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1.
Gil-Young Song Youngjoon Cheon Kihwang Lee Heuiseok Lim Kyung-Yong Chung Hae-Chang Rim 《Personal and Ubiquitous Computing》2014,18(6):1387-1403
As various forms of social media are spreading, we often witness that an idea of an individual user drives macroscopic changes. From the perspectives of product development and marketing, the opinions left by potential consumers in online social network can generate big ripple effects. This study analyzes the user opinions in online space to grasp preferences toward various products psychologically categorized by users. We also suggest an aspect of the market mentally configured by users using network modeling while following the framework of economic sociology. Existing analyses on online market place are mainly dealing with structural issues such as inter-actor relationships and status measurement. This study, however, analyzes complex preferences regarding diverse products and brands and derives a new model for inter-market connections. We expect that our study will provide important consequences on digital marketing and community design of corporations planning word of mouth effect in online space. 相似文献
2.
子午线轮胎出现不久,就采用钢丝带束层代替了纤维带束层,这对于实现子午线轮胎提高使用寿命和改善操纵性能的潜能是必要的。 相似文献
3.
Hyung Rim Reference to Choi Hyun Soo Reference to Kim Young Jae Reference to Park Kyoung Hwan Reference to Kim Myung Ho Reference to Joo Hyung Soo Reference to Sohn 《Decision Support Systems》2000,28(4):333
The sales activity of most parts manufacturing companies is based on orders of buyers. The process of promotion, receipt and selection of orders of the parts manufacturers is closely coupled with the load status of the production lines. On deciding whether to accept an order or not, as well as negotiating with buyers, sales persons need information such as load and schedule of production lines, and manufacturability of the order. Manufacturability analysis, process planning, and scheduling are therefore key features in developing an agent of sales activity for the parts manufacturing business. In this paper, an intelligent agent, a virtual manufacturing-based sales agent (VMSA) with multi-agent architecture is proposed to support the sales activity for the parts manufacturers in the Internet environment. A VMSA has an integrated architecture of agent and virtual manufacturing. The prototype of VMSA has been developed for a machine parts manufacturing company that has lathe machines, drilling machines, cutting machines, and milling machines. 相似文献
4.
For most small manufacturing companies, the selection and completion of orders placed by buyers are closely linked to the load status of their production lines. The decision to accept an order, or the selection of optimal order set, critically depends on the production schedule when orders exceed production capacity. However, production scheduling is mainly performed by human experts, and small companies lack resources to implement such a task. As a result, most small manufacturers suffer from the difficulty to meet due dates or to make proper decision in accepting new orders. To address this problem, this paper develops an automatic agent that selects an optimal set of orders using commonly available Internet technology. The main engine of the selection agent is based on a typical job shop scheduling model, formulating and implementing it as an Integer Program (IP) model. We also translate IP into Genetic Algorithm (GA) to address its NP-hard problem. We conclude with a suggestion for an agent architecture that tackles Web-based order selection problems. 相似文献
5.
Ji Hyun Lee Ji Woong Kim Ha Rim Yang Seong-Won Song Song-Jae Lee Yeongha Jeon Anna Ju Narim Lee Min-Gu Kim Minjoo Kim Kyusang Hwang Jin Hwan Yoon Hyunbo Shim Sukmook Lee 《International journal of molecular sciences》2022,23(13)
Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer and the leading cause of global cancer-related mortality. Despite the earlier identification of membrane-proximal cleavage of cell adhesion molecule 1 (CADM1) in cancers, the role of the membrane-bound fragment of CAMD1 (MF-CADM1) is yet to be clearly identified. In this study, we first isolated MF-CADM1-specific fully human single-chain variable fragments (scFvs) from the human synthetic scFv antibody library using the phage display technology. Following the selected scFv conversion to human immunoglobulin G1 (IgG1) scFv-Fc antibodies (K103.1–4), multiple characterization studies, including antibody cross-species reactivity, purity, production yield, and binding affinity, were verified. Finally, via intensive in vitro efficacy and toxicity evaluation studies, we identified K103.3 as a lead antibody that potently promotes the death of human SCLC cell lines, including NCI-H69, NCI-H146, and NCI-H187, by activated Jurkat T cells without severe endothelial toxicity. Taken together, these findings suggest that antibody-based targeting of MF-CADM1 may be an effective strategy to potentiate T cell-mediated SCLC death, and MF-CADM1 may be a novel potential therapeutic target in SCLC for antibody therapy. 相似文献
6.
Ki-Young Shin Yong Hoon Rim Youn Soo Kim Hyo Shin Kim Jae Woong Han Chang Hyun Choi Kyung Suk Lee Joung Hwan Mun 《Journal of Mechanical Science and Technology》2010,24(9):1901-1909
Gait analysis using 3D motion capture systems provides joint kinematic and kinetic analysis results such as joint relative
angles and moments that can be use used to evaluate the degrees of pathological gait patterns. However, the complex data produced
using these 3D motion capture systems can only analyzed by experts, because the gait analysis is highly coupled to the kinematics
of each joint. Therefore, several Several previous studies using gait analysis have relied on the data compression technique
to represent gait deviation from the average normal profiles as a single value. Even though it is important to evaluate gait
pathologies at the joint level, all these previous studies have just used a single value to evaluate the pathological gait
pattern. Using just one variable for evaluation of a gait is limited in terms of determining which joint movement patterns
are getting better during rehabilitation. Therefore, in this study, a method suitable for evaluating gait deviation during
a gait was developed to provide three indices for the hip, knee and ankle joints. In addition, to validate the proposed method
in clinical cases, experimental tests were conducted on thirty thirty-six normal walkers and six patients with cerebral palsy.
Furthermore, to validate the proposed method in regards to rehabilitation, experimental tests were conducted on three classified
walking groups with imposed ankle equinus constraints. The JNI for the hip joint, knee joint and ankle were 8.78 (±3.70),
2.92 (±3.25) and 8.79 (±4.38), respectively, in the normal walking group. However, these values were significantly different
for the pathological walking group with cerebral palsy. The JNI of the hip joint, knee joint and ankle joint were 203.73 (±171.59),
81.23 (±52.13) and 248.39 (±149.99), respectively, for this group. There were also differences between any two of the three
classified groups with imposed ankle equinus constraints. In particular, the JNI of the ankle joint was statistically different
at the p<0.01 level, and this parameter clearly increased as the degree of the imposed ankle equinus was increased. These
results demonstrate that the proposed JNI can be used as a scalar factor to evaluate the angular deviation of each joint in
normal and patient groups. In addition, this approach can be adapted to evaluate rehabilitation and pre/post surgery. 相似文献
7.
Insun Song Jongseop Rim Jaemin Lee Inseok Jang Bosung Jung Kisoo Kim Soonchul Lee 《International journal of molecular sciences》2022,23(3)
Mesenchymal stem cells (MSCs) have emerged as a promising therapeutic approach for diverse diseases and injuries. The biological and clinical advantages of human fetal MSCs (hfMSCs) have recently been reported. In terms of promising therapeutic approaches for diverse diseases and injuries, hfMSCs have gained prominence as healing tools for clinical therapies. Therefore, this review assesses not the only biological advantages of hfMSCs for healing human diseases and regeneration, but also the research evidence for the engraftment and immunomodulation of hfMSCs based on their sources and biological components. Of particular clinical relevance, the present review also suggests the potential therapeutic feasibilities of hfMSCs for musculoskeletal disorders, including osteoporosis, osteoarthritis, and osteogenesis imperfecta. 相似文献
8.
Rim Ben Abdallah Ana Belén Bautista-Ortin Tesnime Ghazouani Wafa Talbi Maria D. Jiménez-Martinez Encarna Gómez-Plaza Sami Fattouch 《International Journal of Food Science & Technology》2019,54(5):1633-1641
During technological processing, proanthocyanidins and anthocyanidins could be partly lost due to the complexation phenomena, affecting food and beverage nutritional properties, organoleptic properties and health-promoting potentials. A common issue is encountered when processing food and beverage which is binding of phenolics to dietary proteins. The present investigation aims at evaluating the proteolysis contribution, using pure protease (Pepsin, 3000 units g−1), to protein–anthocyanidin and protein–proanthocyanidin interactions. Bovine serum albumin (BSA), ovalbumin (OVA) and casein (CAS) dietary protein models were used. High-performance liquid chromatography coupled to diode array detector (HPLC-DAD) and size exclusion chromatography analyses proved that pepsin treatment significantly (P > 0.05) decreased the ratio of flavonoids’ interaction with tested proteins . The proteolysis reduced anthocyanidin interactions with CAS, OVA and BSA by 64.88%, 57.37% and 42.87% respectively. Similarly, proanthocyanidins interaction with CAS, OVA and BSA were reduced by 34.23%, 13.74% and 2.39% respectively. This study provides the basis to develop innovative technologies to limit protein–flavonoid complexation during food and beverage processing. 相似文献
9.