligram of protein, which is a good indicator of purity, we determined that acetic acid precipitation was the best method for removing casein. Using nanoparticle tracking analysis, protein quantity analysis, and RNA quantity analysis, we comprehensively compared each isolation method for its purity and yield. We found that SEC-based qEV column (Izon Science) could collect purer milk-derived EV at higher quantities. Thus, a combination of acetic acid precipitation and qEV can effectively isolate high amounts of pure extracellular vesicles from bovine milk. 相似文献
60.
Anindita Mitra Yang-Fang Li Tobias G. Klämpfl Tetsuji Shimizu Jin Jeon Gregor E. Morfill Julia L. Zimmermann 《Food and Bioprocess Technology》2014,7(3):645-653
Sustaining the quality of seeds is a major task in attempting to supply nutrition to the growing world population. In this study, the seeds of Cicer arietinum were exposed to cold atmospheric plasma (CAP). A significant reduction of the natural microbiota attached to the seed surface was observed for increasing CAP treatment times—2 and 5 min were sufficient to achieve a 1 and 2 log reductions, respectively. Furthermore a 1 min CAP treatment showed a strongly improved seed germination (89.2 %), speed of germination (7.1?±?0.1 seeds/day), and increased seed vigor, beside a decrease in the mean germination time (2.7 days) compared with controls. The roughness profile of the seed cotyledon was altered significantly, only in case of longer treatment times from 5 min. These results suggest that CAP technology has the potentiality to reduce health risks associated with contaminated seeds, while improving food quality. 相似文献